Results 81 to 90 of about 1,008 (206)

Perancangan Aplikasi Tes Bahasa Inggris Online (ATBIO) dengan Soal Acak

open access: yesComTech, 2011
English proficiency can be measured through several tests that are recognized internationally like TOEFL. To measure the English proficiency of ‘Binusians’ with TOEFL standards and provide rapid and credible test results, an program design of online
Hady Pranoto
doaj   +1 more source

Exploring Disulfide Bridge as a Tool to Improve Pioglitazone’s Neuroprotective Potential: Toward the Development of Prolonged‐Acting MAO‐B/PPARγ Modulators

open access: yesChemMedChem, Volume 21, Issue 15, 14 August 2026.
Pioglitazone is an antidiabetic drug acting as a peroxisome proliferator‐activated receptor γ (PPARγ) agonist and later repositioned as a monoamine oxidase B (MAO‐B) inhibitor. Despite promising preclinical premises, it showed a lack of efficacy in clinical trials as a treatment for neurodegenerative diseases.
Filippo Basagni   +12 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, Volume 600, Issue 15, Page 2175-2192, August 2026.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, Volume 600, Issue 15, Page 2094-2107, August 2026.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

UML in business process modeling

open access: yesContemporary Economy, 2013
Selection and proper application of business process modeling methods and techniques have a significant impact on organizational improvement capabilities as well as proper understanding of functionality of information systems that shall support activity ...
Bartosz Marcinkowski
doaj  

Conceptual design and implementation of spatial data warehouses integrating regular grids of points

open access: yesInternational Journal of Digital Earth, 2017
Spatial online analytical processing (OLAP) and spatial data warehouse (SDW) systems are geo-business intelligence technologies that enable the analysis of huge volumes of geographic data.
Sandro Bimonte   +2 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, Volume 20, Issue 8, Page 1963-1985, August 2026.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

A profile’s design for parallel applications modelling

open access: yesRevista Colombiana de Computación, 2010
During the last times hardware progress has reached home computers with technologies that were only used in main frames. Clear examples of this statement are multiple core personal computers.
Daniel Alberto Giulianelli   +4 more
doaj  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, Volume 20, Issue 8, Page 2085-2101, August 2026.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Modeling of embedded software on MDA platform models

open access: yesJournal of Computer Science and Technology, 2012
This study proposes the use of abstract software models in order to meet the diversity of embedded platforms. A UML 2.0 Profile for Modeling Application and Platform of Embedded Software (called PROAPES) is proposed.
Inali Wisniewski Soares   +3 more
doaj  

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