Results 51 to 60 of about 51,926 (282)

Determination of Tranquilizers in Swine Urine by Ultra-High-Performance Liquid Chromatography-Tandem Mass Spectrometry

Molecules, 2018
A rapid, reliable, and sensitive method was developed for the determination of ten tranquilizers in swine urine. Sample preparation was based on solid-phase extraction, which combined isolation of the compounds and sample cleanup in a single step ...
Yingyu Wang, Xiaowei Li, Yuebin Ke, Chengfei Wang, Yuan Zhang, Dongyang Ye, Xue Hu, Lan Zhou, Xi Xia   +8 more
doaj   +1 more source

Comparative Investigation of the Differences in Chemical Compounds between Raw and Processed Mume Fructus Using Plant Metabolomics Combined with Chemometrics Methods

Molecules, 2022
Mume Fructus is a well-known herbal medicine and food with a long history of processing and application. Different processing methods impact the intrinsic quality of Mume Fructus.
Songrui Wang, Shujie Wei, Yameng Zhu, Mengmeng Zhang, Xiunan Cao, Yanxu Chang, Huizi Ouyang, Jun He   +7 more
doaj   +1 more source

Amino acid analysis by UHPLC-MS/MS v1

, 2018
A method allowing the simultaneous quantitation of 21 amino acids in dry leaf tissue using liquid chromatography coupled with tandem mass spectrometry (UHPLC-MS/MS) in multiple reaction monitoring (MRM) mode.
Victoria Florencio Ortiz, Susana Sellés-Marchart, Jose L. Casas   +2 more
openaire   +1 more source

KDM4A Erases the H3R17me2a Mark, Facilitating Chromosome Condensation

Advanced Science, EarlyView.
This study reveals a reversible histone modification switch governing chromosome condensation during mitosis. PKCα‐activated KDM4A removes H3R17me2a, permitting Suv39h1‐driven H3K9me3 deposition. This epigenetic transition recruits the chromosomal passenger complex and triggers Aurora B‐dependent H3S10 phosphorylation, coordinating chromatin remodeling
Yena Cho, Jee Won Hwang, Gyu Hwan Hyun, Sangkyu Lee, Dae‐Geun Song, Su‐Nam Kim, Yong Kee Kim   +6 more
wiley   +1 more source

Ufmylation‐Deficient DDRGK1 Ameliorates Obesity by Inhibiting FASN‐Mediated Adipocyte Lipogenesis

Advanced Science, EarlyView.
DDRGK1 regulates de novo lipogenesis via stabilization of fatty acid synthase (FASN). DDRGK1‐mediated UFMylation of FASN prevents its ubiquitin–proteasomal degradation. Reduced DDRGK1 expression or mutation at the key UFMylation site enhances FASN degradation and suppresses fatty acid synthesis (FAS), resulting in smaller adipocytes and improved ...
Yin Li, Tangjun Zhou, Xiao Yang, Kewei Rong, Xiankun Cao, Lei Shi, Xin Wang, Hongjin Wan, Lei Cui, Kexin Liu, Tong Xing, Hang Zhang, Chen Zhao, Tingxian Guo, Peixiang Ma, Jie Zhao, An Qin   +16 more
wiley   +1 more source

Optimization of QuEChERS cleanup for quantification of γ-oryzanol in vegetable oils by UHPLC-MS/MS

Food Chemistry: X
This study was based on QuEChERS cleanup coupled with UHPLC-MS/MS for the determination of γ-oryzanol compounds in vegetable oils. Several parameters of QuEChERS and UHPLC-MS/MS were studied for purification and detection of γ-oryzanol compounds in oil ...
Shaowei Li, Yuting Yuan, Liangxiao Zhang, Fei Ma, Peiwu Li   +4 more
doaj   +1 more source

Određivanje klorogenskih kiselina pomoću UHPLC-MS/MS

, 2023
Objectives: The development and optimization of a method used for the quantitative and qualitative determination of cryptochlorogenic and neochlorogenic acid using ultra-highperformance liquid chromatography coupled with mass spectrometry (UHPLC-MS/MS), followed by the validation of the method itself to ensure the reliability of the results.
openaire   +2 more sources

Activated Platelet–Released Heat Shock Protein 90α Triggers Autophagy‐Dependent Neutrophil Extracellular Trap Formation and Amplifies Sepsis

Advanced Science, EarlyView.
HSP90α is significantly upregulated in platelets from sepsis patients, with its origin from megakaryocyte‐derived trafficking. Furthermore, activated platelets secrete HSP90α into the extracellular space in both free and exosome‐associated forms. Finally, extracellular HSP90α directly engages TLR4 on neutrophils to induce autophagy, leading to NET ...
Chengbo Wang, Maodong Leng, Chenchen Sun, Jingyu Cao, Linfei Li, Yangyang Jia, Yongshuai Han, Yuchun Liu, Yaodong Zhang, Chenglong Zhang, Yingli Men, Ningyuan Liu, Yibing Cheng, Yixia Zhang, Ya Li, Zhenlong Li, Lidan Cui, Xiangzhan Zhu   +17 more
wiley   +1 more source

A Testis‐Specific Aralkylamine N‐Acetyltransferase Regulates Dimorphic Sperm Function and Male Fertility in Moths

Advanced Science, EarlyView.
We identify a Lepidoptera‐conserved testis‐specific arylalkylamine N‐acetyltransferase (LTNAT) that governs male moth fertility via a novel mechanism. LTNAT loss disrupts eupyrene sperm mitochondrial derivatives and impairs apyrene sperm motility, offering a safe molecular target for innovative pesticides and genetic pest control.
Hao Sun, Peng‐Yi Huang, Zhi‐Ruo Zhang, Cong‐Fen Gao, Subba Reddy Palli, Shun‐Fan Wu   +5 more
wiley   +1 more source

Metabonomic Evaluation of Chronic Unpredictable Mild Stress-Induced Changes in Rats by Intervention of Fluoxetine by HILIC-UHPLC/MS. [PDF]

PLoS ONE, 2015
Hydrophilic interaction-ultra high performance liquid chromatography (HILIC-UHPLC) allows the analysis of highly polar metabolites, providing complementary information to reversed-phase (RP) chromatography.
Longshan Zhao, Zhili Xiong, Xiumei Lu, Shuning Zheng, Fang Wang, Lin Ge, Guangyue Su, Jingyu Yang, Chunfu Wu   +8 more
doaj   +1 more source