Results 151 to 160 of about 193,599 (260)

An extensible formal semantics for UML activity diagrams [PDF]

, 2016
Zamira Daw, Rance Cleaveland
openalex   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, Volume 599, Issue 21, Page 3103-3112, November 2025.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

C‐mannosylation promotes ADAMTS1 activation and secretion in human testicular germ cell tumor NEC8 cells

FEBS Letters, Volume 599, Issue 21, Page 3113-3123, November 2025.
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi, Takehiro Suzuki, Ryota Kawahara, Natsumi Harai, Naoshi Dohmae, Siro Simizu   +5 more
wiley   +1 more source

Modeling of Traffic Accident Reporting System through UML Using GIS [PDF]

, 2012
Gufran, M.
openalex   +1 more source

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, Volume 599, Issue 21, Page 3047-3065, November 2025.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source

El juego de la consistencia: una estrategia didáctica para la ingeniería de software

Revista Técnica de la Facultad de Ingeniería
La enseñanza de la ingeniería de software se ha abordado tradicionalmente con métodos convencionales como clases magistrales y proyectos prácticos. Estas estrategias, si bien han permitido la formación de profesionales en esta área durante las últimas ...
Carlos Mario Zapata Jaramillo, Mary Inés Duarte Herrera   +1 more
doaj  

Uncovering Phenotypes in Sensorineural Hearing Loss: A Systematic Review of Unsupervised Machine Learning Approaches. [PDF]

Ear Hear
Dimitrov L, Barrett L, Chaudhry A, Muzaffar J, Lilaonitkul W, Mehta N.   +5 more
europepmc   +1 more source

UML-based conceptual design approach for modeling complex processes in web application [PDF]

, 2016
Siti Azreena Mubin, Azrul Hazri Jantan, Rusli Abdullah, Azrina Kamaruddin   +3 more
openalex  

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, Volume 19, Issue 11, Page 3409-3426, November 2025.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

Phytochemicals and antioxidant activity of leaf extract and callus cultures of Cinnamomum camphora L. [PDF]

PLoS One
Rasool S, Rasool K, Khilji SA, Sajid ZA.
europepmc   +1 more source