Results 101 to 110 of about 60,497 (198)

GMP‐compliant production, validation and dosimetry of clinical grade [18F]3‐(3‐fluoropropyl)‐2‐phenyl‐2,3‐dihydrobenzo[d]thiazole ([18F]FPBT) for oxidative stress PET imaging

British Journal of Pharmacology, Volume 183, Issue 20, Page 6028-6045, October 2026.
Background and Purpose Oxidative stress plays a critical role in the pathophysiology of various diseases, yet current methods for its non‐invasive detection remain limited. This study aimed to systematically validate a superoxide‐selective PET tracer, [18F]FPBT, for the early diagnosis and therapeutic monitoring of oxidative stress‐related conditions ...
Hua Zhang, Fangfang Sun, Chun Li, Xin Wang, Yuexuan Song, Lu Jiang, Paul Gape, Samantha Y. A. Terry, Shujun He, Ran Yan, Zhi Lu   +10 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, Volume 20, Issue 9, Page 2280-2295, September 2026.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

UML-B Survey Questionnaires and Responses

, 2007
This document contains the questionnaires and responses of the survey conducted on the UML-B method. The survey assessed the usability of the method, particularly the notation used, from the developers’ perspective.
Razali, R
core   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, Volume 20, Issue 9, Page 2323-2339, September 2026.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

ЦИФРОВАЯ ТРАНСФОРМАЦИЯ ЭПИЗООТОЛОГИЧЕСКОГО МОНИТОРИНГА — ПРИМЕР УСПЕШНОГО ВНЕДРЕНИЯ

Cifra: Медико-биологические науки
Одной из важнейших задач эпидемиологического надзора в целом и эпизоотологического мониторинга в частности является прогнозирование эпидемического процесса, эпизоотий среди резервуарных хозяев, возможных вспышек среди населения как актуальных, так и ...
Беднарская Е.В., Двирский А.А., Головатюк А.С., Проскурнин Р.В.   +3 more
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, Volume 16, Issue 9, Page 1645-1656, September 2026.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Análise do uso da cor no Diagrama de Classes da Linguagem Unificada de Modelagem (UML)

InfoDesign: Brazilian Journal of Information Design, 2020
O uso da cor em diagramas na Engenharia de Software não é novidade, em especial na Linguagem Unificada de Modelagem (UML), que consiste em um conjunto de quinze diagramas utilizados para documentar e especificar a complexidade de um software.
Rodrigo Diego de Oliveira
doaj  

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, Volume 16, Issue 9, Page 1813-1824, September 2026.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Applying UML : advanced application /

, 2004
An indispensible guide to applying UML in real world situations.Includes bibliographical references and index.Cover; Copyright Page; TOCContents; Preface; Who Should Read This Book?; What This Book Is Not; How Should You Use This Book?; Supplementary ...
Pooley, R. J., Wilcox, Pauline.
core  

Unraveling the Spatiotemporal Dynamics and Nonlinear Drivers of Green Transition of Farmland Use in Major Grain‐Producing Areas: A Case Study of Jiangsu Province, China

Land Degradation &Development, Volume 37, Issue 15, Page 10851-10872, September 2026.
ABSTRACT Promoting the green transition of farmland use (GTFU) in major grain‐producing areas is essential for ensuring food security and advancing sustainable agricultural development. However, existing studies on GTFU have predominantly relied on static cross‐sectional analyses, with insufficient attention paid to its nonlinear driving mechanisms. To
Zhixian Sun, Yixuan Lu, Xinyue Zheng, Dongmei Zhang, Yian Xu, Guanxin Yao   +5 more
wiley   +1 more source