Results 61 to 70 of about 51,776 (205)

Minor Contribution of UGT1A1 Inhibition to Atazanavir‐Related Bilirubin Elevation Supported by Conservative PBPK Modeling and Clinical Data

Clinical Pharmacology &Therapeutics, EarlyView.
Jin Dong, Pradeep Sharma, Rasha Emara, Derek Cheung, Weifeng Tang, Diansong Zhou, David W. Boulton, Mats Någård, Miki S. Park   +8 more
wiley   +1 more source

GeARF5/GeIAA33‐GeSWEET14 module balances the secondary metabolic biosynthesis to increase the yield and quality in Gastrodia elata

Journal of Integrative Plant Biology, EarlyView.
Auxin signaling regulates the formation of vegetative propagation corms in Gastrodia elata by regulating sugar‐acid interconversion, which in turn regulates polysaccharide and starch biosynthesis as well as biosynthesis of the bioactive metabolite gastrodin.
Qun Liu, Zhiqing Wu, Yugang Gao, Yue Xu, Pu Zang, Xinyu Yang, Yan Zhao, Pan Liao, Benoît Boachon, Guoyin Kai   +9 more
wiley   +1 more source

Analisis Akuntansi Pembiayaan Mudarabah Berdasarkan PSAK 105 Pada BMT UGT Nusantara Cabang Pembantu Tayan

Aktiva
Purpose: This study aims to determine the management of mudarabah financing and to analyze the accounting treatment of mudarabah financing at BMT UGT Nusantara Tayan Sub-Branch based on PSAK 105.
Dini Lestary, Risatri Hayatunisa
doaj   +1 more source

In silico prediction of UGT-mediated metabolism in drug-like molecules via graph neural network

Journal of Cheminformatics, 2022
UDP-glucuronosyltransferases (UGTs) have gained increasing attention as they play important roles in the phase II metabolism of drugs. Due to the time-consuming process and high cost of experimental approaches to identify the metabolic fate of UGT ...
Mengting Huang, Chaofeng Lou, Zengrui Wu, Weihua Li, Philip W. Lee, Yun Tang, Guixia Liu   +6 more
doaj   +1 more source

Recombinant expression and functional characterisation of regiospecific flavonoid glucosyltransferases from Hieracium pilosella L. [PDF]

, 2009
Five glucosyltransferases were cloned by RT-PCR amplification using total RNA from Hieracium pilosella L. (Asteraceae) inflorescences as template. Expression was accomplished in Escherichia coli, and three of the HIS-tagged enzymes, UGT90A7, UGT95A1, and
Martens, S., Matern, U., Moco, S.I.A., Vervoort, J.J.M., Witte, S.   +4 more
core   +2 more sources

The Rhus chinensis Genome Provides Insights Into Tannin, Flavonoid Biosynthesis, and Glandular Trichome Development

Plant Biotechnology Journal, EarlyView.
ABSTRACT The “salt tree”, Rhus chinensis, holds significant economic and medicinal value due to its ability to produce Galla chinensis (Chinese gall/gallnut), a plant‐derived medicinal material used in both traditional Chinese and modern medicine that is rich in tannins and flavonoids. It is also renowned for its remarkable stress tolerance.
Zhaogeng Lu, Helin Zou, Jiawen Cui, Tongfei Wang, Lingyu Ma, Shixiong Ren, Yiwei Cao, Xi Zhang, Zixi Chen, Hongyan Bao, Ling Zhu, Yaning Cui, Ruili Li, Xiuyan Yang, Qikun Zhang, Zhili Wang, Wangxiang Zhang, Li Wang, Jinxing Lin, Biao Jin   +19 more
wiley   +1 more source

The resolution of case conflicts : a pilot study [PDF]

, 2004
This paper reports the results of a pilot study on the resolution of case conflicts in German free relative constructions. Section 1 gives a brief introduction into the phenomenon, section 2 presents the experiment and its results, section 3 ends the ...
Frisch, Stefan, Vogel, Ralf
core  

Chlamydia trachomatis from Australian Aboriginal people with trachoma are polyphyletic composed of multiple distinctive lineages. [PDF]

, 2016
Chlamydia trachomatis causes sexually transmitted infections and the blinding disease trachoma. Current data on C. trachomatis phylogeny show that there is only a single trachoma-causing clade, which is distinct from the lineages causing urogenital tract
Andersson, Patiyan, Asche, L Valerie, Clarke, Ian N, Cutcliffe, Lesley T, Douglas, Fiona P, Giffard, Philip M, Hadfield, James, Harris, Simon R, Hutton, Susan I, Mathews, John D, O'Neill, Colette, Sarovich, Derek S, Smith, Helena MB Seth, Thomson, Nicholas R, Tong, Steven YC   +14 more
core   +1 more source

CsYABBY1 and CsMYB114 Enhance Acquired Drought Tolerance by Mediating Flavonoid Biosynthesis in Camellia sinensis

Plant Biotechnology Journal, EarlyView.
ABSTRACT Drought priming is a critical agronomic strategy for enhancing plant drought tolerance, yet the optimal priming intensity and transcriptional regulatory mechanisms underlying subsequent drought responses in the tea plant (Camellia sinensis) remain poorly characterised.
Caiyun Tian, Chengzhe Zhou, Shengjing Wen, Cheng Zhang, Anru Zheng, Lele Jiang, Niannian Yang, Zhuo Tang, Xiaowen Hu, Zhendong Zhang, Jiaxin Fang, Zhong Wang, Yuqiong Guo   +12 more
wiley   +1 more source

Engineering of the Flavone Rutinoside Biosynthetic Pathway Enables Production of Diosmin, a Venoactive Compound in Solanum lycopersicum and Nicotiana tabacum

Plant Biotechnology Journal, EarlyView.
ABSTRACT Diosmin is often used as a dietary supplement, and it is sometimes used to make phlebotropic drugs for venous diseases. Traditionally, diosmin is obtained by the dehydrogenation of the flavanone glycoside hesperidin through chemical semisynthesis.
Qianle Zhang, Qingwen Wu, Wenjing Shi, Yinai Deng, Ruoting Zhan, Dongming Ma   +5 more
wiley   +1 more source