Results 131 to 140 of about 8,179,520 (254)

Summary statistics comparing MultiXcan and PrediXcan on UK Biobank.

, 2019
Summary statistics comparing MultiXcan and PrediXcan on UK Biobank.
Jiamao Zheng (6250955), Hae Kyung Im (184277), Alvaro N. Barbeira (6250949), Milton Pividori (6288911), Dan L. Nicolae (230903), Heather E. Wheeler (174954)   +5 more
core   +1 more source

Prediction of Prevalent Cardiovascular Disease Using Social, Environmental, and Behavioral Factors: A Vital Conditions Framework Approach

Chronic Diseases and Translational Medicine, EarlyView.
The Vital Conditions Framework. Graphical representation of the Vital Conditions for Health Framework with seven domains. Images used with permission from The Rippel Foundation: An Introduction to the Vital Conditions for Health and Well‐Being. https://rippel.org/events/webinar-an-introduction-to-the-vital-conditions-for-health-and-well-being/. Federal
Stephanie Kjelstrom, Richard Hass, Robert Vollbrecht, Brandon George, Sharon Larson   +4 more
wiley   +1 more source

Increased risk of hospitalization for various disorders after COVID-19 infection: A Cohort study of the UK biobank spanning over a hundred disease categories

Journal of Microbiology, Immunology and Infection
Background: COVID-19 is one of the most pressing public health issues worldwide. The sequelae of COVID-19 however remains unclear. We performed a systematic assessment of sequelae across all body systems, focusing on whether COVID-19 is associated with ...
Yong Xiang, Ruoyu Zhang, Jinghong Qiu, Hon-Cheong So   +3 more
doaj   +1 more source

Cross-tabulation of final diabetes status from UK Biobank prevalence algorithms against primary care diabetes data for linked Welsh UK Biobank participants.

, 2016
Cross-tabulation of final diabetes status from UK Biobank prevalence algorithms against primary care diabetes data for linked Welsh UK Biobank participants.
Sinead Brophy (40627), Mark Atkinson (165217), Nishi Chaturvedi (130777), Rohini Mathur (3122613), Naomi Allen (140094), Sophie V Eastwood (3122607), Simon de Lusignan (2416), Cathie Sudlow (259959), Robin Flaig (3122610)   +8 more
core   +1 more source

UMOD Genotype and Clinical Outcomes in Heart Failure Patients Treated with Loop Diuretics: A UK Biobank Pharmacogenetic Cohort Study

Clinical Pharmacology &Therapeutics, EarlyView.
Uromodulin (UMOD) regulates tubular sodium handling and modulates NKCC2, the molecular target of loop diuretics (LD). Although UMOD variants have been associated with blood pressure and hypertension, their pharmacogenetic relevance in heart failure (HF) remains unknown.
Reinhold Kreutz, Pimrapat Gebert, Jingwen Luo, Paraskevi Tassopoulou, Juliane Bolbrinker, Antonios Douros   +5 more
wiley   +1 more source

Mental Health and Well‐Being Across the Eating Disorder Spectrum—From Milder Symptoms of Disordered Eating Behaviors to Diagnosed Eating Disorders

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective This study examined differences in mental health and well‐being, risk behaviors, suicidality, and social functioning across a proposed eating disorder (ED) spectrum, ranging from no ED symptoms to clinically diagnosed EDs. Methods We examined 44,303 participants in the 18‐year follow‐up in the Danish National Birth Cohort (DNBC‐18 ...
Anne V. Aurup, Andrea Joensen, Else Marie Olsen, Nadia M. Mikkelsen, Stine Danielsen, Pernille Stemann Larsen, Katrine Strandberg‐Larsen   +6 more
wiley   +1 more source

Bidirectional Mendelian randomization reveals associations between telomere length and autoimmune diseases

Trials
Background Autoimmune diseases are a group of complex chronic illnesses that affect multiple organs or body systems. These diseases are characterized by tissue damage, impaired organ function, and increased risk of malignancies, and elevated mortality ...
Qin Jiang, Chenxi Yu, Shiben Zhu, Yang Liu, Min Ye   +4 more
doaj   +1 more source

Integrative Genomic and Functional Investigation of the Multi‐Layered Genetic Architecture Between Anorexia Nervosa and Bone Loss

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Bone loss is a severe and often irreversible complication of anorexia nervosa (AN), yet the genetic mechanisms underlying this comorbidity remain underexplored. This study focuses on constructing a comprehensive genetic architecture between AN and estimated calcaneal bone mineral density (eBMD).
Tao Han, Yuke Wang, Yixiong Dang, Rong Xiang, Yan Zeng, Sheng He, Ye Ju, Zilan Chen, Ting Liu, Zihao Li, Yuqi Pang, Wanyi Tan, Jue Xu, Jingwen Jiang, Xia Jiang   +14 more
wiley   +1 more source

Social determinants of health, accelerated biological aging, and long-term health outcomes

Nature Communications
Social determinants of health (SDHs) are the primary drivers of health inequalities, but whether biological aging plays a role in linking SDHs to health outcomes remains unclear.
Jiang Li, Jie Li, Xiaoqin Xu, Wenqi Shen, Ying Sun, Yanqi Fu, Xiao Tan, Ningjian Wang, Lu Qi, Bin Wang, Yingli Lu   +10 more
doaj   +1 more source

Comparison of PDFF and T2* methods using UK Biobank data.

, 2018
Comparison of PDFF and T2* methods using UK Biobank data.
Matteo Milanesi (3798250), Alexandre Bagur (5775014), Michael L. Gyngell (5775011), Chloe Hutton (292794), Michael Brady (494158)   +4 more
core   +1 more source