Results 41 to 50 of about 298 (115)

DESIGN AND EVALUATION OF ULTRADEFORMABLE SOFT ELASTIC NANO VESICLE ETHOSOMES FOR DERMAL DELIVERY

open access: yesInternational Journal of Biomedical and Advance Research, 2012
Clotrimazole is an antifungal drug for treatment of cutaneous candidiasis infections. However its oral administration is associated with number of drawbacks. The goal of the current investigation is to evaluate the transdermal potential of novel vesicular carrier, ethosomes, bearing Clotrimazole an antifungal having limited transdermal permeation ...
Ajay Samnani   +4 more
openaire   +2 more sources

A State‐of‐the‐Art Appraisal of Nanomaterials in Microneedles in the Delivery of Therapeutics and Vaccines

open access: yesAdvanced NanoBiomed Research, Volume 5, Issue 3, March 2025.
Nanomaterial‐integrated microneedles revolutionize transdermal delivery, enabling targeted and controlled administration of therapeutics and vaccines. This review explores advancements in design, manufacturing, and applications, emphasizing enhanced drug stability, bioavailability, and patient adherence. Key preclinical and clinical findings as well as
Bwalya Angel Witika   +3 more
wiley   +1 more source

Exploring precision treatments in immune‐mediated inflammatory diseases: Harnessing the infinite potential of nucleic acid delivery

open access: yesExploration, Volume 5, Issue 1, February 2025.
Within this review, an in‐depth exploration of therapeutic nucleic acids and their delivery mechanisms in immune‐mediated inflammatory diseases (IMIDs) is presented. The review encapsulates key elements such as different types of nucleic acid molecules, delivery systems for nucleic acids, and the therapeutic use of nucleic acid delivery for IMIDs ...
Lingxiao Xu   +10 more
wiley   +1 more source

Lipid Horizons: Recent Advances and Future Prospects in LBDDS for Oral Administration of Antihypertensive Agents

open access: yesInternational Journal of Hypertension, Volume 2024, Issue 1, 2024.
The lipid‐based drug delivery system (LBDDS) is a well‐established technique that is anticipated to bring about comprehensive transformations in the pharmaceutical field, impacting the management and administration of drugs, as well as treatment and diagnosis.
Preeti   +10 more
wiley   +1 more source

Formulation and evaluation of transdermal ultradeformable vesicles of aspirin

open access: yesACTA Pharmaceutica Sciencia, 2022
Imran Pasha   +2 more
openaire   +1 more source

SELF-ASSEMBLED ULTRADEFORMABLE PHOSPHOLIPID VESICLES WITH EDGE ACTIVATORS FOR DELIVERY OF TRANSCUTANEOUS BIOACTIVES

open access: yes, 2020
Molecules more than 500 Dalton normally do not permeable through skin. This prevents percutaneous delivery of the large molecular weight therapeutics as well as non-invasive transcutaneous immunization. The flexible or deformable vesicles are called as Transfersome which are derived from two words as ‘Transferred’ from Latin which means ‘To carry ...
openaire   +2 more sources

Ultradeformable lipid vesicles can penetrate the skin and other semi-permeable barriers unfragmented. Evidence from double label CLSM experiments and direct size measurements

open access: yesBiochimica et Biophysica Acta (BBA) - Biomembranes, 2002
The stability of various aggregates in the form of lipid bilayer vesicles was tested by three different methods before and after crossing different semi-permeable barriers. First, polymer membranes with pores significantly smaller than the average aggregate diameter were used as the skin barrier model; dynamic light scattering was employed to monitor ...
Cevc, Gregor   +2 more
openaire   +2 more sources

Development of ultradeformable lipid vesicles comprising polyoxyethylene oleyl ether for targeted drug delivery across the skin

open access: yes, 2008
Transfersome® Vesikel sind ultradeformierbare Wirkstoffträger zur lokalen Behandlung von dermalen Krankheiten in oberflächlichen aber auch tieferen Gewebsschichten. Im Rahmen dieser Arbeit wurde eine universell einsetzbare Transfersome® Formulierung entwickelt, bestehend aus dem Lipiddoppelschicht aufbauenden SPC und weichmachenden Tensid C18:1EO20 ...
openaire   +2 more sources

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