Results 61 to 70 of about 193,599 (260)

Leveraging Container Technologies in a GIScience Project: A Perspective from Open Reproducible Research

open access: yesISPRS International Journal of Geo-Information, 2020
Scientific reproducibility is essential for the advancement of science. It allows the results of previous studies to be reproduced, validates their conclusions and develops new contributions based on previous research.
Benito M. Zaragozí   +2 more
doaj   +1 more source

Vertical distribution and composition of phytoplankton under the influence of an upper mixed layer

open access: yes, 2010
The vertical distribution of phytoplankton is of fundamental importance for the dynamics and structure of aquatic communities. Here, using an advection-reaction-diffusion model, we investigate the distribution and competition of phytoplankton species in ...
Blasius, Bernd   +2 more
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Design Environments for Complex Systems [PDF]

open access: yes, 2003
The paper describes an approach for modeling complex systems by hiding as much formal details as possible from the user, still allowing verification and simulation of the model.
Priami, Corrado
core  

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

The UML model of business intelligence system in increasing corporate performance [PDF]

open access: yesStrategic Management, 2014
In the new environment of open economy and high competitiveness on the market of products and services, the operation of companies must be based on information-based structure.
Zdraveski Dejan   +2 more
doaj  

Implementasi Ekonomi Melingkar pada Sistem Informasi Pengelolaan Hutan Mangrove

open access: yesJEPIN (Jurnal Edukasi dan Penelitian Informatika), 2019
Penelitian ini bertujuan membangun sebuah sistem berbasis komputer yang dapat membantu pengelolaan hutan mangrove dengan menadopsi konsep ekonomi melingkar (Circular Economy).
Eva Faja Ripanti
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

COSMIC FPA CALCULATOR FOR MOBILE APPLICATION DEVELOPMENT COST BASED ON UNITY3D GAME ENGINE

open access: yesMalaysian Journal of Computing, 2014
The emergence technology and popularity of mobile game application has led to higher demands in producing more colorful game environment, interactive design and selecting targeted platforms.
Nur Atiqah Sia Abdullah   +1 more
doaj   +1 more source

Specification of vertical semantic consistency rules of UML class diagram refinement using logical approach [PDF]

open access: yes, 2014
Unified Modelling Language (UML) is the most popular modelling language use for software design in software development industries with a class diagram being the most frequently use diagram.
Nuraini Abdulganiyyi, Nuraini
core  

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