Results 61 to 70 of about 1,008 (206)

Model‐Based Systems Engineering in Space Applications: A Comprehensive Literature Review

Systems Engineering, EarlyView.
ABSTRACT The growing complexity of space engineering is driving the demand to embrace the adoption of Model‐Based Systems Engineering (MBSE). Although the MBSE is well‐practiced in the space industry, the level of effort and need required to obtain the benefits of MBSE vastly differ across enterprises; this disparity presents a significant challenge to
Rehobot Bekele Buruso, Sara Himmiche, Taiwo Tejumola, Yeshirun Alemayehu, Bertrand Rose   +4 more
wiley   +1 more source

Dependability Modeling and Assessment in UML-Based Software Development

The Scientific World Journal, 2012
Assessment of software nonfunctional properties (NFP) is an important problem in software development. In the context of model-driven development, an emerging approach for the analysis of different NFPs consists of the following steps: (a) to extend the ...
Simona Bernardi, José Merseguer, Dorina C. Petriu   +2 more
doaj   +1 more source

A Framework for Web Applications using an Agile and Collaborative Model Driven Development (AC-MDD)

Acta Scientiarum: Technology, 2019
This paper presents, as its main contribution, a Framework for Web Applications named Agile and Collaborative Model Driven Development (AC-MDD). It aims to increase productivity by generating source-codes from agile models. It tackles the waste reduction
Breno Lisi Romano, Adilson Marques da Cunha   +1 more
doaj   +1 more source

Extending SysML v2 for Safety ‐ Open‐Source Library for the System‐Theoretic Process Analysis

Systems Engineering, EarlyView.
ABSTRACT Safety challenges in automated transport systems create the need for a strong design and safety coupling. In this regard, the second version of the Systems Modeling Language (SysML v2) offers new integration opportunities with extensibility features such as libraries.
Alexander Ahlbrecht, Florian Wagner, Umut Durak   +2 more
wiley   +1 more source

Assessment of a Model‐Based Approach to Achieve Authorization to Operate

Systems Engineering, EarlyView.
ABSTRACT Accreditation of United States Government (USG) Information Systems (IS) is required to assure their function and security before delivery to the operational environment. However, in many cases, the baseline document‐based accreditation processes are sources of cost and schedule overruns.
Edan C. Sanchez, John M. “Mike” Borky, Thomas H. Bradley   +2 more
wiley   +1 more source

Impacts of Change‐Type and State‐Type System Qualities on Complex System Architectures

Systems Engineering, EarlyView.
ABSTRACT System qualities, such as scalability, expandability, and reconfigurability, are key requirements of complex systems. Requirements associated with system qualities are important factors in design trade space analyses, but systems engineering design methodologies make only limited use of these qualities, hindering a holistic understanding of ...
Christina F. Bridges, Benjamin W. Stirgwolt   +1 more
wiley   +1 more source

Therapeutic potential of a Bax inhibitor‐1/TMBIM6 antagonist (BIA) and its analogues in Aspergillus fumigatus‐induced asthma via dual targeting of AKT and epithelial‐derived inflammatory cytokines

British Journal of Pharmacology, EarlyView.
Background and Purpose Aspergillus fumigatus (A. fumigatus) exposure causes of severe allergic asthma, characterized by airway inflammation and epithelial dysfunction. TMBIM6 (Bax inhibitor‐1) has been implicated in airway epithelial stress responses and AKT signalling.
Young‐Jin Yu, Ahsan Ullah, Jisun Kim, Mehedi Hasan Bappi, Yerim Heo, Jin Hee Ahn, Hyun‐Kyoung Kim, Han‐Jung Chae   +7 more
wiley   +1 more source

Modelando con UML el proceso de evaluación de productos de software utilizando el enfoque GQM

Revista Cubana de Ciencias Informáticas, 2015
El enfoque GQM (Meta-Pregunta-Métrica, por sus siglas en inglés) ha sido utilizado en el proceso de evaluación de calidad de productos de software, como instancia de un paradigma de medida.
José Ramón Hernández Vega, Sandra Verona Marcos, Sonia Pérez Lovelle   +2 more
doaj  

Knowledge Modelling Using The UML Profile [PDF]

, 2006
This paper discusses platform independent conceptual modeling of a knowledge intensive application, focusing on the use of knowledge-based systems (KBS) in the context of model-driven engineering. An extension to the Unified Modeling Language (UML) for knowledge modeling is presented based on the profiling extension mechanism of UML.
Mohd Syazwan Abdullah, Richard F. Paige, Ian D. Benest, Chris Kimble   +3 more
openaire   +2 more sources

GMP‐compliant production, validation and dosimetry of clinical grade [18F]3‐(3‐fluoropropyl)‐2‐phenyl‐2,3‐dihydrobenzo[d]thiazole ([18F]FPBT) for oxidative stress PET imaging

British Journal of Pharmacology, EarlyView.
Background and Purpose Oxidative stress plays a critical role in the pathophysiology of various diseases, yet current methods for its non‐invasive detection remain limited. This study aimed to systematically validate a superoxide‐selective PET tracer, [18F]FPBT, for the early diagnosis and therapeutic monitoring of oxidative stress‐related conditions ...
Hua Zhang, Fangfang Sun, Chun Li, Xin Wang, Yuexuan Song, Lu Jiang, Paul Gape, Samantha Y. A. Terry, Shujun He, Ran Yan, Zhi Lu   +10 more
wiley   +1 more source