Results 81 to 90 of about 1,187 (117)

Additional file 3 of Umbelliferone and eriodictyol suppress the cellular entry of SARS-CoV-2

, 2023
Additional file 3: Fig. S3 Umbelliferone represses the wild-type SARS-CoV-2-associated pulmonary inflammation in vivo.The mice infected with VSVG or wild-type SARS-CoV-2 pseudoviruses were sacrificed after oral administration with sterilized water, 70 mg/
Chia-Hung Chen (504554), Fang-Ju Cheng (11040858), Bo-Rong Chen (2352361), Wei-Chien Huang (16464271), Tzong-Shiun Li (16464256), Chih-Yen Tu (162922), Yeh Chen (680848), Ya-Ling Wei (216239), Ming Tan (34506), Yi-Lun Yeh (16464259), Thanh Kieu Huynh (16464262), Yang-Chang Wu (4607), Hui-Chi Huang (180405), Chien-Yi Ho (16464253), Chih-Hsin Tang (104506), Hung-Yu Ko (16464265), Chen-Si Hsueh (16464268)   +16 more
core  

Umbelliferone Inhibits Spermatogenic Defects and Testicular Injury in Lead-Intoxicated Rats by Suppressing Oxidative Stress and Inflammation, and Improving Nrf2/HO-1 Signaling

Drug Design, Development and Therapy, 2020
Mohammed F Alotaibi,1 Fakhria Al-Joufi,2 Howida S Abou Seif,3 Mohammed A Alzoghaibi,1 Laiche Djouhri,4 Ahmad F Ahmeda,5 Ayman M Mahmoud6 1Physiology Department, College of Medicine, King Saud University, Riyadh 11461, Saudi Arabia; 2Department of ...
Alotaibi MF, Al-Joufi F, Abou Seif HS, Alzoghaibi MA, Djouhri L, Ahmeda AF, Mahmoud AM   +6 more
doaj  

Coumarin Compounds in Callus Cultures

Natural Product Communications, 2014
Coronilla scorpioides (L.) W.D.J. Koch is known for producing several compounds with pharmaceutical interest, such as the hydroxycoumarins umbelliferone, scopoletin and daphnoretin, the dihydrofuranocoumarin marmesin, and the furocoumarin psoralen.
Anna Piovan, Raffaella Filippini, Gabbriella Innocenti   +2 more
doaj   +1 more source

Effect of umbelliferone on adjuvant-induced arthritis in rats by MAPK/NF-κB pathway

, 2019
Liu Ouyang, Yang Dan, Zengwu Shao, Shuhua Yang, Cao Yang, Guohui Liu, Wu Zhou, Deyu Duan Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, People’s Republic of China ...
Dan Y, Shao Z, Ouyang L, Zhou W, Duan D, Yang S, Yang C, Liu G   +7 more
core  

Fabrication, optimization, and characterization of umbelliferone β-D-galactopyranoside-loaded PLGA nanoparticles in treatment of hepatocellular carcinoma: in vitro and in vivo studies

, 2017
Vikas Kumar,1 Prakash Chandra Bhatt,2 Mahfoozur Rahman,1 Gaurav Kaithwas,3 Hani Choudhry,4,5 Fahad A Al-Abbasi,4 Firoz Anwar,4 Amita Verma6 1Natural Product Drug Discovery Laboratory, Department of Pharmaceutical Sciences, Faculty of Health Sciences ...
Kumar V, Verma A, Al-Abbasi FA, Anwar F, Kaithwas G, Bhatt PC, Choudhry H, Rahman M   +7 more
core  

Effect of quercetin and umbelliferone on the transcript level of Penicillium expansum genes involved in patulin biosynthesis

, 2009
Penicillium expansum is commonly associated with patulin accumulation in pome fruits. In in vitro studies, two phenolic compounds (quercetin and umbelliferone) proved to be effective in reducing patulin accumulation, particularly when applied in ...
Sanzani SM, Schena L, NIGRO, Franco, IPPOLITO, Antonio, De Girolamo A   +4 more
core   +1 more source

Exposure to Umbelliferone Reduces Ralstonia solanacearum Biofilm Formation, Transcription of Type III Secretion System Regulators and Effectors and Virulence on Tobacco

Frontiers in Microbiology, 2017
Ralstonia solanacearum is one of the most devastating phytopathogens and causes bacterial wilt, which leads to severe economic loss due to its worldwide distribution and broad host range.
Liang Yang, Shili Li, Xiyun Qin, Gaofei Jiang, Gaofei Jiang, Juanni Chen, Bide Li, Xiaoyuan Yao, Peibo Liang, Yong Zhang, Wei Ding   +10 more
doaj   +1 more source

A simple umbelliferone based fluorescent probe for the detection of nitroreductase [PDF]

, 2018
A simple nitrobenzyl-umbelliferone (NCOU1) was synthesised containing a nitroreductase (NTR) trigger moiety. The presence of NTR, resulted in the fragmentation of the parent molecule and release of the highly emissive fluorophore umbelliferone via an NTR-
Elmes, Robert B.P., Tony D. James, Alex Hayden, Adam C. Sedgwick, Hayden, Alex, Robert B. P. Elmes, Bull, Steven D., Hill, Barry, Steven D. Bull, Sedgwick, Adam C., James, Tony D., Barry Hill   +11 more
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MICROWAVE-ASSISTED SYNTHESIS AND PKA DETERMINATION OF UMBELLIFERONE: AN EXPERIMENT FOR THE UNDERGRADUATE ORGANIC CHEMISTRY LABORATORY

, 2018
A synthetic procedure for obtaining the fluorescent coumarin umbelliferone (7-hydroxycoumarin) and its spectral parameters were fully developed aiming at an undergraduate organic chemistry laboratory class.
Daiana F. P. Franco (6045857), Thiago M. Pereira (4491985), Felipe Vitório (6045860), Aparecida C. Ponzoni (6045863), Arthur E. Kümmerle (5342693), Ronaldo C. Amaral (5502296)   +5 more
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Coumarin Compounds with 6- or 7-(4-Aminobutynyloxy) Substituent: Synthesis, In Vitro Cytotoxicity and In Silico DNA Binding Studies

Molecules
Coumarin compounds are of great interest in drug development research. Various substituents on the coumarin core significantly influence its biological activity.
Anarkul S. Kishkentayeva, Mohammad S. Hamad, Victor A. Savelyev, Zhasmin A. Boyaubayeva, Andrey I. Khlebnikov, Andrey G. Pokrovsky, Yurii V. Gatilov, Almagul S. Makhmutova, Elvira E. Shults   +8 more
doaj   +1 more source