Results 81 to 90 of about 67,993 (297)

UHPLC chromatograph of EAF. [PDF]

, 2014
UHPLC chromatograph of EAF.
Amrit Pal Singh (528364), Rajbir Kaur (528363), Saroj Arora (528365), Rakesh Kumar (8432)   +3 more
core   +1 more source

RNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control

Advanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang, Chen Kan, Xinhui Yang, Yajuan Hao, Xuemin Cai, Mei Yang, Qianqian Zhang, Zhengting Wang, Ning Jiang, Lei Wang, Hua‐Bing Li, Jing Zhou   +11 more
wiley   +1 more source

UHPLC/TOF-MS method development for untargeted metabolic analysis in urine [PDF]

, 2010
UHPLC/TOF-MS method development for untargeted metabolic analysis in ...
Wormann K., 许国旺, WormannK., FeketeA., LehmannR., ForcisiS., Schmitt-KopplinP.   +6 more
core  

Rapid and comprehensive evaluation of (poly)phenolic compounds in pomegranate (punica granatum L.) juice by UHPLC-MSn [PDF]

, 2012
The comprehensive identification of phenolic compounds in food and beverages is a crucial starting point for assessing their biological, nutritional, and technological properties.
Bruni, Renato, Luca Calani, Galaverna, Gianni, Cristina García-Viguera, Mena, P., Renato Bruni, Dall'Asta, C., Calani, Luca, Crozier A, DEL RIO, Daniele, Pedro Mena, Alan Crozier, Bruni, R., MENA PARRENO, Pedro Miguel, Garcia Viguera C, García-Viguera, C., Dall'Asta, Chiara, Chiara Dall'Asta, Mena, Pedro, Gianni Galaverna, Crozier, A., Daniele Del Rio, Chiara Dall\u27Asta, Calani, L., García-Viguera, Cristina, Rio, Daniele del, Del Rio, D., Galaverna, G., Crozier, Alan   +28 more
core   +1 more source

ZDHHC9‐Mediated Palmitoylation of ACSL4 Drives Ferroptosis in Diabetes Mellitus–Induced Erectile Dysfunction

Advanced Science, EarlyView.
ABSTRACT Diabetes mellitus‐induced erectile dysfunction (DMED) is a highly prevalent complication among diabetic patients; however, its underlying pathogenic mechanisms remain incompletely understood. Metabolic disorder is a hallmark of diabetes, yet its precise contribution to DMED progression is not well defined.
Wanyang Guo, Ming Xiao, Mengjun Huang, Dongzi Peng, Ruijiang Zeng, Ruilin Liu, Yuanqiao Zhao, Zhihan Ouyang, Yulong Hong, Zexian Ding, Zhuo Xing, Hao Su, Jinxiang Wang, Wenjun Mao, Xin Jin   +14 more
wiley   +1 more source

A Comparative Study of Newly Developed HPLC-DAD and UHPLC-UV Assays for the Determination of Posaconazole in Bulk Powder and Suspension Dosage Form

Journal of Analytical Methods in Chemistry, 2014
Objective. To develop and compare HPLC-DAD and UHPLC-UV assays for the quantitation of posaconazole in bulk powder and suspension dosage form. Methods. Posaconazole linearity range was 5–50 μg/mL for both assays. For HPLC-DAD assay, samples were injected
Dalia A. Hamdy, Tarek S. Belal
doaj   +1 more source

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

Advanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang, Yi Song, Changkun Li, Yuanyuan Luo, Mingwei Shao, Feng Guo, Fangyi Wei, Xunjie Fan, Wenwen Guo, Fengmei Xu, Yanhong Sang, Dongming Zhang, Yanhong Zhou, Lianwei Wang, Zhiqiang Kang, Yingjun Yang, Chunhua Song, Yanxia Liu, Xiaojun Ma, Jiao Wang, Chong Li, Shengnan Ma, Lin Zhao, Zhi Qin, Guolan Xing, Qiubo Zhao, Jun Li, Shumin Song, Dan Zhao, Ting Huang, Qingzhu Wang, Yanyan Zhao, Guijun Qin   +32 more
wiley   +1 more source

Development and Validation of HPLC-DAD and UHPLC-DAD Methods for the Simultaneous Determination of Guanylhydrazone Derivatives Employing a Factorial Design

Molecules, 2017
Guanylhydrazones are molecules with great pharmacological potential in various therapeutic areas, including antitumoral activity. Factorial design is an excellent tool in the optimization of a chromatographic method, because it is possible quickly change
Wanessa Azevedo de Brito, Monique Gomes Dantas, Fernando Henrique Andrade Nogueira, Edeildo Ferreira da Silva-Júnior, João Xavier de Araújo-Júnior, Thiago Mendonça de Aquino, Êurica Adélia Nogueira Ribeiro, Lilian Grace da Silva Solon, Cícero Flávio Soares Aragão, Ana Paula Barreto Gomes   +9 more
doaj   +1 more source

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

Advanced Science, EarlyView.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang, Shan Zhang, Junping Bai, Xiaobing Li, Yi Han, Min Ji, Chongyi Jiang, Xiaobei Ge, Tianyu Yu, Yongying Hou, Jun Zhang, Wangting Li, Yiran Song, Jiaying Cai, Yingqun Zhou, Liwei An, Feng Wang   +16 more
wiley   +1 more source

Lipid profile migration during the tilapia muscle steaming process revealed by a transactional analysis between MS data and lipidomics data

npj Science of Food, 2021
In this work, lipid profile migration from muscle to juice during the tilapia muscle steaming process was revealed by a transactional analysis of data from ultra-high-performance liquid chromatography coupled with Q Exactive (UHPLC-QE) Orbitrap mass ...
Rui Sun, Tingting Wu, Hao Guo, Jiamin Xu, Jiahui Chen, Ningping Tao, Xichang Wang, Jian Zhong   +7 more
doaj   +1 more source