Results 71 to 80 of about 3,798 (181)

Activity of neutral and alkaline ceramidases on fluorogenic N-acylated coumarin-containing aminodiols

Journal of Lipid Research, 2015
Ceramidases catalyze the cleavage of ceramides into sphingosine and fatty acids. Previously, we reported on the use of the RBM14 fluorogenic ceramide analogs to determine acidic ceramidase activity.
Mireia Casasampere, Luz Camacho, Francesca Cingolani, Josefina Casas, Meritxell Egido-Gabás, José Luís Abad, Carmen Bedia, Ruijuan Xu, Kai Wang, Daniel Canals, Yusuf A. Hannun, Cungui Mao, Gemma Fabrias   +12 more
doaj   +1 more source

Bioactive Phytochemical Compounds in Medicago sativa L. (Alfalfa): A Systematic Review of Biological Properties and Therapeutic Relevance in Nutraceutical and Functional Food Implications

Food Frontiers, Volume 7, Issue 2, March 2026.
ABSTRACT Medicago sativa L. (alfalfa) harbors a remarkably diverse reservoir of bioactive secondary metabolites. Flavonoids, isoflavones, and triterpenoid saponins dominate its bioactivity landscape, driving potent antioxidant, anti‐inflammatory, antimicrobial, estrogenic, hypolipidemic, and cytotoxic actions through redox modulation, membrane ...
Parham Joolaei Ahranjani, Hamid Rashidi Nodeh, Zahra Esfandiari, Giovanna Ferrentino   +3 more
wiley   +1 more source

MICROWAVE-ASSISTED SYNTHESIS AND PKA DETERMINATION OF UMBELLIFERONE: AN EXPERIMENT FOR THE UNDERGRADUATE ORGANIC CHEMISTRY LABORATORY

Química Nova
A synthetic procedure for obtaining the fluorescent coumarin umbelliferone (7-hydroxycoumarin) and its spectral parameters were fully developed aiming at an undergraduate organic chemistry laboratory class.
Thiago M. Pereira, Daiana F. P. Franco, Felipe Vitório, Ronaldo C. Amaral, Aparecida C. Ponzoni, Arthur E. Kümmerle   +5 more
doaj   +1 more source

Isolation of Endogenous Activator of Glucuronide For­mation in Liver [PDF]

, 1962
A purified compound of the activator of glucuronide formation was isolated from a boiled extract of rat liver by charcoal adsorption, ethanol fractionation of barium salts, and finally paper and Dowex-l column chromatographies.
Taketa, Kazuhisa
core   +1 more source

Mycochemical Diversity and Therapeutic Potential of Hymenochaetoid Fungi from Central Asia: Regional and Global Perspectives

New Zealand Journal of Botany, Volume 64, Issue 1, March 2026.
Central Asia harbors a rich yet understudied assemblage of wood‐inhabiting Hymenochaetoid fungi. This review delivers the first comprehensive synthesis of 43 poroid species representing 18 genera documented across montane forests, steppes, and xeric habitats.
Yusufjon Gafforov, Milena Rašeta, Sylvie Rapior, Manzura Yarasheva, Oksana Mykchaylova, Rustamjon Allaberdiev, Şule İnci, Dilfuza Berdieva, Arshad Mehmood Abbasi, Shikhnazar Khodjaev, Dian‐Ming Hu, Weijun Yang, Abudujilili Abuduaini, Maria Letizia Taddei, Mengcen Wang, Islomjon Urinboev, Jiajia Chen   +16 more
wiley   +1 more source

Chemical Constituents and Antidiabetic Activity of Dichloromethane Extract from Ficus carica Leaves

Diabetes, Metabolic Syndrome and Obesity, 2023
Limei Lin, Yin Zhang Department of Pharmacy, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, People’s Republic of ChinaCorrespondence: Yin Zhang, Department of Pharmacy, The Second Affiliated Hospital of Fujian Medical ...
Lin L, Zhang Y
doaj  

Introducing the Cis‐2,3‐Bis(trifluoromethyl)cyclopropyl Chemotype: Late‐Stage Installation and Stereoelectronic Properties

ChemistryEurope, Volume 4, Issue 2, February 2026.
The cis‐2,3‐bis(trifluoromethyl)cyclopropyl chemotype is introduced. The steric demand of this motif is intermediate between that of the heptafluoroisopropyl and prefluorotertbutyl groups; yet, it induces significantly less lipophilicity than these due to its facial polarity.
Daniel Gaviña, Zeyu Feng, David Herrero, Martin Simon, Christopher Golz, Manuel Alcarazo   +5 more
wiley   +1 more source

Antifungal activity of davanone-type sesquiterpenes from Artemisia lobelii var. conescens [PDF]

Journal of the Serbian Chemical Society, 2004
Five tetrahydrofuran sesquiterpenes, so-called davanones, and coumarin umbelliferone isolated from Artemisia lobelii All. var. canescens (DC.) Briqu, were tested for antifungal activity. All the compounds inhibited the growth of the applied fungi.
VELE TESEVIC, SLOBODAN MILOSAVLJEVIC, MARINA SOKOVIC, PEDJA JANACKOVIC, SNEZANA TRIFUNOVIC, VLATKA VAJS   +5 more
doaj  

Umbelliferone Impedes Biofilm Formation and Virulence of Methicillin-Resistant Staphylococcus epidermidis via Impairment of Initial Attachment and Intercellular Adhesion

Frontiers in Cellular and Infection Microbiology, 2019
Staphylococcus epidermidis is an opportunistic human pathogen, which is involved in numerous nosocomial and implant associated infections. Biofilm formation is one of the prime virulence factors of S.
Thirukannamangai Krishnan Swetha, Murugesan Pooranachithra, Ganapathy Ashwinkumar Subramenium, Velayutham Divya, Krishnaswamy Balamurugan, Shunmugiah Karutha Pandian   +5 more
doaj   +1 more source

Umbelliferone and eriodictyol suppress the cellular entry of SARS-CoV-2

Cell & Bioscience, 2023
Background Artemisia argyi (A. argyi), also called Chinese mugwort, has been widely used to control pandemic diseases for thousands of years since ancient China due to its anti-microbial infection, anti-allergy, and anti-inflammation activities ...
Fang-Ju Cheng, Chien-Yi Ho, Tzong-Shiun Li, Yeh Chen, Yi-Lun Yeh, Ya-Ling Wei, Thanh Kieu Huynh, Bo-Rong Chen, Hung-Yu Ko, Chen-Si Hsueh, Ming Tan, Yang-Chang Wu, Hui-Chi Huang, Chih-Hsin Tang, Chia-Hung Chen, Chih-Yen Tu, Wei-Chien Huang   +16 more
doaj   +1 more source