Brain-derived neurotrophic factor levels in newly diagnosed patients with bipolar disorder, their unaffected first-degree relatives and healthy controls [PDF]
BJPsych Open, 2021 Background Brain-derived neurotrophic factor (BDNF), which facilitates neuroplasticity and synaptogenesis, may be decreased in bipolar disorder, but has not been systematically investigated in people with newly diagnosed bipolar disorder and unaffected ...
Nanna Aagaard Petersen +10 more
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Functional Alterations in Patients with Bipolar Disorder and Their Unaffected First-Degree Relatives: Insight from Genetic, Epidemiological, and Neuroimaging Data [PDF]
Neuropsychiatric Disease and Treatment, 2023 Haonan Zhang,1 Jun Chen,1,2 Yiru Fang1– 4 1Clinical Research Center, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 2Shanghai Key Laboratory of Psychotic Disorders, Shanghai, People ...
Zhang H, Chen J, Fang Y
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Serum BDNF levels in unaffected first-degree relatives of patients with bipolar disorder [PDF]
Brazilian Journal of Psychiatry, 2016 Objective: Unaffected relatives of bipolar disorder (BD) patients have been investigated for the identification of endophenotypes in an attempt to further elucidate the pathophysiology of the disease.
Fabiano G. Nery +9 more
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Error-Related Brain Activity in Patients With Obsessive-Compulsive Disorder and Unaffected First-Degree Relatives: Evidence for Protective Patterns [PDF]
Biological Psychiatry Global Open Science, 2022 Background: Indicators of increased error monitoring are associated with obsessive-compulsive disorder (OCD), as shown in electroencephalography and functional magnetic resonance imaging studies.
Rosa Grützmann +9 more
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Spatial working memory performance in people with obsessive–compulsive disorder, their unaffected first-degree relatives and healthy controls [PDF]
BJPsych Open, 2021 Studies have shown that people with obsessive–compulsive disorder (OCD) have impairments in spatial working memory (SWM) performance. However, it remains unclear whether this deficit represents a cognitive endophenotype preceding symptoms or a correlate ...
Stephan Heinzel +8 more
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Facial emotion-recognition deficits in patients with schizophrenia and unaffected first-degree relatives [PDF]
Frontiers in PsychiatryIntroductionThis study aimed to determine trait- and state-dependent markers of schizophrenia by investigating facial emotion-recognition (FER) deficits in remitted patients with schizophrenia and their first-degree relatives (FR).MethodsThree groups ...
Minjae Bae +5 more
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SAGE Open, 2012 The study aims to evaluate the neuropsychological functions of unaffected first-degree relatives of patients with bipolar disorder Type I (BD-I) in comparison with healthy controls. The method was a cross-sectional assessment of 20 first-degree relatives
Raman Deep Pattanayak +2 more
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Metabolic profile in patients with newly diagnosed bipolar disorder and their unaffected first-degree relatives [PDF]
International Journal of Bipolar Disorders, 2019 Objective The prevalence of metabolic syndrome and insulin resistance is twice as high in patients with bipolar disorder compared with the general population, and possibly associated with a disabling illness trajectory of bipolar disorder, an increased ...
Klara Coello +6 more
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Pro-inflammatory cytokine alterations in unaffected first-degree relatives of schizophrenia patients [PDF]
European Psychiatry, 2021 Introduction A growing body of evidence in both chronic and first-episode schizophrenia report increased expression of pro-inflammatory substances in the blood and cerebrospinal fluid of patients.
A. Kurtulmus
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Characteristics of Multimodal Brain Connectomics in Patients With Schizophrenia and the Unaffected First-Degree Relatives [PDF]
Frontiers in Cell and Developmental Biology, 2021 ObjectiveIncreasing pieces of evidence suggest that abnormal brain connectivity plays an important role in the pathophysiology of schizophrenia. As an essential strategy in psychiatric neuroscience, the research of brain connectivity-based neuroimaging ...
Xiao Lin +10 more
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