Results 61 to 70 of about 452,874 (311)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

The hydrogen Lyman α line shape in the exospheres of terrestrial objects in the solar system

open access: yesFrontiers in Astronomy and Space Sciences
The exospheres of all objects are mostly made of atomic hydrogen. Because the Sun is bright in Lyman α, the properties of the H atoms in the exospheres of certain terrestrial solar system objects can be studied by analyzing the resonantly scattered solar
Dolon Bhattacharyya   +8 more
doaj   +1 more source

Ultraviolet-visible spectroscopy of Au20 in a) expansion and b) RPMI CCM.

open access: yes, 2019
Ultraviolet-visible spectroscopy of Au20 in a) expansion and b) RPMI CCM.
Katja Bernfur (447519)   +4 more
core   +1 more source

Simultaneous assessment of photosynthetically active and ultraviolet solar radiation [PDF]

open access: yes, 1998
A new dosimetric package for assessing solar radiation affecting photosynthesis in the visible and ultraviolet wavebands in plant canopies has been developed and tested. The package consists of several detectors sensitive to various wavebands between 290
Parisi, A. V.   +5 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Pr3+‐Based Visible‐to‐Ultraviolet Upconversion. A minireview

open access: yesAdvanced Physics Research
Optical upconversion materials doped with lanthanides, such as Yb3+‐Er3+, Yb3+‐Ho3+, and Yb3+‐Tm3+ coped systems, have been intensively studied over the past two decades because they can convert long‐wavelength and low‐energy near‐infrared photons into ...
Leipeng Li   +5 more
doaj   +1 more source

Topical Delivery of Carvedilol Loaded Nano-Transfersomes for Skin Cancer Chemoprevention

open access: yesPharmaceutics, 2020
The β-blocker carvedilol has been shown to prevent skin carcinogenesis in vitro and in vivo. Since systemic absorption of the β-blocker may cause cardiovascular disturbance, we developed a carvedilol loaded transfersome for skin-targeted delivery ...
Mengbing Chen   +9 more
doaj   +1 more source

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