Results 91 to 100 of about 44,652 (214)

UGT85A84 Catalyzes the Glycosylation of Aromatic Monoterpenes in Osmanthus fragrans Lour. Flowers

Frontiers in Plant Science, 2019
The monoterpenes linalool and its oxides are the key aroma-active compounds in Osmanthus fragrans Lour. flowers. The glycosides of these monoterpenes accumulate throughout flowering, leading to considerable storage of potential aroma constituents that ...
Riru Zheng, Riru Zheng, Zhenyin Zhu, Zhenyin Zhu, Yanli Wang, Yanli Wang, Shiyang Hu, Shiyang Hu, Wan Xi, Wan Xi, Wei Xiao, Wei Xiao, Xiaolu Qu, Xiaolu Qu, Linlin Zhong, Linlin Zhong, Qiang Fu, Qiang Fu, Caiyun Wang, Caiyun Wang   +19 more
doaj   +1 more source

The histone deacetylase inhibitor, suberoylanilide hydroxamic acid, restores blood–brain barrier integrity in a human stem cell‐based model of ischaemic stroke

British Journal of Pharmacology, Volume 183, Issue 19, Page 5791-5812, October 2026.
Ischaemic stroke is characterised by acute cerebrovascular occlusion and blood–brain barrier (BBB) breakdown. Our results indicated that the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) ameliorated the loss of BBB integrity, changed the morphology of brain endothelial cells, increased the level of basement membrane and ...
Anikó Szecskó, Koppány Párdi, Zuhao Cui, Gergő Porkoláb, Zsófia Hoyk, Csilla Kovács, Janet F. Adegbite, Virág Fodor, Nárcisz M. Cser, László Dér, Krisztina Nagy, Csilla Sajben, Roland Tengölics, Mária A. Deli, Szilvia Veszelka   +14 more
wiley   +1 more source

UDP-MurNAc-pentapeptide synthesis.

, 2018
(A) The principle of the reaction where the amine group of the lysine in UDP-MurNAc-pentapeptide was converted to azide through diazo transfer. (B) Structure of dansyl alkyne.
Yao Liu (173014), Stefan Scheidelaar (1875211), J. Antoinette Killian (469726), Michal Heger (3574472), Elisabete C. C. M. Moura (5931875), Eefjan Breukink (154126), Jonas M. Dörr (5931878), Maarten R. Egmond (2095573), Tamimount Mohammadi (80891)   +8 more
core   +1 more source

Regioselective Glycosylation of Demethylbellidifolin by Glycosyltransferase AbCGT Yields Potent Anti-Renal Fibrosis Compound

Molecules
Glycosylation serves as an effective strategy to enhance the solubility, bioavailability, and pharmacological activity of polyhydroxyphenols. In this study, we explored the glycosylation of natural and natural-inspired phenolic compounds using the ...
Limin Zeng, Shichao Cui, Xingyu Ji, Yuhong Liu, Guozhang Long, Yulan Xia, Gang Cheng, Jingya Li, Youhong Hu   +8 more
doaj   +1 more source

UDP-glycosyltransferase family in Haemonchus contortus: Phylogenetic analysis, constitutive expression, sex-differences and resistance-related differences

International Journal for Parasitology: Drugs and Drug Resistance, 2018
UDP-glycosyltransferases (UGT), catalysing conjugation of UDP-activated sugar donors to small lipophilic chemicals, are widespread in living organisms from bacteria to fungi, plant, or animals.
Petra Matoušková, Lenka Lecová, Roz Laing, Diana Dimunová, Heiko Vogel, Lucie Raisová Stuchlíková, Linh Thuy Nguyen, Pavlína Kellerová, Ivan Vokřál, Jiří Lamka, Barbora Szotáková, Marián Várady, Lenka Skálová   +12 more
doaj   +1 more source

Transcriptomic and proteomic signatures underlying nymphal adaptation and foam production in the forage pest Mahanarva spectabilis

Insect Molecular Biology, Volume 35, Issue 5, Page 556-575, October 2026.
RNA‐seq and Batelli gland proteomics of fifth‐instar Mahanarva spectabilis nymphs reveal transcripts and proteins associated with xylem feeding, foam production and environmental interaction. Functional annotation identified genes involved in osmoregulation, detoxification, chemosensation and stress responses, while proteomic analysis confirmed ...
Monique da Silva Bonjour, Angelo José Rinaldi, Eulálio Gutemberg Dias dos Santos, Gabriely Teixeira Bhering Faria, Ana Márcia Escocard de Azevedo Manhães, Jorge Fernando Pereira, Alexander Machado Auad, Maria Goreti de Almeida Oliveira, Humberto Josué de Oliveira Ramos   +8 more
wiley   +1 more source

Thermostable glycosyltransferase variants

, 2023
The present invention concerns glycosyltransferase enzyme mutants having improved half-lives and thermal stability compared to the parent enzyme UDP-glycosyltransferase (PtUGT) from the indigo producing plant Polygonum tinctorium/Persicaria tinctoria ...
Welner, Ditte Hededam, Leggio, Leila Lo, Costoya, Gonzalo Nahuel Bidart   +2 more
core  

Methyl Jasmonate Seed Priming Mitigates the Defence‐Growth Trade‐Off and Tailors Plant Response to Specific Pests

Plant, Cell &Environment, Volume 49, Issue 10, Page 7558-7574, October 2026.
ABSTRACT Seed defence priming is emerging as a novel, cost‐efficient and environmentally safe tool for pest management. It has been proposed as a means to uncouple the defence‐growth trade‐off in plants by enhancing defence responses with minimal fitness costs, but the mechanisms underlying this role remain elusive.
Lucia Talavera‐Mateo, Adrian Sabater‐Gabriel, Alejandro Garcia, Marta Marina Perez‐Alonso, Rayko Halitschke, M. Estrella Santamaria   +5 more
wiley   +1 more source

Functional characterization, structural basis, and protein engineering of a rare flavonoid 2′-O-glycosyltransferase from Scutellaria baicalensis

Acta Pharmaceutica Sinica B
Glycosylation is an important post-modification reaction in plant secondary metabolism, and contributes to structural diversity of bioactive natural products. In plants, glycosylation is usually catalyzed by UDP-glycosyltransferases.
Zilong Wang, Xueqing Du, Guo Ye, Haotian Wang, Yizhan Liu, Chenrui Liu, Fudong Li, Hans Ågren, Yang Zhou, Junhao Li, Chao He, De-An Guo, Min Ye   +12 more
doaj   +1 more source

Biochemical and molecular characterization of a flavonoid 3-O-glycosyltransferase responsible for anthocyanins and flavonols biosynthesis in Freesia hybrida

Frontiers in Plant Science, 2016
The glycosylation of flavonoids increases their solubility and stability in plants. Flowers accumulate anthocyanidin and flavonol glycosides which are synthesized by UDP-sugar flavonoid glycosyltransferases (UFGTs).
Wei eSun, Wei eSun, Lingjie eLiang, Xiangyu eMeng, Yueqing eLi, Fengzhan eGao, Xingxue eLiu, Shucai eWang, Xiang eGao, Xiang eGao, Li eWang   +10 more
doaj   +1 more source