Results 71 to 80 of about 1,187 (117)
Cell Proliferation, Volume 59, Issue 5, May 2026.This study identifies ferroptosis as a key driver of diabetes and its complications via iron metabolism and lipid peroxidation, elucidates organelle interactions underlying cell vulnerability, and provides insights for targeted therapies against metabolic disorders.
Zheng Wang +10 more
wiley +1 more source
ISOLATION OF SCOPOLETIN, SKIMMIN AND UMBELLIFERONE FROM THE TRUNK-BARK OF SKIMMIA LAUREOLA HOOK
, 1960 Scopoletin.
D. K. MULLICK, S. R. BHATTACHARJEE
core +1 more source
2-Oxo-2H-chromen-7-yl 3-methylbutanoate
IUCrDataThe title compound, C14H14O4, was synthesized by O-acylation of umbelliferone with isovaleryl chloride in the presence of diethyl ether as a solvent and pyridine as a base. The side chain moiety i.e.
Akoun Abou +4 more
doaj +1 more source
Acta Societatis Botanicorum Poloniae, 2014 The ultrastructure and morphology of roots treated with coumarin and umbelliferone as well as the reversibility of the coumarins effects caused by exogenous GA, were studied in Arabidopsis thaliana.
Ewa Kupidłowska
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Advanced Science, Volume 13, Issue 21, 13 April 2026.This study reveals that chronic alcohol exposure selectively upregulates ACSL1 expression in prefrontal cortical microglia, driving lipid metabolism reprogramming and lipid droplet accumulation, which activates the NLRP3 inflammasome and sustains neuroinflammation. To reverse this process, a dual‐targeted lipid nanoparticle, siACSL1@LNP‐MR, is designed
Liang Hao +8 more
wiley +1 more source
SYNTHESIS AND EVALUATION OF SOME UMBELLIFERONE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS
, 2018 Seventeen 7-hydroxy coumarin (umbelliferone) derivatives were synthesized in an almost quantitative yield via reaction with the corresponding ethylchloroacetate, p-substituted benzyl chloride, 2-bromoacetophenone or 2-chloroacetanilide in the presence of
Menshawy A. Mohamed*, Adnan A. Beckeit, Adel S. El-Azab, Ghada F. Mohamed, Sami G. Abdel-Hamid, and Maged S. Abdel-Kader
core +1 more source
Chemical Constituents and Antidiabetic Activity of Dichloromethane Extract from Ficus carica Leaves
Diabetes, Metabolic Syndrome and Obesity, 2023 Limei Lin, Yin Zhang Department of Pharmacy, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, People’s Republic of ChinaCorrespondence: Yin Zhang, Department of Pharmacy, The Second Affiliated Hospital of Fujian Medical ...
Lin L, Zhang Y
doaj
Context‐Dependent Chemoselectivity of Aromatic C‐Methyltransferases
ChemBioChem, Volume 27, Issue 8, April 2026.Chemoselectivity is context‐dependent: The SAM‐dependent C‐MTs SfmM2 and NapB5 from streptomycetes catalyze the C‐ and/or O‐dimethylation of aromatic substrates, including l‐tyrosine and flavonoids. C‐methylation activity requires precise substrate recognition and positioning to ensure proximity between the target carbon nucleophile and the methyl ...
Juliane Breiltgens +4 more
wiley +1 more source
Antifungal activity of davanone-type sesquiterpenes from Artemisia lobelii var. conescens [PDF]
Journal of the Serbian Chemical Society, 2004 Five tetrahydrofuran sesquiterpenes, so-called davanones, and coumarin umbelliferone isolated from Artemisia lobelii All. var. canescens (DC.) Briqu, were tested for antifungal activity. All the compounds inhibited the growth of the applied fungi.
VELE TESEVIC +5 more
doaj
New fluorogenic probes for neutral and alkaline ceramidases
Journal of Lipid Research, 2019 New fluorogenic ceramidase substrates derived from the N-acyl modification of our previously reported probes (RBM14) are reported. While none of the new probes were superior to the known RBM14C12 as acid ceramidase substrates, the corresponding nervonic ...
Mireia Casasampere +9 more
doaj +1 more source