Results 91 to 100 of about 68,086 (202)

UGT85A84 Catalyzes the Glycosylation of Aromatic Monoterpenes in Osmanthus fragrans Lour. Flowers

Frontiers in Plant Science, 2019
The monoterpenes linalool and its oxides are the key aroma-active compounds in Osmanthus fragrans Lour. flowers. The glycosides of these monoterpenes accumulate throughout flowering, leading to considerable storage of potential aroma constituents that ...
Riru Zheng, Riru Zheng, Zhenyin Zhu, Zhenyin Zhu, Yanli Wang, Yanli Wang, Shiyang Hu, Shiyang Hu, Wan Xi, Wan Xi, Wei Xiao, Wei Xiao, Xiaolu Qu, Xiaolu Qu, Linlin Zhong, Linlin Zhong, Qiang Fu, Qiang Fu, Caiyun Wang, Caiyun Wang   +19 more
doaj   +1 more source

Revisiting the Molecular Roadmap for Sugar Crops: Genome Reading, Trait Writing and Variety Redesigning

Plant Biotechnology Journal, EarlyView.
ABSTRACT Sugar crops, including but not limited to sugarcane, sugar beet, sweet sorghum and stevia, are major sources of sugar production in the world. However, conventional breeding approaches, limited by long breeding cycles, low efficiency and restricted capacity to improve complex traits in sugar crops, are increasingly insufficient to address the ...
Peilin Wang, Qibin Wu, Wenzhi Wang, Prakash Lakshmanan, Yangrui Li, Khushi Muhammad, Yuguang Wang, Youxiong Que   +7 more
wiley   +1 more source

Identification and Characterization of a Putative Kaempferol Glucosyltransferase UGT78G3 in Medicago truncatula

Plants
UDP-glycosyltransferases (UGTs) represent a large multigene family that play a central role in glycosylating a highly diverse array of natural products, underscoring their critical importance in various biological processes. However, the functional roles
Pengcheng Yin, Jianuo Cao, Jiayu Xing, Zelin Xia, Wanqiong Li, Ke Li, Xiao Meng, Geng Wang, Chunjiang Zhou   +8 more
doaj   +1 more source

Development of In Vitro and In Planta Strategies for Efficient Production of High‐Value Steviol Glycosides

Plant Biotechnology Journal, EarlyView.
ABSTRACT Steviol glycosides (SGs) are a group of sweet‐tasting diterpene glycosides found in Stevia rebaudiana. Production of high‐value SGs, Rebaudioside D (Reb D) and Reb M, is limited by inefficient conversion of Reb A to Reb D and stevioside to Reb E.
Sing Hui Leong, Benny Jian Rong Sng, Ian Kin Yuen Choi, In‐Cheol Jang   +3 more
wiley   +1 more source

Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis

Angewandte Chemie, Volume 138, Issue 25, 15 June 2026.
Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
wiley   +2 more sources

Regioselective Glycosylation of Demethylbellidifolin by Glycosyltransferase AbCGT Yields Potent Anti-Renal Fibrosis Compound

Molecules
Glycosylation serves as an effective strategy to enhance the solubility, bioavailability, and pharmacological activity of polyhydroxyphenols. In this study, we explored the glycosylation of natural and natural-inspired phenolic compounds using the ...
Limin Zeng, Shichao Cui, Xingyu Ji, Yuhong Liu, Guozhang Long, Yulan Xia, Gang Cheng, Jingya Li, Youhong Hu   +8 more
doaj   +1 more source

Methyl Jasmonate Seed Priming Mitigates the Defence‐Growth Trade‐Off and Tailors Plant Response to Specific Pests

Plant, Cell &Environment, EarlyView.
ABSTRACT Seed defence priming is emerging as a novel, cost‐efficient and environmentally safe tool for pest management. It has been proposed as a means to uncouple the defence‐growth trade‐off in plants by enhancing defence responses with minimal fitness costs, but the mechanisms underlying this role remain elusive.
Lucia Talavera‐Mateo, Adrian Sabater‐Gabriel, Alejandro Garcia, Marta Marina Perez‐Alonso, Rayko Halitschke, M. Estrella Santamaria   +5 more
wiley   +1 more source

Transcriptome and Hormone Regulations Shape Drought Stress‐Dependent Fusarium Head Blight Susceptibility in Different Barley Genotypes

Plant, Cell &Environment, EarlyView.
ABSTRACT Little is known about regulatory mechanisms that crop plants use to respond to combinations of abiotic and biotic stress. We analysed four barley genotypes under simultaneous Fusarium culmorum infection and drought stress by phenotyping for Fusarium Head Blight (FHB) disease, drought stress responses, hormone profiling and transcriptome ...
Felix Hoheneder, Christina Elisabeth Steidele, Michael Gigl, Corinna Dawid, Ralph Hückelhoven   +4 more
wiley   +1 more source

Functional characterization, structural basis, and protein engineering of a rare flavonoid 2′-O-glycosyltransferase from Scutellaria baicalensis

Acta Pharmaceutica Sinica B
Glycosylation is an important post-modification reaction in plant secondary metabolism, and contributes to structural diversity of bioactive natural products. In plants, glycosylation is usually catalyzed by UDP-glycosyltransferases.
Zilong Wang, Xueqing Du, Guo Ye, Haotian Wang, Yizhan Liu, Chenrui Liu, Fudong Li, Hans Ågren, Yang Zhou, Junhao Li, Chao He, De-An Guo, Min Ye   +12 more
doaj   +1 more source

Hyperglycaemia‐induced reactive oxygen species production in cardiac ventricular myocytes differs among mammals

The Journal of Physiology, EarlyView.
Abstract figure legend In rat and human adult ventricular myocytes, acute hyperglyceaemia (Glucose) causes increased glucose uptake (via GLUT) leading to O‐GlcNAcylation of CaMKII at Ser280, such that CaMKII activates NADPH oxidase 2 (NOX2) to increase cytosolic reactive oxygen species (ROS). That perturbs the ROS to Antioxidant (AntiOx) balance.
Shan Lu, Maria J. Baier, Risto‐Pekka Polonen, Zhandi Liao, Jody L. Martin, Kenneth S. Ginsburg, Julian Mustroph, Donald M. Bers   +7 more
wiley   +1 more source