Results 21 to 30 of about 16,272 (234)

PBPK Modeling as a Tool for Predicting and Understanding Intestinal Metabolism of Uridine 5′-Diphospho-glucuronosyltransferase Substrates

Pharmaceutics, 2021
Uridine 5′-diphospho-glucuronosyltransferases (UGTs) are expressed in the small intestines, but prediction of first-pass extraction from the related metabolism is not well studied.
Micaela B. Reddy, Michael B. Bolger, Grace Fraczkiewicz, Laurence Del Frari, Laibin Luo, Viera Lukacova, Amitava Mitra, Joyce S. Macwan, Jim M. Mullin, Neil Parrott, Aki T. Heikkinen   +10 more
doaj   +1 more source

La Unión General de Trabajadores (UGT) y la Confederación Francesa Democrática del Trabajo (CFDT): nuevas ejecutivas, nuevo socio sindical en Francia (1971-1978)

Hispania, 2018
La opción sindical defendida por la Unión General de Trabajadores (UGT) a lo largo del exilio consistió en privilegiar el trabajo en las grandes instituciones sindicales del mundo occidental y mantener una presencia casi testimonial en España.
Bruno Vargas
doaj   +1 more source

Species differences in phenobarbital-mediated UGT gene induction in rat and human liver microtissues

Toxicology Reports, 2021
Species differences in hepatic metabolism of thyroxine (T4) by uridine diphosphate glucuronosyl transferase (UGT) and susceptibility to thyroid hormone imbalance could underlie differences in thyroid carcinogenesis caused by hepatic enzyme inducers in ...
Simon Plummer, Bobby Beaumont, Matthew Elcombe, Stephanie Wallace, Jayne Wright, Elizabeth F Mcinnes, Richard A Currie, David Cowie   +7 more
doaj   +1 more source

Internacionalistas entre la revolución y el fascismo: la Unión General de Trabajadores en el mundo (1919-1936)

Hispania, 2018
El artículo analiza la política exterior que desarrolló UGT de España, en el marco del internacionalismo obrero, durante el periodo de entreguerras.
Manuela Aroca Mohedano
doaj   +1 more source

La acción de los Ugetistas en la Organización Internacional del Trabajo: contrarrestar el sindicalismo franquista en el mundo (1969-1976)

Hispania, 2018
La intervención de los socialistas europeos y de los sindicatos tuvo un impacto favorable en el establecimiento de una oposición enérgica y en la deslegitimación del régimen de Franco, tanto en el interior como en el exterior de España.
Enrique Berzal de la Rosa
doaj   +1 more source

Kinetic and Kinematic Analysis of Gait Termination: A Comparison between Planned and Unplanned Conditions

Applied Sciences, 2023
Purpose: Gait termination (GT) is the transition from steady-state walking to a complete stop, occurring under planned gait termination (PGT) or unplanned gait termination (UGT) conditions.
Chae-Won Kwon, Seong-Ho Yun, Dong-Kyun Koo, Jung-Won Kwon   +3 more
doaj   +1 more source

Dos reformas que recuperan derechos, reducen desigualdades, y garantizan el futuro de las pensiones sin recortes

Oñati Socio-Legal Series
La simple pretensión de este artículo es dar a conocer las Reformas de Pensiones de España que han sido fruto del Acuerdo de Diálogo Social en los últimos años, para acercarlo a los trabajadores y trabajadoras, a la ciudadanía en general, de manera ...
Cristina Estévez Navarro
doaj   +1 more source

The evolution of UDP-glycosyl/glucuronosyltransferase 1E (UGT1E) genes in bird lineages is linked to feeding habits but UGT2 genes is not. [PDF]

PLoS ONE, 2018
UDP-glycosyltransferase (UGT) catalyzes the transfer of glycosyl groups (e.g., glucuronic acid) to exogenous or endogenous chemicals and plays an important role in conjugation reactions.
Yusuke K Kawai, Yoshinori Ikenaka, Mayumi Ishizuka, Akira Kubota   +3 more
doaj   +1 more source

Genome-Wide Analysis of UGT Genes in Petunia and Identification of PhUGT51 Involved in the Regulation of Salt Resistance

Plants, 2022
UDP-glycosyltransferase (UGT) plays an essential role in regulating the synthesis of hormones and secondary metabolites in plants. In this study, 129 members of the Petunia UGT family were identified and classified into 16 groups (A–P) based on ...
Lili Dong, Ziyan Tang, Tianyin Yang, Fuling Hao, Xinyi Deng   +4 more
doaj   +1 more source

Tandem Duplication‐Driven Neofunctionalization of UDP‐Glycosyltransferases Shapes the Diversification of Triterpenoid Saponins in the Cucurbitaceae

Advanced Science, EarlyView.
We present a chromosome‐level genome assembly of Siraitia grosvenorii and, through comparative genomics, uncover a conserved UGT73 tandem array driving triterpenoid saponin diversification in Cucurbitaceae. Crystalized SgUGT73AM30 further reveals the regioselectivity mechanism underlying its catalytic activity.
Guangyi Wang, Mengmeng Li, Xuehui Dai, Yanchen Zhang, Yuhan Wu, Zhaotao Yan, Chenfei Tian, Hongkai Fan, Haili Liu, Xiaowei Zhang, Yiming Yang, Jiayu Lu, Yuwei Sun, Yong Wang   +13 more
wiley   +1 more source