Results 81 to 90 of about 5,243 (226)
Ilkom Jurnal Ilmiah, 2017 Proses praktikum di Laboratorium Terpadu Fakultas Ilmu Komputer UMI adalah salah satu komponen vital dalam kegiatan belajar mengajar di Fakultas Ilmu Komputer UMI.
Hajrah Mansyur, Ichroman Raditya Duwila
doaj +1 more source
The FEBS Journal, EarlyView.Pyridoxal 5′‐phosphate (PLP) homeostasis relies on salvage enzymes, yet key metabolic branches remain undefined. We identify AKR1C isozymes as previously undescribed contributors that convert pyridoxal into pyridoxine or 4‐pyridoxolactone through reductase and dehydrogenase activities.
Nayu Kito +8 more
wiley +1 more source
The FEBS Journal, EarlyView.Human NAD(P)H:quinone oxidoreductase 1 is a homodimeric flavoenzyme crucial for redox metabolism and linked to significant health issues. Point mutations at Tyr126 and Tyr128 demonstrate their essential roles in optimizing substrate binding geometry for catalysis, as well as in half‐site reactivity and conformational dynamics during the enzyme's ...
Maribel Rivero +8 more
wiley +1 more source
The FEBS Journal, EarlyView.TGF‐β signaling regulates extracellular vesicle (EV) release in cancer cells by modulating the expression and activity of genes associated with EV biogenesis. The TGF‐β‐induced upregulation of RAB4A expression facilitates fast endosomal recycling, a process that limits the fusion of multivesicular bodies with the plasma membrane and EV secretion. Hence,
Dorival Mendes Rodrigues‐Junior +5 more
wiley +1 more source
The FEBS Journal, EarlyView.The role of PARs in platelet function is fairly known; however, the underlying mechanisms are not fully understood. We report that thrombin myristoylates PAR4 in mouse platelets and PAR1 and PAR4 in human platelets, facilitating their membrane transport and interaction, leading to PAR3/4 heterodimers in mice and PAR1/4 heterodimers in humans.
Suresh Govatati +4 more
wiley +1 more source
Long‐read sequencing‐based atlas of tissue‐specific expression of DNM1L transcript variants
The FEBS Journal, EarlyView.Targeted long‐read sequencing resolves full‐length DNM1L (Drp1) isoforms and reveals conserved, tissue‐specific expression patterns across human and mouse tissues. Functional assays show that Drp1 isoforms differ in their ability to drive mitochondrial fission, independent of abundance, with specific exons modulating activity.
Feng Yan +19 more
wiley +1 more source
ЦИФРОВАЯ ТРАНСФОРМАЦИЯ ЭПИЗООТОЛОГИЧЕСКОГО МОНИТОРИНГА — ПРИМЕР УСПЕШНОГО ВНЕДРЕНИЯ
Cifra: Медико-биологические наукиОдной из важнейших задач эпидемиологического надзора в целом и эпизоотологического мониторинга в частности является прогнозирование эпидемического процесса, эпизоотий среди резервуарных хозяев, возможных вспышек среди населения как актуальных, так и ...
Беднарская Е.В. +3 more
doaj +1 more source
Adipocyte‐specific NIK depletion enhances energy metabolism and glucose tolerance in mice
The FEBS Journal, EarlyView.Obesity is associated with reduced energy expenditure and increased hepatic lipid accumulation. This study reveals that loss of NIK in adipocytes stimulates FGF21‐driven expression of thermogenic genes, including UCP1, and mitochondrial uncoupled respiration.
Atakan Ozcan +8 more
wiley +1 more source
Análise do uso da cor no Diagrama de Classes da Linguagem Unificada de Modelagem (UML)
InfoDesign: Brazilian Journal of Information Design, 2020 O uso da cor em diagramas na Engenharia de Software não é novidade, em especial na Linguagem Unificada de Modelagem (UML), que consiste em um conjunto de quinze diagramas utilizados para documentar e especificar a complexidade de um software.
Rodrigo Diego de Oliveira
doaj
The FEBS Journal, EarlyView.Macromolecule‐dependent increases in extracellular fluid viscosity alter cell phenotype. These distinct macromolecules create different extracellular environments that modulate cell morphology and mechanoprotein expression, migration and invasion capacity, and cellular mechanical properties.
Ian M. Smith +6 more
wiley +1 more source