Results 211 to 220 of about 117,989 (312)

Cloning, bioinformatics analysis, and expression of the ubiquitin 2 (ubq-2) gene from the dog roundworm <i>Toxocara canis</i>. [PDF]

Front Vet Sci
Zhu P, Hu X, Huang J, Wang L, Wang Z, Wang R, Fan X, Wei G, He Q, Li Z, Zhou X, Wang H, Xie Y.   +12 more
europepmc   +1 more source

Halorotetin B, A Novel Terpenoid Compound Derived from Marine Ascidian, Suppresses Tumor Growth by Targeting the Cell Cycle Regulator UBE2C

Advanced Science, EarlyView.
Halorotetin B, a novel small‐molecule terpenoid identified from an edible marine ascidian, exhibits strong anti‐tumor activity both in vitro and in vivo through direct targeting UBE2C to induce tumor cell cycle arrest and then lead tumor cell senescence. As a newly discovered UBE2C inhibitor, Halorotetin B can serve as a novel potential cell senescence
Shanhao Han, Jianhui Li, Yuting Zhu, Penghui Liu, Yaoyao Zheng, Muchun He, Bo Dong   +6 more
wiley   +1 more source

CUL1-neddylation contributes to K29-linked ubiquitination on p27 for autophagic degradation in sorafenib-resistant liver cancer. [PDF]

Cell Biol Toxicol
Xu H, Zheng S, Zhang Q, Xu Y, Zhang H, Hu T, Zhang X, E J, Li X, Wang R, Liu H, Xie R.   +11 more
europepmc   +1 more source

Participation of proteasome-ubiquitin protein degradation in autophagy and the activation of AMP-activated protein kinase

, 2015
Shaoning Jiang, Dae Won Park, Yong Gao, Saranya Ravi, Victor Darley‐Usmar, Edward Abraham, Jaroslaw W. Zmijewski   +6 more
openalex   +1 more source

Acetylation Regulates ACSL4 Degradation Through Chaperone‐Mediated Autophagy to Alleviate Intervertebral Disc Degeneration

Advanced Science, EarlyView.
Intervertebral disc degeneration is triggered by ACSL4 accumulation‐mediated ferroptosis of nucleus pulposus cells due to CMA dysfunction. KAT2B promotes ACSL4 degradation via CMA through acetylation. AAV‐mediated LAMP2A delivery or engineered exosomes rescue nucleus pulposus cell senescence and disc degeneration.
Zhouwei Wu, Zhichen Jiang, Chenglong Hong, Shu Yang, Shuqing Jin, Chenyu Wu, Kaijie Guo, Jiang Liu, Shaobo Xu, Chenggui Wang, Xiangyang Wang   +10 more
wiley   +1 more source

DOO: integrated multi-omics resources for deep ocean organisms. [PDF]

Nucleic Acids Res
She J, Qian PY, Wu L.
europepmc   +1 more source

The ubiquitin-specific protease family from Arabidopsis. AtUBP1 and 2 are required for the resistance to the amino acid analog canavanine.

Plant Physiology, 2000
Ning Yan, J. H. Doelling, T. Falbel, Adam M. Durski, R. Vierstra   +4 more
semanticscholar   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

Unraveling chain specific ubiquitination in cells using tandem ubiquitin binding entities. [PDF]

Sci Rep
Ali MS, Rainville C, Pedroza J, Sterner DE, Wang H, Suresh K, Butt TR.   +6 more
europepmc   +1 more source

NMR chemical shift assignment of UEV domain of Ubiquitin-conjugating enzyme E2 variant 3 lactate dehydrogenase (UEVLD)

Nyenhuis, David A., Vazquez, Jose G., Strub, Marie-Paule, Tjandra, Nico   +3 more
openalex   +1 more source