Results 61 to 70 of about 4,051 (210)
International Journal of Food Properties, 2021 In this study, the banana flower was divided into bract and male flowers and extracted with water and ethanol, at different temperatures, and then the functionality of the obtained extract was evaluated and the bioactive compounds were analyzed.
Shu-Hua Chiang +3 more
doaj +1 more source
Advanced Science, Volume 13, Issue 21, 13 April 2026.This study reveals that chronic alcohol exposure selectively upregulates ACSL1 expression in prefrontal cortical microglia, driving lipid metabolism reprogramming and lipid droplet accumulation, which activates the NLRP3 inflammasome and sustains neuroinflammation. To reverse this process, a dual‐targeted lipid nanoparticle, siACSL1@LNP‐MR, is designed
Liang Hao +8 more
wiley +1 more source
Context‐Dependent Chemoselectivity of Aromatic C‐Methyltransferases
ChemBioChem, Volume 27, Issue 8, April 2026.Chemoselectivity is context‐dependent: The SAM‐dependent C‐MTs SfmM2 and NapB5 from streptomycetes catalyze the C‐ and/or O‐dimethylation of aromatic substrates, including l‐tyrosine and flavonoids. C‐methylation activity requires precise substrate recognition and positioning to ensure proximity between the target carbon nucleophile and the methyl ...
Juliane Breiltgens +4 more
wiley +1 more source
Umbelliferone and Esculetin: Inhibitors or Substrates for Polyphenol Oxidases?
Biological and Pharmaceutical Bulletin, 2008 Recently, an interesting debate arose about the nature (substrate versus inhibitor) of esculetin, a coumarin derivative, for mushroom polyphenol oxidase (PPO). The present study examined the behavior of PPOs preparations from fungal and plant origin towards esculetin as a substrate. Both enzymes were able to oxidize esculetin though at a slow rate.
Sollai, F +4 more
openaire +3 more sources
, 2018 In this paper we established the effect on the extent of the geranylation step of selected O-prenyl phenylpropanoids by their biosynthetic precursors (e.g. ferulic acid and umbelliferone) in cultured calli from Anethum graveolens L.
Salvatore Genovesea +7 more
core +2 more sources
Phasentrennung von Nukleinsäuren: Mechanismen, Eigenschaften und Anwendungen
Angewandte Chemie, Volume 138, Issue 11, 9 March 2026.Jüngste Entdeckungen zeigen, dass einzelsträngige langkettige Nukleinsäuren temperaturinduziert phasentrennen und dabei mikrometergroße Kondensate bilden. Dieser Minireview fasst das aktuelle mechanistische Verständnis dieses Phänomens zusammen, beschreibt Strategien zur gezielten Kontrolle der physikalischen und chemischen Eigenschaften der Kondensate
Weixiang Chen +2 more
wiley +1 more source
Journal of Lipid Research, 2015 Ceramidases catalyze the cleavage of ceramides into sphingosine and fatty acids. Previously, we reported on the use of the RBM14 fluorogenic ceramide analogs to determine acidic ceramidase activity.
Mireia Casasampere +12 more
doaj +1 more source
Phase Separation of Nucleic Acids: Mechanisms, Properties, and Applications
Angewandte Chemie International Edition, Volume 65, Issue 11, 9 March 2026.Recent discoveries have shown that single‐stranded long‐chain nucleic acids can undergo temperature‐induced phase separation, enabling formation of micrometer‐sized condensates. This Minireview discusses the current mechanistic understanding of this phenomenon, highlights strategies for controlling the physical and chemical properties of these ...
Weixiang Chen +2 more
wiley +1 more source
Food Frontiers, Volume 7, Issue 2, March 2026.ABSTRACT Medicago sativa L. (alfalfa) harbors a remarkably diverse reservoir of bioactive secondary metabolites. Flavonoids, isoflavones, and triterpenoid saponins dominate its bioactivity landscape, driving potent antioxidant, anti‐inflammatory, antimicrobial, estrogenic, hypolipidemic, and cytotoxic actions through redox modulation, membrane ...
Parham Joolaei Ahranjani +3 more
wiley +1 more source
Chemical Constituents and Antidiabetic Activity of Dichloromethane Extract from Ficus carica Leaves
Diabetes, Metabolic Syndrome and Obesity, 2023 Limei Lin, Yin Zhang Department of Pharmacy, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, People’s Republic of ChinaCorrespondence: Yin Zhang, Department of Pharmacy, The Second Affiliated Hospital of Fujian Medical ...
Lin L, Zhang Y
doaj