Results 191 to 200 of about 574,104 (383)
In this study, a novel mechanism is unveiled by which ADD1, acting as a molecular switch, coordinates actin branch dynamics and the transport of endocytic viruses and cargoes. Phosphorylation of ADD1 at Ser726 reduces actin branch density, enhancing endosome fusion and attachment to microtubules.
Meijun Jiang+10 more
wiley +1 more source
Ubiquitin is the ATP-dependent proteolysis factor I of rabbit reticulocytes.
Keith D. Wilkinson+2 more
openalex +1 more source
Identification of a viral gene encoding a ubiquitin-like protein. [PDF]
Linda A. Guarino
openalex +1 more source
GbSER02 with a single base change (SNP517G) encodes normal serpin protein and interacts with transcription factor VOZ1 to alleviate the repression of VOZ1 on GA3ox1 and promote GA3 biosynthesis. Further, GA3 induces the expression of cell wall loosening‐related genes and decreases flavonoid content, ultimately facilitating fiber cell elongation in ...
Hao Jia+12 more
wiley +1 more source
Spatiotemporal Regulation of STING Activity by Linear Ubiquitination Governs Antiviral Immunity
This study uncovers a spatiotemporal regulation of STING activity by linear ubiquitination in antiviral immunity. At the early stage of the infection, LUBAC promotes STING linear ubiquitination to drive its trafficking from the ER to the Golgi apparatus for activation.
Yong Zhang+13 more
wiley +1 more source
Immunogold localisation of ubiquitin‐protein conjugates in primary (azurophilic) granules of polymorphonuclear neutrophils [PDF]
Lajos László+6 more
openalex +1 more source
This study identifies MTCH2 as a crucial regulator of ferroptosis in colorectal cancer (CRC) progression. High expression of MTCH2 is correlated with poor prognosis in CRC patients. Furthermore, MTCH2 depletion induces ferroptosis to suppress CRC liver metastasis via the E2F4/TFRC axis and sensitizes tumors to sorafenib treatment, supporting MTCH2 as a
Pu Xing+18 more
wiley +1 more source
Myosin, as a type of molecular motor, is mainly involved in muscle contraction. Recently, myosin research has made considerable progress. However, the function of Bombyx mori myosin remains unclear.
L J Hao+6 more
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