Results 71 to 80 of about 204,149 (306)

ANGPTL8 deficiency attenuates lipopolysaccharide-induced liver injury by improving lipid metabolic dysregulation

Journal of Lipid Research
Liver injury is closely related to poor outcomes in sepsis patients. Current studies indicate that sepsis is accompanied by metabolic disorders, especially those related to lipid metabolism.
Ying Feng, Shan Luo, Chen Fang, Shinan Ma, Dandan Fan, Yanghui Chen, Zhuo Chen, Xiang Zheng, Yijun Tang, Xiaobei Duan, Xingling Liu, Xuzhi Ruan, Xingrong Guo   +12 more
doaj   +1 more source

Effects of marginal umbilical cord insertion on the prognosis of fetus

Clinical and Experimental Obstetrics & Gynecology, 2020
Objective: To investigate the effect of marginal placental insertion of the umbilical cord on the prognosis of a fetus. Material and Methods: Retrospective analysis was performed to compare the differences in fetal weight (FW), placental weight (PW ...
Y. Tian, H. Luo, M. He
doaj   +1 more source

Beyond Extracellular Vesicle (EV) Hype: Practical Solutions and Remaining Hurdles in EV Research, Manufacturing, and Clinical Translation

Advanced Science, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale mediators of intercellular communication with diverse molecular cargoes that reflect their cell of origin. Advances in isolation, detection, and single‐particle analytics have revealed increasing molecular and functional heterogeneity, while exposing limitations in how EV identity and activity are ...
David J. Lundy, Zoe L. Chau, Sheng‐You Chen, Nanami Fujisawa, John J. Hill, Barnett M. Hsu, Joanne K. Liu, Karol W. Mai, James J. Lai   +8 more
wiley   +1 more source

Combined multiplex polymerase chain reaction-based targeted next−generation sequencing and serum 1, 3-β-D-glucan for differential diagnosis of Pneumocystis pneumonia and Pneumocystis colonization

Frontiers in Cellular and Infection Microbiology
Background and ObjectivePneumocystis jirovecii pneumonia (PjP) remains an important cause of morbimortality worldwide, and differentiating Pneumocystis jirovecii (P. jirovecii) infection from P.
Hansheng Wang, Xiao Chen, Xiaofeng Wu, Qizhen Cao, Yi Wu, Fang Wang, Yunyun Wang, Yanhui Zhou, Yijun Tang, Tao Ren, Meifang Wang   +10 more
doaj   +1 more source

Prenatal Diagnosis of Umbilical Cord Ulcer: A Report of Two Cases

Case Reports in Obstetrics and Gynecology, 2019
Umbilical cord ulcer is related to fetal intestinal atresia or meconium; perforation of the ulcer causes fetal deterioration leading to fetal and neonatal death owing to fetal hemorrhage.
Daisuke Katsura, Suzuko Moritani, Shunichiro Tsuji, Kaori Hayashi, Kazutaka Yamada, Shinsuke Tokoro, Kounosuke Suzuki, Fuminori Kimura, Takashi Murakami   +8 more
doaj   +1 more source

Immunomodulatory effects of human umbilical cord wharton's Jelly-Derived mesenchymal stem cells on differentiation, maturation and endocytosis of monocyte-derived dendritic cells [PDF]

, 2013
The Wharton's jelly of the umbilical cord is believed to be a source of mesenchymal stem cells (MSCs) which can be therapeutically applied in degenerative diseases.
Bonab, M.M., Hadjati, J., Latifpour, M., Masoud, A., Nicknam, M.H., Nikbin, B., Saeidi, M., Shakiba, Y.   +7 more
core  

Whole transcriptome analysis of human erythropoietic cells during ontogenesis suggests a role of VEGFA gene as modulator of fetal hemoglobin and pharmacogenomic biomarker of treatment response to hydroxyurea in β-type hemoglobinopathy patients [PDF]

, 2017
Background: Human erythropoiesis is characterized by distinct gene expression profiles at various developmental stages. Previous studies suggest that fetal-to-adult hemoglobin switch is regulated by a complex mechanism, in which many key players still ...
Ali, Bassam R., Chondrou, Vasiliki, John, Anne, Kastrinou, Vlasia, Katsila, Theodora, Kolovos, Petros, Kourakli, Alexandra, Papachatzopoulou, Adamantia, Patrinos, George P., Pavlidaki, Alexia, Sgourou, Argyro, Symeonidis, Argiris   +11 more
core   +5 more sources

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Association of dietary patterns with all-cause and cardiovascular disease mortality in cardiovascular-kidney-metabolic syndrome: a cohort study

Nutrition Journal
Background Cardiovascular-kidney-metabolic (CKM) syndrome, defined by the coexistence of cardiovascular disease (CVD), chronic kidney disease, and metabolic disorders, significantly increases mortality risk.
Ya Shao, Yu Wang, Desheng Luo, Xu Zhou, Maoqian Chen, Longti Li, Huiqin Zhong   +6 more
doaj   +1 more source

Concise review on clinical applications of conditioned medium derived from human umbilical cord-mesenchymal stem cells (UC-MSCS) [PDF]

, 2018
In recent years, mesenchymal stem cells have provoked much attentiveness in the field of regenerative medicine because of their differentiation potential and the capability to facilitate tissue repair via the emancipation of biologically active molecules.
Banerjee, Antara, Di Liddo, Rosa, Gopinath, Madhumala, Jothimani, Ganesan, Marotta, Francesco, Murugesan, Ramachandran, Pathak, Surajit, Sriramulu, Sushmitha   +7 more
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