Results 61 to 70 of about 303,748 (255)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

Chiral Nanoparticles Suppress Inflammatory Infiltration to Promote Extracellular Matrix Remodeling for Ectopia Lentis Therapy

open access: yesAdvanced Science, EarlyView.
L‐cysteine‐configured chiral polyurethane nanoparticles suppress ocular inflammation and reduce extracellular matrix (ECM) degradation in ectopia lentis by regulating macrophages polarization and inhibiting nuclear factor kappa B signaling pathway. By promoting zonular fiber‐associated protein restoration and tissue repair, this minimally invasive ...
Yinuo Wen   +17 more
wiley   +1 more source

U-shaped association of the stress hyperglycemia ratio with all-cause mortality and premature death in patients with cardiovascular disease: a cohort study

open access: yesDiabetology & Metabolic Syndrome
Background The stress hyperglycemia ratio (SHR) is recognized as a significant indicator of relative hyperglycemia that has demonstrated to correlate with poor outcomes, including elevated mortality rates in individuals facing severe acute conditions ...
Na Wang   +6 more
doaj   +1 more source

TET1 inhibits the migration and invasion of cervical cancer cells by regulating autophagy

open access: yesEpigenetics
Methylation modifications play pertinent roles in regulating gene expression and various biological processes. The silencing of the demethylase enzyme TET1 can affect the expressions of key oncogenes or tumour suppressor genes, thus contributing to ...
Ji Ren   +6 more
doaj   +1 more source

GIANT UMBILICAL-CORD ASSOCIATED WITH CORD HEMANGIOMA

open access: yes, 1993
A 6-h-old girl was transferred to the Pediatric Surgery Department of Sisli Children's Hospital due to a giant umbilical cord. Radiologic and laboratory studies were within normal limits.
BULUT, M   +5 more
core   +1 more source

Matrix Stiffness Induces Endothelial Network Senescence

open access: yesAdvanced Science, EarlyView.
Using a 3D human in vitro model that decouples mechanical stress from inflammatory or biochemical signals, matrix stiffening induces a senescence phenotype in endothelial networks. This mechano‐induced senescence activates Notch signaling, and pharmacologic Notch inhibition attenuates this stiffness‐induced senescence.
Jiyeon Song   +6 more
wiley   +1 more source

Relationship between newborn Acid-Base status and umbilical cord morphology [PDF]

open access: yesActa Medica Iranica, 2001
ess the relationship between umbilical cord blood gases at birth and morphology of umbilical cord, in a prospective study of 200 consecutive term delivery, we investigated the relationship between umbilical cord morphology characteristics (umbilical crd ...
Marssosi V, Masoomi F
doaj   +2 more sources

A Forsythiaside A-loaded, oxygen-releasing thermosensitive hydrogel accelerates diabetic wound healing by remodeling the microenvironment

open access: yesMaterials & Design
The healing of diabetic wounds is severely compromised by an adverse microenvironment characterized by persistent hypoxia, infection, and inflammation, necessitating the development of innovative and integrated therapeutic strategies.
Wenbo Mu   +10 more
doaj   +1 more source

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