Results 211 to 220 of about 117,949 (359)

Immunogold localisation of ubiquitin‐protein conjugates in primary (azurophilic) granules of polymorphonuclear neutrophils [PDF]

, 1991
Lajos László, F J Doherty, Adrian J. Watson, Tim Self, Michael Landon, James Lowe, R. John Mayer   +6 more
openalex   +1 more source

Ubiquitin Lys63 is involved in ubiquitination of a yeast plasma membrane protein

EMBO Journal, 1997
J. Galan, R. Haguenauer‐Tsapis
semanticscholar   +1 more source

TRIP12 structures reveal HECT E3 formation of K29 linkages and branched ubiquitin chains. [PDF]

Nat Struct Mol Biol
Maiwald SA, Schneider LA, Vollrath R, Liwocha J, Maletic MD, Swatek KN, Mulder MPC, Schulman BA.   +7 more
europepmc   +1 more source

SIRT6 Lysine‐Demyristoylates ATF2 to Ameliorate Vascular Injury via PRKCD/VE‐Cadherin Pathway Regulating Vascular Endothelial Barrier

Advanced Science, EarlyView.
A novel modified SIRT6 variant (dSIRT6) H133Y‐mediated enrichment technique unmasks 15 new human lysine‐myristoylated proteins. Notably, Sirtuin 6 (SIRT6) demyristoylation of activating transcription factor 2 (ATF2) at K296 orchestrates its nucleoplasmic translocation.
Runyang Feng, Zheyan Fang, Shuang Zhao, You‐en Zhang, Na Wu, Zhenyang Guo, Xin Zhong, Bixuan Jiang, Hongfei Xu, Hangnan Hong, Zhentao Zhang, Mukaddas Abdurahman, Xueting Yu, Jilong Geng, Xiansu Nie, Supuya Abuduwahapi, Dong Huang, Gang Zhao, Wenbin Zhang, Hao Lu, Li Shen, Xin Zhao, Zhaoyang Chen, Junjie Guo, Hongchao Zheng, Yue He, Sanwu Wu, Jiayin Peng, Jiawen Song, Xiao Wang, Haomin Li, Yuli Huang, Shengying Qin, Haojie Lu, Xiangdong Wang, Jianguo Zhao, Lei Huang, Yun Zhao, Peng Li, Junbo Ge, Hua Li   +40 more
wiley   +1 more source

Characterization of a ubiquitin-fusion gene from the tobacco hawkmoth,Manduca sexta [PDF]

, 1990
Stephen T. Bishoff, Lawrence M. Schwartz
openalex   +1 more source

Ubiquitin recruiting chimera: more than just a PROTAC. [PDF]

Biol Direct
Grigoreva TA, Novikova DS, Melino G, Barlev NA, Tribulovich VG.   +4 more
europepmc   +1 more source

Preservation of ALYREF Phase Separation Mitigates Doxorubicin‐Induced Cardiomyocyte DNA Damage and Cardiotoxicity

Advanced Science, EarlyView.
Binding of Doxorubicin to ALYREF disrupts its phase‐separated condensate and induces DNA damage and apoptosis in cardiomyocytes Abstract The clinical utility of the anticancer agent doxorubicin (DOX) is limited by its dose‐dependent cardiotoxicity.
Xinlu Gao, Yifu Shen, Zhihui Xiao, Zhenbo Han, Xu Liu, Ao Cai, Yanan Tian, Guang Lian, Wenya Ma, Yining Liu, Rui Gong, Hanjing Li, Xiuxiu Wang, Zhongyu Ren, Naufal Zagidullin, Lei Yu, Ye Tian, Yu Liu, Zhenwei Pan, Baofeng Yang, Benzhi Cai   +20 more
wiley   +1 more source

Regulatory subunits of cAMP-dependent protein kinases are degraded after conjugation to ubiquitin: a molecular mechanism underlying long-term synaptic plasticity.

, 1993
Ashok N. Hegde, Alfred L. Goldberg, James H. Schwartz   +2 more
openalex   +1 more source

Interleukin 6 receptor antibody inhibits muscle atrophy and modulates proteolytic systems in interleukin 6 transgenic mice.

Journal of Clinical Investigation, 1996
T. Tsujinaka, J. Fujita, C. Ebisui, Masahiko Yano, E. Kominami, Koichi Suzuki, Keiji Tanaka, A. Katsume, Y. Ohsugi, H. Shiozaki, M. Monden   +10 more
semanticscholar   +1 more source

Targeting Methylglyoxal Metabolism to Enhance Ferroptosis Sensitivity in Tumor Therapy

Advanced Science, EarlyView.
This study reveals how blocking a detox enzyme called GLO1 increases the buildup of a toxic molecule, methylglyoxal (MGO), which triggers cancer cell death by ferroptosis. A protein called PJA1 drives this process. Targeting the PJA1–GLO1 pathway boosts the effectiveness of ferroptosis‐inducing treatments in tumors, offering a promising approach for ...
Xinyue Zhang, Leng Han, Zimu Wang, Hanghui Yu, Jiao Liu, Rui Kang, Daolin Tang, Zhengjia Liu, Xianlong Du, Enyong Dai   +9 more
wiley   +1 more source