Results 1 to 10 of about 17,787 (143)

Grape Lipidomics: An Extensive Profiling thorough UHPLC-MS/MS Method [PDF]

open access: yesMetabolites, 2021
Lipids play many essential roles in living organisms, which accounts for the great diversity of these amphiphilic molecules within the individual lipid classes, while their composition depends on intrinsic and extrinsic factors.
Domenico Masuero   +7 more
doaj   +4 more sources

UHPLC-MS/MS-based untargeted metabolite profiling of Lyme neuroborreliosis

open access: yesScientific Reports
The diagnosis of Lyme neuroborreliosis (LNB) requires the demonstration of intrathecal synthesis of Borrelia antibodies in a patient’s cerebrospinal fluid (CSF), which involves the invasive procedure of a lumbar puncture.
Ilari Kuukkanen   +8 more
doaj   +4 more sources

A Strategy for Identification and Structural Characterization of Compounds from Plantago asiatica L. by Liquid Chromatography-Mass Spectrometry Combined with Ion Mobility Spectrometry

open access: yesMolecules, 2022
Plantago asiatica L. (PAL) as a medicinal and edible plant is rich in chemical compounds, which makes the systematic and comprehensive characterization of its components challenging.
Hongxue Gao   +5 more
doaj   +1 more source

High Throughput UHPLC-MS-Based Lipidomics Using Vacuum Jacketed Columns [PDF]

open access: yesJournal of Proteome Research, 2021
Reversed-phase UHPLC-MS is extensively employed for both the profiling of biological fluids and tissues to characterize lipid dysregulation in disease and toxicological studies. With conventional LC-MS systems the chromatographic performance and throughput are limited due to dispersion from the fluidic connections as well as radial and longitudinal ...
Robert S. Plumb   +7 more
openaire   +4 more sources

Dynamic profiling of intact glucosinolates in radish by combining UHPLC-HRMS/MS and UHPLC-QqQ-MS/MS

open access: yesFrontiers in Plant Science, 2023
Glucosinolates (GSLs) and their degradation products in radish confer plant defense, promote human health, and generate pungent flavor. However, the intact GSLs in radish have not been investigated comprehensively yet.
Chenghuan Yan   +14 more
doaj   +1 more source

Determination of Antiviral Drugs and Their Metabolites Using Micro-Solid Phase Extraction and UHPLC-MS/MS in Reversed-Phase and Hydrophilic Interaction Chromatography Modes

open access: yesMolecules, 2021
Two new ultra-high performance liquid chromatography (UHPLC) methods for analyzing 21 selected antivirals and their metabolites were optimized, including sample preparation step, LC separation conditions, and tandem mass spectrometry detection.
Luboš Fical   +8 more
doaj   +1 more source

Recent Developments Toward Integrated Metabolomics Technologies (UHPLC-MS-SPE-NMR and MicroED) for Higher-Throughput Confident Metabolite Identifications

open access: yesFrontiers in Molecular Biosciences, 2021
Metabolomics has emerged as a powerful discipline to study complex biological systems from a small molecule perspective. The success of metabolomics hinges upon reliable annotations of spectral features obtained from MS and/or NMR. In spite of tremendous
Rajarshi Ghosh   +11 more
doaj   +1 more source

Probing the polar metabolome by UHPLC-MS

open access: yesTrAC Trends in Analytical Chemistry, 2023
Metabolomics is an interdisciplinary field with applications in many areas. Analytes include metabolites involved in pathways such as glycolysis, amino acid metabolism, the Krebs cycle, etc. However, the metabolites involved in these biosynthetic pathways are typically highly polar molecules, which represent a major challenge for chromatographic ...
Artemis Lioupi   +6 more
openaire   +3 more sources

Chronic dietary intake of enniatin B in broiler chickens has low impact on intestinal morphometry and hepatic histology, and shows limited transfer to liver tissue [PDF]

open access: yes, 2018
The Fusarium mycotoxin enniatin B (ENN B) is a so-called emerging mycotoxin frequently contaminating poultry feed. To investigate the impact of chronic ENN B exposure on animal health, broiler chickens were fed either a diet naturally contaminated with ...
Antonissen, Gunther   +5 more
core   +8 more sources

Chemotaxonomic Markers for the Leaf Buds of Common Finnish Trees and Shrubs: A Rapid UHPLC MS Fingerprinting Tool for Species Identification

open access: yesMolecules, 2022
In this study, a chemotaxonomic tool was created on the basis of ultra-high-performance liquid chromatography–mass spectrometry (UHPLC–MS) for the identification of 13 common Finnish deciduous trees and shrubs from their leaf bud metabolites.
Marianna Manninen   +2 more
doaj   +1 more source

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