Aberrant rich club organization in patients with obsessive-compulsive disorder and their unaffected first-degree relatives [PDF]
NeuroImage: Clinical, 2021 Recent studies suggested that the rich club organization promoting global brain communication and integration of information, may be abnormally increased in obsessive-compulsive disorder (OCD).
Ziwen Peng +8 more
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The effects of childhood trauma on personality in unaffected first-degree relatives of patients with major depressive disorder [PDF]
BMC Psychiatry, 2022 Abstrac Objectives This study aimed to preliminarily and exploratorily examine the associations between childhood trauma (CT), its subtypes, and personality traits among unaffected first-degree relatives (FDR, children, or siblings) of patients with ...
Yu-jie Wen +10 more
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Familial load of psychiatric disorders and overall functioning in patients newly diagnosed with bipolar disorder and their unaffected first-degree relatives [PDF]
International Journal of Bipolar Disorders, 2022 Background Overall functioning is already impaired in patients newly diagnosed with bipolar disorder (BD) and, to a lesser degree, also in their unaffected first-degree relatives (UR).
Kimie Stefanie Ormstrup Sletved +4 more
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Neurocognitive impairments in unaffected first-degree relatives of schizophrenia [PDF]
Indian Journal of Psychological Medicine, 2017 Background: Neurocognitive impairments of attention and executive functioning are trait abnormalities in schizophrenia, and these are considered to be endophenotypes. These deficits have been convincingly linked to prefrontal cortical functioning.
Virupaksha Shanmugam Harave +5 more
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Exome sequencing of multiple-sclerosis patients and their unaffected first-degree relatives [PDF]
BMC Research Notes, 2017 Objectives The understanding of complex multifactorial diseases requires the availability of a variety of data for a large-number of affected individuals.
Sheila Garcia-Rosa +11 more
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Convergent and divergent gray matter volume abnormalities in unaffected first-degree relatives and ultra-high risk individuals of schizophrenia [PDF]
npj Schizophrenia, 2022 High-risk populations of schizophrenia can be mainly identified as genetic high-risk based on putative endophenotypes or ultra-high-risk (UHR) based on clinically manifested symptoms.
Bei Lin +6 more
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Subjective Cognitive Complaints in Unaffected First-Degree Relatives of Schizophrenia Patients: Relation to Cognitive Performance, Psychotic Experiences, and Social Functioning [PDF]
Indian Journal of Psychological Medicine, 2022 Background: Neurocognitive deficits are well-documented in patients of schizophrenia and their first-degree relatives (FDRs). Metacognitive awareness of these deficits, called neurocognitive insight (NI), has been found to be poor in schizophrenia ...
Sachin P Baliga +3 more
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Personality traits in adults with attention-deficit hyperactivity disorder and their unaffected first-degree relatives [PDF]
BJPsych Open, 2016 Background Attention-deficit hyperactivity disorder (ADHD) shows clear, albeit heterogeneous, cognitive dysfunctions.
Valentino Antonio Pironti +4 more
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PLoS ONE, 2011 BackgroundMinor physical anomalies (MPAs) have been found to be more prevalent in schizophrenia than control participants in numerous studies and may index a potential endophenotype for schizophrenia.AimTo quantitatively define the magnitude of the ...
Ting Xu +2 more
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Autistic traits in unaffected first-degree relatives of individuals with schizophrenia and bipolar disorder: implications for shared familial neurodevelopmental vulnerability [PDF]
Frontiers in PsychiatryBackgroundAutistic traits have increasingly been linked to schizophrenia (SCH) and bipolar disorder (BD) within a shared neurodevelopmental framework.
Fatma Büşra Parlakkaya Yıldız +4 more
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