Results 191 to 200 of about 232,343 (304)

The E3 ubiquitin ligase FBXL18 stabilizes BST2 to promote inflammation in RABV-infected astrocytes. [PDF]

Nat Commun
Wang J, Guo J, Li N, Tu Z, Liu S, Ma J, Zhang X, Cheng H, Hao Z, Feng Y, Lv S, Tai G, Zhou Y, Fu J, Tu C, Liu Y.   +15 more
europepmc   +1 more source

Alternative Translation Initiation in PRKN Delays the Onset of Parkinson's Disease and Offers a Therapeutic Target

Annals of Neurology, EarlyView.
Objective Biallelic variants in PRKN cause autosomal recessive Parkinson's disease (PD) with a median age at onset of 31 years. When evaluating the 16 previously published carriers of a homozygous deletion of Exon 2 from the International Parkinson's Disease and Movement Disorder Society Gene Database (MDSGene) database, the median age at onset is ...
Arian Hach, Katja Lohmann, Manabu Funayama, Poornima J. Menon, Eva‐Juliane Vollstedt, Teresa Kleinz, Hiroyo Yoshino, Suzanne Lesage, Britta Meier, Carolyn M. Sue, Jean‐Christophe Corvol, Alexis Brice, Nobutaka Hattori, Christine Klein, Aleksandar Rakovic   +14 more
wiley   +1 more source

Unraveling the role of Cullin3 of E3 ubiquitin ligase in salt stress tolerance via proteomics. [PDF]

BMC Plant Biol
Herwibawa B, Lekklar C, Roytrakul S, Ito T, Chadchawan S, Buaboocha T.   +5 more
europepmc   +1 more source

The Putative E3 Ubiquitin Ligase TEX1 Is Required for Nuclear Biology and Developmental Progression of Plasmodium berghei in the Liver. [PDF]

Cells
Schmid M, Golomingi R, Franke-Fayard B, Caldelari R, Rehmann R, Roques M, Heussler VT.   +6 more
europepmc   +1 more source

Regulation of PD-L1 Protein Expression by the E3 Ubiquitin Ligase GP78. [PDF]

Curr Issues Mol Biol
Chatterjee M, Pimentel JM, Zhou JY, Mugunamalwaththa T, Yang Z, Raz A, Wu GS.   +6 more
europepmc   +1 more source

The E3 Ubiquitin Ligase UBE3B Regulates Synaptic Development and Cortical Network Activity

Autism Research, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impaired communication, abnormal social interactions, and restricted, repetitive behaviors. Pathogenic mutations in UBE3B result in neurodevelopmental disease, including intellectual disability, lack of speech, and ASD.
Shayal Vashisth, Aleya Shedd, Ariel Aiken, Solmi Cheon, Josh Bandopadhay, Kiran Kaur, Kimberly M. Huber, Maria H. Chahrour   +7 more
wiley   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source

Regulation of host immunity by a novel Legionella pneumophila E3 ubiquitin ligase. [PDF]

PLoS Pathog
Liu S, He C, Zhang Y, Liu S, Chen TT, Li C, Chen D, Ouyang S, Song L, Fu J, Luo ZQ.   +10 more
europepmc   +1 more source

Synthetic Strategies for Activity‐Based Probes to Decode Ubiquitin‐Like Modifiers

Chemistry – A European Journal, EarlyView.
ABSTRACT Ubiquitin‐like proteins (Ubls) such as SUMO, NEDD8, ISG15, URM1, UFM1, FAT10, ATG8/ATG12, and FUBI are essential regulators of cellular homeostasis, controlling processes from protein stability and trafficking to immune signaling and autophagy.
Saibal Chanda, Alan Pham, SreeNidhi Karnati, Natalia Soto Rodriguez, Alyssa Toner, Wenshe Ray Liu   +5 more
wiley   +1 more source

The membrane-associated ubiquitin ligase MARCHF8 degrades MHC-I in HPV-positive head and neck cancer for immune evasion. [PDF]

Proc Natl Acad Sci U S A
Khalil MI, Wang J, Vu L, Yang C, Yin C, Chadha S, Nabors H, Vocelle D, May DG, Chrisopulos RJ, Welbon CC, Zhou L, Roux KJ, Spanos WC, Bernard MP, Mi QS, Pyeon D.   +16 more
europepmc   +1 more source