Results 241 to 250 of about 119,803 (296)

Structural Basis for Trivalent Cross‐Linking of a Patient‐Derived IgE Antibody by the Major Peanut Allergen Ara h 2.0201

open access: yesAllergy, EarlyView.
Graphical The crystal structure of a major peanut allergen Ara h 2.0201 in a complex with a human‐derived IgE Fab fragment has been determined. The immunocomplex shows the trivalent binding of Fabs, creating a cross‐linked structure effective in the formation of large complexes on the surface of effector cells. Hydroxylation of proline has implications
Tarja Parkkinen   +4 more
wiley   +1 more source

Biphasic Effects on Allergen‐Specific Type 2 Memory B Cells Over 18 Months Sublingual Immunotherapy for House Dust Mite Allergy

open access: yesAllergy, EarlyView.
Rapid clinical relief of allergy symptoms during 18 months of sublingual immunotherapy (SLIT) for house dust mite (HDM) is associated with increased serum IgE, IgG2, and IgG4 to Der p 1 and Der p 2. Der p 1 and Der p 2 specific Type 2 memory B cells are expanded at 4 months and 12 months of SLIT, with increased expression of CD29 and IgG4.
Lin Hsin   +9 more
wiley   +1 more source

Improvement of Mouse Spermatozoa Freezing at ‐80°C With Ascorbic Acid 2‐Glucoside at Thawing Phase

open access: yesAndrology, EarlyView.
ABSTRACT Background Sperm cryopreservation is the most common method to maintain a great number of mutant mouse lines. However, the use of liquid nitrogen (LN2) for freezing presents considerable problems in terms of cost, safety, and accessibility. For this reason, the storage of semen samples at ‐80° in ultra‐freezers has been increasingly used in ...
Alessia Paradiso   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy