Results 131 to 140 of about 60,645 (326)

Animation of UML-B State-machines

open access: yes
Animation is important because it allows the modeller to validate that a model behaves as intended. Visualisation of animations assists the modeller in making this assessment.
Snook, Colin   +2 more
core  

Atrial natriuretic peptide counteracts aldosterone secretion by preventing acute angiotensin II‐induced cAMP signalling

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Aldosterone plays a key role in blood pressure and volume regulation. Enhanced aldosterone secretion contributes to cardiovascular and renal diseases. Therefore, inhibitors of aldosterone receptors and synthase are essential drugs for the treatment of hypertension and heart failure.
Sanika Mohagaonkar   +6 more
wiley   +1 more source

Derived classes as a basis for views in UML/OCL data models

open access: yes
UML is the de facto standard language for analysis and design in object-oriented frameworks. Information systems, and in particular information systems based on databases and their applications, rely heavily on sound principles of analysis and design ...
Balsters, H.
core  

Comprehensibility of UML-based Formal Model – A Series of Controlled Experiments

open access: yes, 2007
This paper summarises two controlled experiments conducted on a model that integrates the use of semi-formal notation, the Unified Modelling Language (UML) and a formal notation, B.
Razali, R   +2 more
core  

Cellular Morphometric Analysis (CellMorph)—a comprehensive imaging‐based tool for quantifying cellular phenotype heterogeneity and dynamics across biological processes

open access: yesThe FEBS Journal, EarlyView.
CellMorph is a groundbreaking tool that allows researchers to analyze multiple features from single cells, including cell size and shape, cytosolic staining and subcellular texture, nuclear staining, and morphometry. By evaluating images from both bright‐field and fluorescence microscopy, it also tracks changes in living cells during key processes such
Henrique Quaiato de Oliveira   +16 more
wiley   +1 more source

Applying the UML to the ODP Enterprise Viewpoint [PDF]

open access: yes, 1999
Now that the Reference Model for Open Distributed Processing (RM-ODP) has stabilised, attention is shifting towards the definition of specific notations for the ODP viewpoints. The objective of this paper is twofold.
Derrick, John   +3 more
core  

UML-based Model Driven Development

open access: yes, 2018
The Unified Modeling Language (UML) is the “de jure” and “de facto” standard modeling language for software systems. It has been updated regularly since its inception, is being taught in universities all over the world and has been used extensively as a ...
Brito e Abreu, Fernando   +1 more
core   +1 more source

Regulation of PHOX2B gene expression by the long non‐coding natural antisense RNA PHOX2B‐AS1

open access: yesThe FEBS Journal, EarlyView.
PHOX2B is a transcription factor essential for autonomic nervous system development. We identify and characterize PHOX2B‐AS1, a human long non‐coding antisense transcript at the PHOX2B locus, along with its murine counterpart. Our findings reveal bidirectional transcription and reciprocal regulation: PHOX2B activates PHOX2B‐AS1, whereas PHOX2B‐AS1 ...
Simona Di Lascio   +12 more
wiley   +1 more source

The Chilean Waiting List sub-Corpus with medical entities normalized to UMLS terminology

open access: green, 2023
Pablo Báez   +5 more
openalex   +1 more source

Selective targeting of cortactin tandem repeat acetylation by human lysine deacetylases

open access: yesThe FEBS Journal, EarlyView.
Cortactin function is regulated by acetylation at several lysine residues within its tandem repeat region. Using genetic code expansion to generate cortactin variants containing precisely defined acetylation marks, we show that HDAC6 is the primary enzyme removing these modifications, with SIRT1 and SIRT2 also acting at selected sites but with lower ...
Jan Komarek   +12 more
wiley   +1 more source

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