Results 31 to 40 of about 71,333 (243)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Follow the Mass—A Concordance Picture of Tidal Disruption Events

open access: yesThe Astrophysical Journal
Three recent global simulations of tidal disruption events (TDEs) have produced, using different numerical techniques and parameters, very similar pictures of their dynamics.
Julian Krolik, Tsvi Piran, Taeho Ryu
doaj   +1 more source

LEMUR: Large European Module for solar Ultraviolet Research. European contribution to JAXA's Solar-C mission [PDF]

open access: yes, 2011
Understanding the solar outer atmosphere requires concerted, simultaneous solar observations from the visible to the vacuum ultraviolet (VUV) and soft X-rays, at high spatial resolution (between 0.1" and 0.3"), at high temporal resolution (on the order ...
A Bhattacharjee   +73 more
core   +2 more sources

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

Eight Years of Light from ASASSN-15oi: Toward Understanding the Late-time Evolution of TDEs

open access: yesThe Astrophysical Journal
We present results from an extensive follow-up campaign of the tidal disruption event (TDE) ASASSN-15oi spanning δt  ∼ 10–3000 days, offering an unprecedented window into the multiwavelength properties of a TDE during its first ≈8 yr of evolution. ASASSN-
A. Hajela   +28 more
doaj   +1 more source

An Updated Ultraviolet Calibration for the Swift/UVOT

open access: yes, 2011
We present an updated calibration of the Swift/UVOT broadband ultraviolet (uvw1, uvm2, and uvw2) filters. The new calibration accounts for the ~1% per year decline in the UVOT sensitivity observed in all filters, and makes use of additional calibration ...
Breeveld, A. A.   +5 more
core   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Ultrafast Molecular Spectroscopy Using a Hollow-Core Photonic Crystal Fibre Light Source [PDF]

open access: yes, 2018
We demonstrate, for the first time, the application of rare-gas filled hollow-core photonic crystal fibres (HC-PCFs) as tuneable ultraviolet light sources in femtosecond pump-probe spectroscopy.
Belli, Federico   +6 more
core   +2 more sources

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Ultraviolet Quasiperiodic Eruptions from Star–Disk Collisions in Galactic Nuclei

open access: yesThe Astrophysical Journal Letters
“Quasiperiodic eruptions” (QPE) are recurrent nuclear transients with periods of several hours to almost a day, which thus far have been detected exclusively in the X-ray band.
Itai Linial, Brian D. Metzger
doaj   +1 more source

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