Results 131 to 140 of about 851 (145)

Proteome Birthdating: A Single-Sample Approach for Measuring Global Turnover Dynamics and "Protein Age". [PDF]

Bio Protoc
Meadow ME, Broas S, Hoare M, Ahmed M, Alimohammadi F, Welle KA, Swovick K, Hryhorenko JR, Jain A, Martinez JC, Seluanov A, Gorbunova V, Buchwalter A, Ghaemmaghami S.   +13 more
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Autophagy in proteostasis and aging in Caenorhabditis elegans. [PDF]

Cell Stress Chaperones
Lange CM, Higuchi-Sanabria R, Kumsta C.
europepmc   +1 more source

Paraptosis Turning Cellular Stress into Therapeutic Weapon for Urological Diseases. [PDF]

Research (Wash D C)
Wang J, Zhang Q, Zhou C, Lyu Z, Feng D.
europepmc   +1 more source

Strigolactone signaling through the eye of the mass spectrometer [PDF]

, 2016
Walton, Alan
core  

Cross-family small GTPase ubiquitination by the intracellular pathogen Legionella pneumophila. [PDF]

Mol Biol Cell
Steinbach A, Bhadkamkar V, Jimenez-Morales D, Stevenson E, Jang GM, Krogan NJ, Swaney DL, Mukherjee S.   +7 more
europepmc   +1 more source

Ubiquitination mediates protein localization in RNA virus-infected cells

Shi S, Iesmantavicius V, Sabu AS, Soneson C, Kohler H, Sanchez J, Ghosh S, Cao C, Huang Y, Matthias G, Yamauchi Y, Matthias P, Wang L.   +12 more
europepmc   +1 more source

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Proteomic approaches to study ubiquitinomics

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2023
As originally described some 40 years ago, protein ubiquitination was thought to serve primarily as a static mark for protein degradation. In the ensuing years, it has become clear that 'ubiquitination' is a structurally diverse and dynamic post-translational modification and is intricately involved in a myriad of signaling pathways in all eukaryote ...
Indrajit, Sahu, He, Zhu, Sara J, Buhrlage, Jarrod A, Marto   +3 more
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Evaluation of DDA Library-Free Strategies for Phosphoproteomics and Ubiquitinomics Data-Independent Acquisition Data

Journal of Proteome Research, 2023
Phosphoproteomics and ubiquitinomics data-independent acquisition (DIA) mass spectrometry (MS) data is typically analyzed by using a data-dependent acquisition (DDA) spectral library. The performance of various library-free strategies for analyzing phosphoproteomics and ubiquitinomics DIA MS data has not been evaluated. In this study, we systematically
Chengwen Wen, Xiurong Wu, Guanzhong Lin, Wei Yan, Guohong Gan, Xiao Xu, Xiang-Yu Chen, Xi Chen, Xianming Liu, Guo Fu, Chuan-Qi Zhong   +10 more
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Hsp90 inhibition induces both protein-specific and global changes in the ubiquitinome

Journal of Proteomics, 2015
Inhibition of the essential chaperone Hsp90 with drugs causes a global perturbation of protein folding and the depletion of direct substrates of Hsp90, also called clients. Ubiquitination and proteasomal degradation play a key role in cellular stress responses, but the impact of Hsp90 inhibition on the ubiquitinome has not been characterized on a ...
Manfredo, Quadroni, Alexandra, Potts, Patrice, Waridel   +2 more
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Large-Scale Filter-Aided Sample Preparation Method for the Analysis of the Ubiquitinome

Analytical Chemistry, 2017
Protein ubiquitination regulates key cellular functions, including protein homeostasis and signal transduction. The digestion of ubiquitinated proteins with trypsin yields a glycine-glycine remnant bound to the modified lysine residue (K-ε-GG) that can be recognized by specific antibodies for immunoaffinity purification (IAP) and subsequent ...
Albert Casanovas, Roberto Pinto-Llorente, Montserrat Carrascal, Joaquin Abian   +3 more
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