Results 61 to 70 of about 231,179 (296)

Multinuclear Magnetic Resonance Spectroscopy at Ultra-High-Field: Assessing Human Cerebral Metabolism in Healthy and Diseased States

open access: yesMetabolites, 2023
The brain is a highly energetic organ. Although the brain can consume metabolic substrates, such as lactate, glycogen, and ketone bodies, the energy metabolism in a healthy adult brain mainly relies on glucose provided via blood.
Pandichelvam Veeraiah   +1 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Hilbert Fractal Inspired Dipoles for B1+ Field Control in Ultra-High Field MRI

open access: yes, 2020
International ...
Vergara Gomez, Tania S.   +17 more
core   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Stable, intense supercontinuum light generation at 1 kHz by electric field assisted femtosecond laser filamentation in air

open access: yesLight: Science & Applications
Supercontinuum (SC) light source has advanced ultrafast laser spectroscopy in condensed matter science, biology, physics, and chemistry. Compared to the frequently used photonic crystal fibers and bulk materials, femtosecond laser filamentation in gases ...
Yaoxiang Liu   +6 more
doaj   +1 more source

Generating a tunable narrow electron beam comb via laser-driven plasma grating

open access: yesMatter and Radiation at Extremes, 2023
We propose a novel approach for generating a high-density, spatially periodic narrow electron beam comb (EBC) from a plasma grating induced by the interference of two intense laser pulses in subcritical-density plasma.
Hetian Yang   +5 more
doaj   +1 more source

Pulse repetition-rate effect on the intensity inside a femtosecond laser filament in air

open access: yesHigh Power Laser Science and Engineering, 2023
As intense, ultrashort, kHz-repetition-rate laser systems become commercially available, pulse cumulative effects are critical for laser filament-based applications. In this work, the pulse repetition-rate effect on femtosecond laser filamentation in air
Fukang Yin   +8 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Ultra-fast polarization of a thin electron layer in the rotational standing-wave field driven by double ultra-intense laser pulses

open access: yesNew Journal of Physics, 2022
We explore radiative polarization of electrons in a standing-wave formed by two circularly-polarized laser pulses irradiating a thin layer. Here the electron radiative spin dynamics in external electromagnetic fields is described by the generalized ...
Qianqian Han   +4 more
doaj   +1 more source

Optimised techniques for ultra-high field functional magnetic resonance imaging

open access: yes, 2022
© 2022 Didi ChiFunctional Magnetic Resonance Imaging (fMRI) has become broadly used to study brain function since its invention in the late 20th century, applicable to both the study of healthy controls and patient groups.
Chi, Didi
core  

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