Results 271 to 280 of about 308,731 (375)

RAB40C recruiting TRIM21 facilitates the progression of hepatocellular carcinoma by stabilizing EGFR. [PDF]

Cell Commun Signal
Wang Y, Yu R, Yan J, Shao L, Zhao J, Xu Q, Wen D, Di X, Dong Z, Dai R, Li H, Zhang S, Jiang H.   +12 more
europepmc   +1 more source

Macrophage TRIM21 Inhibition Ameliorates Murine Acute Pancreatitis via PHB2‐Mediated Mitochondrial Stabilization

Advanced Science, EarlyView.
Macrophage‐derived TRIM21 drives the progression of AP via ubiquitin‐proteasome‐mediated degradation of PHB2, leading to impaired PHB2‐mediated mitophagy. Therefore, accumulation of cytosolic mtDNA hyperactivates the cGAS‐STING signaling axis, thereby amplifying inflammatory cascades.
Yansong Xu, Yuansong Sun, Xin Zhou, Kai Song, Chunlin Yin, Zhaohua Wang, Fei Xie, He Li   +7 more
wiley   +1 more source

Natural genetic variation of a single amino acid in beet necrotic yellow vein virus P31 protein modulates evasion of plant ubiquitination-mediated antiviral immunity. [PDF]

PLoS Pathog
Guo ZH, Qin XY, Zhou MK, Zhang XQ, Li ZY, Zheng C, Zhang ZY, Chen Q, Wang XB, Han CG, Wang Y.   +10 more
europepmc   +1 more source

Table S4 from FBXO24 suppresses breast cancer tumorigenesis by targeting LSD1 for Ubiquitination

Bo Dong, Xiang Song, Xinzhao Wang, Tao Dai, Jianlin Wang, Zhiyong Yu, Jiong Deng, B. Mark Evers, Yadi Wu   +8 more
openalex   +1 more source

Ubiquitination and DNA Repair in Multiple Myeloma

, 2018
Lisa Crawford, Alexandra E. Irvine
openalex   +2 more sources

ubiquitin

Citation: 'ubiquitin' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13767 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Hepatocyte BPGM Induces RET Lactylation and Macrophage Reprogramming to Promote Tumorigenesis in Hepatocellular Carcinoma

Advanced Science, EarlyView.
Mechanistic schematic diagram.BPGM promotes the expression level of RET by increasing the lactylation of RET‐K549 and inhibiting its ubiquitination levels in HCC cells. Furthermore, BPGM in HCC cells could also promote M2 polarization in macrophages through lactate secretion. Both of the mechanisms could promote the progression of HCC. ABSTRACT Aerobic
Jiajia Zhang, Lu Shi, Liangliang Lin, Yang Zhang, Miao Zhang, Lili Wu, Yong Xia, Yaqiong Zhang, Peng Han, Likun Zhuang, Liang Shi   +10 more
wiley   +1 more source

SENP6 Restrains NLRP3 Inflammasome Activation via DeSUMOylation-Driven K48-Linked Ubiquitination of NLRP3 in Acute Lung Injury. [PDF]

Research (Wash D C)
Gu A, Wang B, Zhang Y, Sun C, Wei Y, Yan J, Yang Y, Wang Y, Liu R, Zhang R, Liu J, Gu C, Wang Y.   +12 more
europepmc   +1 more source

NS1 binding protein regulates stress granule dynamics and clearance by inhibiting p62 ubiquitination [PDF]

Jin‐A Lee, Pureum Jeon, Hyun-Ji Ham, Haneul Choi, Semin Park, Jae-Woo Jang, Sang-Won Park, Ssang‐Goo Cho, Hyun-Jung Lee, Hyun Kyu Song, Masaaki Komatsu, Deok‐Jin Jang   +11 more
openalex   +1 more source

SIRT5–RAC2 Axis Drives Monocyte‐to‐Macrophage Differentiation to Promote Inflammatory Injury in Premature Ovarian Insufficiency

Advanced Science, EarlyView.
SIRT5 desuccinylates and stabilizes RAC2, activating CSF1R‐dependent signaling to drive monocyte differentiation into M0 macrophages and their polarization toward pro‐inflammatory M1 phenotypes in CTX‐induced premature ovarian insufficiency. Inhibiting the SIRT5‐RAC2 axis attenuates inflammation, reduces granulosa cell apoptosis, and preserves ...
Wenjing TanTai, Yaqi Li, Shengnan Liu, Minjuan Wu, Zhixiao Liu, Junfeng Jiang, Jingjing Chen, Xiaoding Xu, Li Li, Chaoqun Li, Fang Zhao, Ye Liu, Haitao Ni, Tengfei Zhang, Mingjuan Xu, Chaofeng Han   +15 more
wiley   +1 more source