Results 41 to 50 of about 51,776 (205)

Physiologically Based Pharmacokinetic Modeling of Oxcarbazepine to Characterize Its Disposition in Children with Obesity

The Journal of Clinical Pharmacology, EarlyView.
Abstract Oxcarbazepine (OXC) is a second‐generation antiseizure medication, effective through its active metabolite, 10‐mono‐hydroxy derivative (MHD). OXC is used as adjunctive therapy for focal‐onset and primary generalized tonic–clonic seizures, with recommended dosing based on age and body weight.
Patricia D. Maglalang, Jaydeep Sinha, Victόria Etges Helfer, Andrea Edginton, Kanecia Zimmerman, Chi Dang Hornik, William J. Muller, Mobeen Rathore, Daniel K. Benjamin Jr., Jia‐Yuh Chen, Ravinder Anand, Daniel Gonzalez, the Best Pharmaceuticals for Children Act – Pediatric Trials Network Steering Committee   +12 more
wiley   +1 more source

EFEKTIVITAS AKAD PEMBIAYAAN BAI’ AL- WAFA PADA BAITUL MAAL WAT TAMWIL

Arena Hukum, 2017
Akad Bai' al-Wafa is a complementary in the form of loans granted by Baitul Maal Wat Tamwil (BMT) UGT Sidogiri Branch Wonokerto as a buyer (creditor) to its members (sellers) that need funding on condition that the goods sold can be bought back by the ...
Kudus Kudus, Naghfir Naghfir
doaj   +1 more source

Genome-wide analysis of UGT gene family identified key gene for the biosynthesis of bioactive flavonol glycosides in Epimedium pubescens Maxim.

Synthetic and Systems Biotechnology, 2022
Epimedium pubescens Maxim. is a well-known traditional Chinese medicinal herb with flavonol glycosides as the major pharmaceutically active compounds. UDP-glycosyltransferases (UGTs) are a group of enzymes responsible for the glycosylation of flavonoid ...
Yu Yao, Jiajun Gu, Yanjiao Luo, Yuanyue Wang, Yongzhen Pang, Guoan Shen, Baolin Guo   +6 more
doaj   +1 more source

Modifying Antibiotic Activity of Synthetic Thiadiazine Analogs Against MDR Bacteria and ADMET Analysis

ChemistryOpen, EarlyView.
The study demonstrated that thidiazine compounds potentiated the action of antibiotics. The compounds associated with norfloxacin against S. aureus showed greater significance in relation to the other medications. The indiscriminate use of antibiotics has led to the selection of resistant bacterial strains, significantly reducing the effectiveness of ...
João Arthur de Oliveira Borges, Priscilla Ramos Freitas, Isaac Moura Araújo, Ray Silva de Almeida, Igor José dos Santos Nascimento, João Xavier de Araújo‐Júnior, Edeildo Ferreira da Silva‐Júnior, Thiago Mendonça de Aquino, Francisco Jaime Bezerra Mendonça Junior, Emmanuel Silva Marinho, Hélcio Silva dos Santos, Radosław Kowalski, Grażyna Kowalska, Henrique Douglas Melo Coutinho, Saulo Relison Tintino, Ana Carolina Justino de Araújo   +15 more
wiley   +1 more source

Propuesta sindical prioritaria

Política y Sociedad, 1990
Sin ...
UGT-CC.OO. Ugt-cc.oo.
doaj  

Genome-wide analysis of family-1 UDP glycosyltransferases (UGT) and identification of UGT genes for FHB resistance in wheat (Triticum aestivum L.)

BMC Plant Biology, 2018
Background Fusarium head blight (FHB), a devastating disease in wheat worldwide, results in yield loses and mycotoxin, such as deoxynivalenol (DON), accumulation in infected grains.
Yi He, Dawood Ahmad, Xu Zhang, Yu Zhang, Lei Wu, Peng Jiang, Hongxiang Ma   +6 more
doaj   +1 more source

Relevance of Health-Related Hashtags on Twitter: A Text Mining Approach [PDF]

, 2020
BACKGROUND Social media platforms facilitate user interaction and impact decision making. Users prefer to use hashtags while sharing posts. Knowing the sentiment towards diabetes, bloodpressure, and obesity is fundamental to understanding the impact of ...
Dalal, Mauli, Osei-Bryson, Kweku-Muata
core   +1 more source

Physiologically based pharmacokinetic modeling and simulation of topiramate in populations with renal and hepatic impairment and considerations for drug–drug interactions

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 510-522, March 2025.
Abstract Topiramate (TPM) is a broad‐spectrum antiepileptic drug (AED) commonly prescribed for approved and off‐label uses. Routine monitoring is suggested for clinical usage of TPM in special population due to its broad side effect profile. Therefore, it is crucial to further explore its pharmacokinetic characteristics.
Shuqing Chen, Chaozhuang Shen, Yuchen Tian, Yuhe Peng, Jing Hu, Haitang Xie, Ping Yin   +6 more
wiley   +1 more source

Elementos de desarrollo territorial en la Provincia de Arauco

Urbano, 2005
La Región del Bío-Bío ha desarrollado con el fin de articular la inversión pública y hacerla más eficiente, una Estrategia Territorial, llamada Programa de Desarrollo Territorial (PDT), la que está en sintonía con las necesidades propias de cada ...
Ximena Oliva Aravena
doaj  

The UDP-glucosyltransferase multigene family in Bombyx mori

BMC Genomics, 2008
Background Glucosidation plays a major role in the inactivation and excretion of a great variety of both endogenous and exogenous compounds. A class of UDP-glycosyltransferases (UGTs) is involved in this process.
Lu Cheng, Dai Fang-Yin, Liu Zeng-Hu, Zhang Ze, Chai Chun-Li, Huang Fei-Fei, Xiang Zhong-Huai   +6 more
doaj   +1 more source