Results 141 to 150 of about 51,926 (282)

Deciphering Branched Galactomannan Structures via Multistage Ion Mobility MS and MSn Fragmentation (Multistage IMSn)

open access: yesRapid Communications in Mass Spectrometry, EarlyView.
ABSTRACT Rationale Hemicelluloses are abundant carbohydrate components in plant cell walls. They play a crucial structural role in binding cellulose microfibrils, in addition to other biological functions. Their high structural variability directly influences their biological properties, making it important to establish a structure–function ...
Rania Benazza   +3 more
wiley   +1 more source

Mesoporous Silica Nanoparticles‐Based Formulations for Enhanced Oral Delivery of Peptide Drugs: A Case Study on Insulin

open access: yesSmall, EarlyView.
This work explores the tailored functionalization of mesoporous silica nanoparticles (MSN) to improve the oral delivery of insulin, as a case study. Insulin confinement within silica mesopores increased drug solubility, and co‐formulation with succinylated β‐lactoglobulin yielded pH‐responsive tablets that limited gastric release and proteolysis, while
Claudia Iriarte‐Mesa   +14 more
wiley   +1 more source

Multistressor Interaction of Perfluorooctane Sulfonate (PFOS) and Temperature in Two Estuarine Fish Species, Red Drum (Sciaenops ocellatus) and Sheepshead Minnow (Cyprinodon variegatus)

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Perfluorooctane sulfonate (PFOS), a perfluoroalkyl substance (PFAS), is characterized by a long, fluorinated carbon chain which makes it ideal for oil‐ and water‐repellent products but detrimental for the environment, where it persists and accumulates in organisms.
Anna L. Thornton   +5 more
wiley   +1 more source

Determinación de Benznidazol en orina humana mediante UHPLC-MS/MS

open access: yes, 2013
Fil: Cerutti, Estela Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Luis. Instituto de Química de San Luis. Universidad Nacional de San Luis. Facultad de Química, Bioquímica y Farmacia.
Martinez, Noelia Anabel   +4 more
openaire   +1 more source

Synergistic and Antagonistic Effects of Chemical Pollutants and Parasitic Fungi on Cyanobacterial Metabolism

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Freshwater ecosystems are increasingly impacted by anthropogenic pollutants, including the widely used herbicide metolachlor (MET) and cigarette butt (CB) litter. Parasites represent an additional biotic stressor that can modulate pollutant effects on their hosts.
Erika Berenice Martínez‐Ruiz   +3 more
wiley   +1 more source

UHPLC-MS/MS for Antipsychotic Drug Monitoring: A Systematic Review of Clinical and Analytical Performance. [PDF]

open access: yesJ Clin Med
Băcilă CI   +9 more
europepmc   +1 more source

Integrating mass spectrometry and systems biology for the modernization of natural medicines: From deciphering chemical complexity to holistic efficacy assessment

open access: yesVIEW, EarlyView.
This review explores how mass spectrometry is transforming research in natural medicines, with Traditional Chinese medicine (TCM) as a primary exemplar. It details the application of advanced mass spectrometry in chemical analysis, the development of comprehensive quality control methods, and systematic research on the targeted mechanisms of single ...
Yudian Xu   +7 more
wiley   +1 more source

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