Results 111 to 120 of about 68,086 (202)

UDP-glycosyltransferase confers anthranilic diamide resistance in Bemisia tabaci

Journal of Advanced Research
UDP-glycosyltransferases (UGTs) are key Phase II detoxification enzymes in insects, playing a crucial role in resistance to a variety of insecticides, including diamides. Cyantraniliprole (CYA) is a systemic diamide insecticide with high toxicity against Bemisia tabaci, a major global agricultural pest transmitting over 200 plant viruses.
Huiwen Tan, Xichao Hu, Jinghao Hu, Wei Xu, Qianwen Wang, Xiaolan Liu, Lei Guo   +6 more
openaire   +2 more sources

Population-scale variability of the human UDP-glycosyltransferase gene family

Journal of Genetics and Genomics
Human UDP-glycosyltransferases (UGTs) are responsible for the glycosylation of a wide variety of endogenous substrates and commonly prescribed drugs. Different genetic polymorphisms in UGT genes are implicated in interindividual differences in drug response and cancer risk.
Daianna González-Padilla, Mahamadou D. Camara, Volker M. Lauschke, Yitian Zhou   +3 more
openaire   +2 more sources

UGT708S6 from Dendrobium catenatum, catalyzes the formation of flavonoid C-glycosides

BMC Biotechnology
Background Dendrobium catenatum is a perennial herb of the genus Dendrobium orchidaceae. It has been known as “Golden Grass, Soft Gold” since ancient times with effects of strengthening the body, benefiting the stomach, generating body fluid, nourishing ...
Luyao Yu, Kun He, Yu Wu, Kai Hao, Yun Wang, Jinbo Yao, Yuxue Zhao, Qiaoxian Yu, Yanghui Shen, Mengxuan Chen, Ke Xu, Xinfeng Zhang, Lei Zhang   +12 more
doaj   +1 more source

Efficient production of hydroxysalidroside in Escherichia coli via enhanced glycosylation and semi-rational design of UGT85A1

Synthetic and Systems Biotechnology
Hydroxysalidroside is an important natural phenylethanoid glycoside with broad application prospects in the food and pharmaceutical fields. However, its low concentration in plants and complex extraction hinder its production.
Xinru Wang, Lian Wang, Qihang Chen, Ke Wang, Huijing Wang, Dong Li, Song Gao, Weizhu Zeng, Jingwen Zhou   +8 more
doaj   +1 more source

Proteomics Identified UDP-Glycosyltransferase Family Members as Pro-Viral Factors for Turnip Mosaic Virus Infection in Nicotiana benthamiana. [PDF]

Viruses, 2023
Ding K, Jia Z, Rui P, Fang X, Zheng H, Chen J, Yan F, Wu G.   +7 more
europepmc   +1 more source

Recruitment of distinct UDP-glycosyltransferase families demonstrates dynamic evolution of chemical defense within Eucalyptus L'Hér. [PDF]

New Phytol, 2023
Hansen CC, Sørensen M, Bellucci M, Brandt W, Olsen CE, Goodger JQD, Woodrow IE, Lindberg Møller B, Neilson EHJ.   +8 more
europepmc   +1 more source

Substrate binding and catalytic mechanism of the Se-glycosyltransferase SenB in the biosynthesis of selenoneine

Nature Communications
Selenium is an essential multifunctional trace element in diverse organisms. The only Se-glycosyltransferase identified that catalyzes the incorporation of selenium in selenoneine biosynthesis is SenB from Variovorax paradoxus.
Wei Huang, Jun Song, Tianxue Sun, Yue He, Xiang Li, Zixin Deng, Feng Long   +6 more
doaj   +1 more source

Genome-wide identification, characterization, and expression analysis of UDP-glycosyltransferase genes associated with secondary metabolism in alfalfa (Medicago sativa L.). [PDF]

Front Plant Sci, 2022
Yu A, Jiang X, Sun Y, Hu Q, Zhu X, Kang J, Chen L, Liu L, Hao L, Yang Q, Long R, Li M.   +11 more
europepmc   +1 more source

Combinatorial metabolic engineering of Escherichia coli for de novo production of structurally defined and homogeneous Amino oligosaccharides

Synthetic and Systems Biotechnology
Amino oligosaccharides (AOs) possess various biological activities and are valuable in the pharmaceutical, food industries, and agriculture. However, the industrial manufacturing of AOs has not been realized yet, despite reports on physical, chemical ...
Jinqi Shi, Chen Deng, Chunyue Zhang, Shu Quan, Liqiang Fan, Liming Zhao   +5 more
doaj   +1 more source

Miglustat ameliorates isoproterenol-induced cardiac fibrosis via targeting UGCG

Molecular Medicine
Background Cardiac fibrosis is significant global health problem, which is associated with numerous cardiovascular diseases, and ultimately leads to the progression to heart failure.
Jing Liu, Wenqi Li, Ran Jiao, Zhigang Liu, Tiantian Zhang, Dan Chai, Lingxin Meng, Zhongyi Yang, Yuming Liu, Hongliang Wu, Xiaoting Gu, Xiaohe Li, Cheng Yang   +12 more
doaj   +1 more source