Results 61 to 70 of about 531,876 (306)
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane +7 morewiley +1 more sourceOperation of a free-electron laser from the extreme ultraviolet to the water window [PDF]
, 2007 We report results on the performance of a free-electron laser operating at a wavelength of 13.7 nm where unprecedented peak and average powers for a coherent extreme-ultraviolet radiation source have been measured.T. Jezynski, REDLIN H, T. Hott, Di Pirro, G, Pucyk, P., Simon, C, CIANCHI A, NUNEZ T, E. Sombrowski, Castro, P, M. Körfer, P. Spanknebel, Zagorodnov, I, N. Baboi, SANDNER W, Brovko, O.I, Dardis, J, Poletto, L, D. Proch, Stephan, Frank, Cubaynes, D., Saldin, E. L., Feldhaus, J, Kavanagh, K., KOSTIN D, W. Ackermann, Ch, Gerth, Castellano, M., Khodyachykh, S, Pchalek, N., C. Pagani, SCHMIDT B, A. A. Sorokin, Frisch, J, PLONJES E, Yurkov, M. V., Ivanisenko, Y., KRASSILNIKOV M, Azima, A: Baboi, N, V. Miltchev, L. Petrosyan, I. Will, Oppelt, Anne, T. Edwards, H., K. Pozniak, Shabunov, A.V., Kavanagh, K, Cubaynes, D, Han, J.H., V. Yurkov, M., Shabunov, A., Feldhaus, J., Kostin, D, N, Schnepp, S., Kostin, D., Monaco, Laura, A. Sorokin, A., Roensch, J, Grecki, M., SOROKIN AA, R. Treusch, WEILAND T, M. Kollewe, Koprek, W., Yurkov, M., HAN JH, N. Pchalek, Yeates, Patrick, Schneidmiller, E. A., Tsakov, I, Flottmann, K, L. Saldin, E., HACKER K, Ross, M., Choroba, S., Sandner, W, C. Simon, R. Kammering, Kuhlmann, M., KATALEV V, Schmitz, M, BEUTNER B, Decking, W, Schneidmiller, E.A., SOMBROWSKI E, Saldin, E., I. Brovko, O., Plonjes, E, GRIMM O, CHIADRONI E, TIEDTKE K, Luna, H, G. Petrosyan, Delsim-Hashemi, H., J. Frisch, GERTH C, Grabosch, H, IVANISENKO Y, Limberg, T., Katalev, V, Nuez, T, FAATZ B, DOHLUS M, VOGEL E, K. Flöttmann, Roensch, Juliane, Krassilnikov, Mikhail, Schreiber, S., JALMUZNA W, Rossbach, J, Tischer, M, H. T. Edwards, L. Lilje, WINTER A, LUNA H, A. Bolzmann, LILJE L, Ackermann, W, MOLLER WD, Prat, E., STEPHAN F, SCHMITZ M, A. Delserieys, Stulle, F, K. Wittenburg, Lewis, C. L. S., Seidel, M, WITTENBURG K, M. Sachwitz, Gerth, C, Brovko, O.I., M. Seidel, S. Schnepp, KOCHARYAN V, Jaeschke, E., Staykov, L., Ivanisenko, H.-J. Y., B. Steffen, Katalev, V., DARDIS J, J. Pedregosa Gutierrez, Saldin, E.L., Brandt, A, H. Redlin, Korfer, M, Kennedy, E, J. T. Costello, Kennedy, E.T., SCHMUSER P, KUBE G, SIMON C, Staykov, L, Edwards, H.T., Spanknebel, P., Muller, W, Korepanov, S, Miltchev, V., Pozniak, K, C. L. S. Lewis, F. Stulle, Schreiber, Siegfried, Schmuser, P, Honkavaara, K, Sorokin, A. A., Roehrs, M, Will, Ingo, Vogel, E., Hüning, M., Roehrs, M., Miltchev, Velizar, A: Baboi, D. Kostin, Spesyvtsev, R., Rehlich, K., NICOLOSI, PIERGIORGIO, NAPIERALSKI O, TSAKOV I, PAPARELLA R, A. Azima, Düsterer, S., Petrosyan, B., Schmidt, B., I. Zagorodnov, Winter, A, C.h. Gerth, Pozniak, K., KAVANAGH K, CASTELLANO M, E. Plönjes, J. Roensch, Wellhofer, M, Hahn, U, M. Ross, Poletto, L., Asova, Galina, Luong, M., D. Sertore, Castellano, M, YEATES P, N. Golubeva, Asova, G., FROHLICH L, W. F. O. Müller, Redlin, H, Thom, H., BOLZMANN A, Asova, G, Dohlus, M, Sertore, D, Han, H., Krassilnikov, M., Müller, W.F.O., Saldin, E, Dardis, J., Martins, M, Lewis, Ciaran, Möller, W. D., H. Luna, M. Castellano, Redlin, H., Schneider, J. R., D. Cubaynes, Jaeschke, Eberhard, Yurkov, M.V., Weiland, T., JEZYNSKI T, Romaniuk, R., K. Honkavaara, Richter, M., Delsim-Hashemi, H, Luna, H., A. Eckhardt, FLOTTMANN K, Tiedtke, K, Michelato, P, Khodyachykh, S., Weiland, Thomas, RYBNIKOV V, Lipka, S., BRINKMANN R, Martins, M.,, Golubeva, N., Zagorodnov, I., KOLLEWE M, A. Winter, Görler, M., Ivanisenko, Y, Löhl, F., MARTINS M, Hahn, U., Schmüser, P., Sachwitz, M., Weise, H, Napieralski, O., LUONG M, M. Görler, M. Schmitz, Korepanov, S., KOREPANOV S, Schnepp, Sascha, Pchalek, N, SACHWITZ M, M. Kuhlmann, E. Prat, Sombrowski, E, Richter, M, W. Wurth, CATANI L, V. Rybnikov, THOM H, Oppelt, A., SCHNEPP S, Simon, C., Costello, J. T, Faatz, B., Sorokin, A.A., SPANKNEBEL P, Delsim Hashemi, H, A. Schneidmiller, E., RICHTER M, Bolzmann, A, L. Catani, Sombrowski, E., Paparella, R., LIPKA D, B. Beutner, PAGANI C, Gensch, U., Körfer, M., Nicolosi, P., Yurkov, M, Radcliffe, P, Frisch, Josef, Radcliffe, P., Schlarb, H., Vogel, E, Petersen, B., Kollewe, M., SERTORE D, Rybnikov, V, Balandin, V., Lohl, F, Meyer, M, Napoly, O, KHODYACHYKH S, Proch, D., Shabunov, A, Kennedy, Eugene T., S. Choroba, Ayvazyan, V, Grabosch, H.-J., Nolle, D, Napieralski, O, J. R. Schneider, PRAT E, J. Bähr, W. Sandner, Bahr, J, B. Petersen, A. V. Shabunov, Treusch, R., R. Schneider, J., Edwards, H. T., V. Ayvazyan, Baboi, N., NOLLE D, FRISCH J, H. Han, J., Grimm, O., Ross, Marc, CHOROBA S, M. Krassilnikov, FELDHAUS J, Eckhardt, A., MILTCHEV V, PFLUGER J, Bahr, J., L. Staykov, KORFER M, H. Delsim Hashemi, H. J. Grabosch, CUBAYNES D, KUHLMANN M, O. Napieralski, Han, Jang Hui, M. Meyer, KOPREK W, F. O. Müller, W., U. Hahn, Bähr, Jürgen W., Costello, John T., Shabunov, A. V., ACKERMANN W, LOHL F, POZNIAK K, Frisch, J., Garvey, T., Brovko, O. I., ZAGORODNOV I, Seidel, M., K. Tiedtke, Bolzmann, A., Oppelt, A, SALDIN EL, Balandin, V, Petroysan, L., Decking, W., Edwards, H.T, JAESCHKE E, Treusch, R, T. Kennedy, E., G. Asova, Lewis, C, Lipka, Dirk, Hacker, K, WELLHOFFER M, T. Garvey, CASTRO P, Chiadroni, E., Honkavaara, K., S. Düsterer, HUNING M, ROSS M, Winter, A., CIANCHI, ALESSANDRO, Brandt, A., Pagani, C., Will, I., Roensch, J., DECKING W, ROSSBACH J, Wellhöfer, M., E. Chiadroni, Brinkmann, R, V. Balandin, DELSERIEYS A, Frohlich, L, Kube, G, Schneider, J, Petrosyan, L., ROMANIUK R, Wendt, M, PEDREGOSA GUTIERREZ J, E. L. Saldin, F. Stephan, KENNEDY ET, M. Martins, SHABUNOV AV, J. Pedregosa-Gutierrez, Wittenburg, K, T. Limberg, Grabosch, Hans-Jürgen, Grabosch, H., ECKHARDT A, Wurth, W, Jalmuzna, W, Schmitz, M., Delserieys, A, Steffen, Bernhard, D. Möller, W., Müller, W., Moller, W, Gretchko, V., Schnepp, S, M. Tischer, Zagorodnov, Igor A., Sachwitz, M, Castro, P., PUCYK P, S. Schreiber, Yeates, P, ROENSCH J, Spanknebel, P, Vogel, E. M., NAPOLY O, Cianchi, A, RADCLIFFE P, YURKOV MV, Jezynski, T., Martins, M., Pedregosa-Gutierrez, J, K. Hacker, Chiadroni, E, Edwards, H. T, Michelato, P., U. Gensch, Möller, W., GRECKI M, Rehlich, K, R. Spesyvtsev, Edwards, A., Lewis, S., R. Brinkmann, W. D. Möller, Brinkmann, R., E. T. Kennedy, Dohlus, M., Delserieys, A., W. Decking, Ackermann, Wolfgang, O. Napoly, Wurth, W., P. Nicolosi, Hott, T., AYVAZYAN V, HAHN U, Toleikis, S, Han, J, Kavanagh, Kevin D., Sandner, Wolfgang, M. V. Yurkov, I. Tsakov, D. Nölle, Lilje, L, Catani, L., Weise, H., MULLER WFO, SIMROCK S, ROEHRS M, Monaco, L, Dohlus, Martin, STAYKOV L, M. Hüning, J. H. Han, S. Toleikis, Plönjes, E., Schneidmiller, E, Meyer, M., A. Brandt, V. Shabunov, A., DUSTERER S, Körfer, Markus, Beutner, B., Sandner, W., Garvey, T, Hott, T, OPPELT A, MEYER M, P. Castro, Petrosyan, G., Flöttmann, A., Stephan, F., Wendt, M., Jezynski, W., Grimm, O, Gensch, U, Grecki, M, Kennedy, E. T., Stephan, F, SCHNEIDMILLER EA, Yeates, P., Zapfe, K., Steffen, B, M. Grecki, B. Faatz, COSTELLO JT, A. Oppelt, STULLE F, T. Weiland, Rossbach, J., GORLER M, SEIDEL M, Schmidt, B, SCHREIBER S, LIMBERG T, Brovko, I., Kocharyan, V., Kube, G., PETERSEN B, Azima, SCHLARB H, Schlarb, H, Faatz, B, PROCH D, Ross, M, Lipka, D., Schmüser, Peter, Trines, D., Schreiber, S, HONKAVAARA K, Simrock, S, Romaniuk, R, Khodyachykh, Sergiy, Pflüger, J., Miltchev, V, M. Richter, Rybnikov, V., Costello, J.T, Möller, W.D., Simrock, S., Jaeschke, E, Delserieys, Alice, Petrosyan, Bagrat, Stulle, F., BAHR J, WURTH W, Beutner, B, REHLICH K, GARVEY T, MICHELATO P, W. Jalmuzna, Pagani, Carlo, POLETTO L, Costello, T., K. Rehlich, Spesyvtsev, R, G. Kube, H. Thom, Gerth, Ch., Gensch, Ulrich, Tsakov, I., Schneider, J.R., S. Khodyachykh, E. A. Schneidmiller, Sorokin, A, Paparella, R, Michelato, Paolo, Toleikis, S., H. Weise, Martins, M., Corriea, Klose, K., Prat, E, P. Pucyk, Kammering, R, BALANDIN V, P. Schmüser, Catani, L, Fröhlich, L., TREUSCH R, Luong, M, Ch. Gerth, M. Dohlus, Costello, J.T., HOTT T, TRINES D, Krassilnikov, M, A. Cianchi, E. Jaeschke, Tsakov, Ivan, PETROSYAN L, Klose, K, V. Kocharyan, J. Pflüger, ASOVA G, L. Fröhlich, Edwards, H., K. Zapfe, MONACO L, PETROSYAN B, Napoly, O., Grimm, Oliver, Tischer, M., PETROSYAN G, Ayvazyan, V., SPESYVTSEV R, Koprek, W, K. Klose, Sertore, Daniele, Limberg, T, M. Wellhöfer, M. Roehrs, Staykov, Lazar, BRANDT A, GRABOSCH HJ, Pucyk, P, S. Korepanov, Golubeva, N, Petersen, B, Nölle, D., Lilje, L., WEISE H, Cianchi, A., Monaco, L., Pfluger, J, SCHNEIDER JR, WENDT M, Flöttmann, K., Kuhlmann, M, D. Trines, Ackermann, W., T. Costello, J., Brovko, O. I, O. I. Brovko, KLOSE K, O. Grimm, Eckhardt, A, J. Feldhaus, KAMMERING R, Sertore, D., Will, I, Schneidmiller, A., Proch, D, P. Michelato, GENSCH U, DELSIM HASHEMI H, PCHALEK N, Gorler, M, Jalmuzna, W., H. Schlarb, Tiedtke, K., Rossbach, Jörg, TOLEIKIS S, Y. Ivanisenko, L. S. Lewis, C., Müller, W. F. O., STEFFEN B, Dusterer, S, TISCHER M, R. Romaniuk, ZAPFE K., Flöttmann, Klaus, Wittenburg, K., Weiland, T, Nuñez, T., Nicolosi, P, Azima, A., Petrosyan, B, T. Nuñez, Kammering, R., H.-J. Grabosch, Steffen, B., Lipka, D, Dardis, John, EDWARDS HT, J. Rossbach, B. Schmidt, Kocharyan, V, Costello, J. T., AZIMA A, Kennedy, T., GOLUBEVA N, Huning, M, M. Luong, H. Delsim-Hashemi, DI PIRRO G, Jezynski, T, Sorokin, A., L. Monaco, M. Wendt, Trines, D, Di Pirro, G., Pedregosa-Gutierrez, J., R. Paparella, LEWIS CLS, B. Petrosyan, Schneider, R., L. Poletto, E. Vogel, BABOI N, WILL I, BROVKO OI, K. Kavanagh, F. Löhl, G. Di Pirro, Pedregosa Gutierrez, J, J. Dardis, Kollewe, M, P. Radcliffe, Pagani, C, Choroba, S, Thom, H, P. Yeates, Han, J. H., Petrosyan, G, V. Katalev, Müller, Wolfgang Franz Otto, Petrosyan, L, D. Lipka, Hacker, K., W. Koprek, S. Simrock, Schneider J R, Zapfe, K. (author), PedregosaGutierrez J, Edwards H T, Beutner, B. (author), Lewis C L S, Moller W D, Ayvazyan, V. (author), Asova, G. (author), Schneidmiller E A, Muller W F O, Yurkov M V, Balandin, V. (author), Brandt, A. (author), Gerth Ch, Han J H, Ackermann, W. (author), Costello J T, Azima, A. (author), Zapfe K, Sorokin A A, Saldin E L, DelsimHashemi H, Bähr, J. (author), Bolzmann, A. (author), Baboi, N. (author), Kennedy E T, Nicolosi P, Seidel, M. (author), Shabunov A V +761 morecore +2 more sourcesUpper-Room Ultraviolet Light and Negative Air Ionization to Prevent Tuberculosis Transmission [PDF]
, 2009 Background Institutional tuberculosis (TB) transmission is an important public health problem highlighted by the HIV/AIDS pandemic and the emergence of multidrug- and extensively drug-resistant TB.Ticona, E., Gilman, RH, Navincopa, Marcos, Gilman, R.H., Noakes, Catherine, Carlton A Evans, Patricia Sheen, Gilman Robert H, Gonzalez Armando, Ticona, Eduardo, Gonzalez, A, Mitchell, B., Ramirez, R., Moore, David AJ, Sheen, Patricia, Willi Quino, Mitchell Bailey, Noakes Catherine, Quino Willi, Robert H Gilman, Quino, W, Sheen Patricia, Rocio Ramirez, Armando Gonzalez, Navincopa, M., Sheen, P, Jon S Friedland, A Roderick Escombe, Gilman, Robert H, Martínez Carlos, Martinez, C, Ramirez, Rocio, Escombe, AR, Mitchell, Bailey, Evans, Carlton A, Gonzalez, A., Friedland, Jon S, Navincopa, M, Escombe A. Roderick, Noakes, CJ, Martínez, Carlos, Ramirez, R, Evans, CA, Evans, C.A., Quino, Willi, Bailey Mitchell, Carlos Martínez, Moore, D.A.J., Moore, DAJ, Catherine Noakes, Escombe, A.R., Friedland, J.S., Ticona, E, Moore David A. J, Mitchell, B, Navincopa Marcos, Noakes, C, David A J Moore, Ramirez Rocio, Quinow, W., Friedland Jon S, Noakes, C.J., Sheen, P., Friedland, JS, Martinez, C., Ticona Eduardo, Marcos Navincopa, Evans Carlton A, Gonzalez, Armando, Eduardo Ticona, Escombe, A Roderick +70 morecore +2 more sourcesSPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin +17 morewiley +1 more sourceCONSIDERATIONS CONCERNING THE INFLUENCE OF UV RADIATIONS ON THE BODY [PDF]
Analele Universităţii "Constantin Brâncuşi" din Târgu Jiu: Seria Inginerie, 2019 This paper shows how the association between ultraviolet light (UV) and the diseases produced by the human body. There is strong evidence that exposure to ultraviolet radiation (UVR) is associated with malignancy of basal cell carcinoma, photokeratitis ...Roxana Mecu, Daniela Cîrţînă, Valentin Nănescu +2 moredoaj Spectroscopic observation of planetary and moon exospheres in the ultraviolet
, 2022 The PLanetary extreme Ultraviolet Spectrometer (PLUS) is a project funded by the Italian Space Agency focused on the
development of an extreme (EUV) and far-ultraviolet (FUV) high-performance spectrograph, which adopts a dual
channel optical scheme ...Favaro, Giulio, Milillo, Anna, Faccini, Daniele, Maggioni, Gianluigi, Marta, Padovani, Toso, Giorgio, Andretta, Vincenzo, Uslenghi, Michela C., Corso, Alain Jody, Pelizzo, Maria Guglielmina, Santi, Giovanni, Bazzan, Marco, Fabbrica, Edoardo, Fiorini, Mauro, Carminati, Marco, Fiorini, Carlo E., Incorvaia, Salvatore, Naletto, Giampiero +17 morecore +1 more sourceOptimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity, Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink +3 morewiley +1 more sourceThe hydrogen Lyman α line shape in the exospheres of terrestrial objects in the solar system
Frontiers in Astronomy and Space SciencesThe exospheres of all objects are mostly made of atomic hydrogen. Because the Sun is bright in Lyman α, the properties of the H atoms in the exospheres of certain terrestrial solar system objects can be studied by analyzing the resonantly scattered solar Dolon Bhattacharyya, Edward M. B. Thiemann, Janet Machol, Janet Machol, Gonzalo Cucho-Padin, Gonzalo Cucho-Padin, Sabyasachi Chatterjee, Walter Harris, Edwin Mierkiewicz +8 moredoaj +1 more source