Results 231 to 240 of about 574,104 (383)

Regulation of placental development and function by ubiquitination. [PDF]

Mol Med
Wang X, Li X, Yuan S, Gu Z, An Z, Xu Q, Cao B, Song Y, Tang C.   +8 more
europepmc   +1 more source

Novel Cyano‐Artemisinin Dimer ZQJ29 Targets PARP1 to Induce Ferroptosis in Pancreatic Cancer Treatment

Advanced Science, EarlyView.
A novel artemisinin derivative dimer has been synthesized, and its significant potential as an anti‐cancer agent. The study indicated that ZQJ29 effectively inhibited the proliferation of pancreatic cancer cells in vitro and in vivo. Additionally, these investigations have unveiled ZQJ29 as a new potent PARP1 inhibitor, with the capability to induce ...
Jianping Chen, Lingyun Yue, Yanna Pan, Bingying Jiang, Junfeng Wan, Haixia Lin, Fujiang Guo, Huiyu Li, Yajuan Li, Qingjie Zhao   +9 more
wiley   +1 more source

A ubiquitin conjugating enzyme encoded by African swine fever virus. [PDF]

, 1992
Pascal Hingamp, J.E. Arnold, R. John Mayer, Linda K. Dixon   +3 more
openalex   +1 more source

Examining the Role of Threonine Phosphorylation in Ubiquitin's Function Using Chemical Protein Synthesis. [PDF]

JACS Au
Wang B, Li C, Zhao F, Shi L, Li X, Liu Y, Sun S, Yuan L, Sun M, Zhang Y, Shi J, Liang LJ.   +11 more
europepmc   +1 more source

A Novel OsMPK6‐OsMADS47‐PPKL1/3 Module Controls Grain Shape and Yield in Rice

Advanced Science, EarlyView.
OsMADS47 is identified as a key regulator governing rice grain morphology. Phosphorylation‐dependent regulation of its activity directs the development of slender versus round grains, modulating both yield and appearance. This mechanism bridges cellular signaling with transcriptional regulation, establishing a molecular framework for grain optimization.
Jingjing Fang, Yan Chun, Fan Zhang, Tingting Guo, Mengmeng Ren, Jinfeng Zhao, Shoujiang Yuan, Wensheng Wang, Yunhai Li, Xueyong Li   +9 more
wiley   +1 more source

Diabetes, hipoxia e doenças cardiovasculares: do mecanismo molecular ao tratamento

Revista Portuguesa de Cardiologia, 2017
João Vasco Ferreira
doaj  

Over-expression of ubiquitin carboxy terminal hydrolase-L1 induces apoptosis in breast cancer cells

, 1992
Liu
openalex   +2 more sources

Ubiquitin Azapeptide Esters as Next-Generation Activity-Based Probes for Cysteine Enzymes in the Ubiquitin Signal Pathway. [PDF]

J Am Chem Soc
Chanda S, Atla S, Sheng X, Nyalata S, Alugubelli YR, Coleman DD, Jiang W, Lopes R, Guo S, Wand AJ, Zhao Y, Liu WR.   +11 more
europepmc   +1 more source

Nephronectin (NPNT) is a Crucial Determinant of Idiopathic Pulmonary Fibrosis: Modulating Cellular Senescence via the ITGA3/YAP1 Signaling Axis

Advanced Science, EarlyView.
Through a comprehensive multi‐omics analysis, this study identifies a marked reduction in Nephronectin (NPNT) expression within fibrotic lung tissue. This reduction impairs the binding capability to the ITGA3 receptor, consequently causing YAP1 to persist in the cytoplasm, where it undergoes degradation.
Jiayu Guo, Yan Wang, Qiudi Liu, Zhaoyang Luo, Xiaomu Tian, Yuquan Wang, Yang Liu, Zhiwei Ning, Yingying Guo, Huiying Gao, Xinyue Wang, Jinglong Feng, Mengmeng Liu, Dina Saifullina, Yixin Zhang, Tengfei Pan, Yu Bian, Tao Ban, Tianyu Li, Yunyan Gu, Haihai Liang   +20 more
wiley   +1 more source

Complete reconstitution of conjugation and subsequent degradation of the tumor suppressor protein p53 by purified components of the ubiquitin proteolytic system [PDF]

, 1994
Dganit Shkedy, Hedva Gonen, Beatrice Bercovich, Aaron Ciechanover   +3 more
openalex   +1 more source