Results 51 to 60 of about 3,798 (181)

Solid Olive‐Mill Waste and Biochar Effects on the Bioavailability and Bioactivity of Abscisic Acid in Soil

Journal of Sustainable Agriculture and Environment, Volume 5, Issue 2, June 2026.
Biochar and solid olive‐mill waste differently affected abscisic acid (ABA) bioavailability and bioactivity in soil by altering ABA sorption and soil chemical and microbial properties. The type of amendment and the mechanisms by which it affected ABA bioavailability in soil were key determinants of the final effects on ABA bioactivity. ABSTRACT Natural
María del Valle Muñoz‐Muñoz, Rafael Celis, Rocío López‐Cabeza   +2 more
wiley   +1 more source

Microchip electrophoresis-electrochemical detection platform for analysis of drugs and their metabolites [PDF]

, 2015
U razdoblju ubrzanog rasta farmaceutske industrije razvoj postojećih analitičkih metoda je prespor i ne može zadovoljiti potrebe zahtjevnih metaboličkih analiza novih lijekova i novih kemijskih entiteta (kemikalija iz okoliša i kućanstva).
Lenić, Ines
core   +1 more source

Pastinaca sativa L.: Nutritional Composition, Phytochemistry, and Pharmacological Properties Supporting Its Potential as a Functional Food and Therapeutic Agent

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Food‐grade processing of Pastinaca sativa (parsnip) converts a nutrient‐rich plant matrix (dietary fiber, fructans, phenolics) through washing/slicing/enzymatic treatment and ingredient preparation into functional food ingredients, including fiber concentrates, antioxidant‐rich fractions, and parsnip powders/extracts.
Somanjana Khatua, Anish Nag, Surajit Sen, Jit Sarkar, Krishnendu Acharya, Daniela Calina, William N. Setzer, Javad Sharifi‐Rad   +7 more
wiley   +1 more source

Ruthenium Complexes in Protein Science: Heading a New Generation of Therapeutic and Analytical Tools

Angewandte Chemie, Volume 138, Issue 4, 22 January 2026.
This review presents the latest advances in the development of ruthenium complexes within the field of protein science, highlighting their potential applications in biomedical and bioanalytical fields. Abstract Ruthenium complexes are distinguished by their versatile coordination chemistry, redox behaviors and photochemical properties. In recent years,
Liyan Zhang, Yun Chen, Sylvestre Bonnet
wiley   +2 more sources

Umbelliferone and scopoletin target tyrosine kinases on fibroblast-like synoviocytes to block NF-κB signaling to combat rheumatoid arthritis

Frontiers in Pharmacology, 2022
Rheumatoid arthritis (RA) is a complex autoimmune condition primarily affecting synovial joints, which targeted synthetic drugs have damaging safety issues.
Qilei Chen, Wenmin Zhou, Yueming Huang, Yuanyang Tian, Sum Yi Wong, Wing Ki Lam, Ka Yee Ying, Jianye Zhang, Hubiao Chen   +8 more
doaj   +1 more source

Citrus phenylpropanoids and defence against pathogens. Part I: Metabolic profiling in elicited fruits [PDF]

, 2016
Penicillium spp. are among the major postharvest pathogens of citrus fruit. Induction of natural resistance in fruits constitutes one of the alternatives to chemical fungicides.
Ballester Frutos, Ana Rosa, Bovy, A.G., De Vos, R.C.H., González-Candelas, Luis, Lafuente, María Teresa   +4 more
core   +1 more source

Emerging Role of Ferroptosis in Diabetes and Associated Complications: When Metabolic Dysregulation Meets Cell Death

Cell Proliferation, Volume 59, Issue 5, May 2026.
This study identifies ferroptosis as a key driver of diabetes and its complications via iron metabolism and lipid peroxidation, elucidates organelle interactions underlying cell vulnerability, and provides insights for targeted therapies against metabolic disorders.
Zheng Wang, Ying Zhang, Yue Xu, Mengyuan Yang, Yuan Wei, Yuan Li, Tongyue Yang, Xu Wang, Chaona Yang, Qi Feng, Guolan Xing   +10 more
wiley   +1 more source

Design and Characterization of PLA Bilayer Films Containing Lignin and Cellulose Nanostructures in Combination With Umbelliferone as Active Ingredient

Frontiers in Chemistry, 2019
Poly (lactic acid) (PLA) bilayer films, containing cellulose nanocrystals (CNC) or lignin nanoparticles (LNP) and Umbelliferone (UMB) were extruded and successfully layered by thermo-compression starting from monolayer films.
Magdalena L. Iglesias Montes, Francesca Luzi, Franco Dominici, Luigi Torre, Viviana P. Cyras, Liliana B. Manfredi, Debora Puglia   +6 more
doaj   +1 more source

ACSL1‐Dependent Microglial Lipoimmunometabolic Reprogramming Underlies Cognitive Deficits in Alcohol Use Disorder

Advanced Science, Volume 13, Issue 21, 13 April 2026.
This study reveals that chronic alcohol exposure selectively upregulates ACSL1 expression in prefrontal cortical microglia, driving lipid metabolism reprogramming and lipid droplet accumulation, which activates the NLRP3 inflammasome and sustains neuroinflammation. To reverse this process, a dual‐targeted lipid nanoparticle, siACSL1@LNP‐MR, is designed
Liang Hao, Xing‐Rui Cao, Bai‐Qiang Li, Fu‐Ying Zhao, Jia‐Mei Wang, Rui‐Kang Gao, Zhi‐Peng Cao, Zhen‐Xian Du, Hua‐Qin Wang   +8 more
wiley   +1 more source

7-Acetoxycoumarin Inhibits LPS-Induced Inflammatory Cytokine Synthesis by IκBα Degradation and MAPK Activation in Macrophage Cells

Molecules, 2020
Acetylation involves the chemical introduction of an acetyl group in place of an active hydrogen group into a compound. In this study, we synthesized 7-acetoxycoumarin (7AC) from acetylation of umbelliferone (UMB).
Taejin Park, Jin-Soo Park, Ji Han Sim, Seung-Young Kim   +3 more
doaj   +1 more source