Results 51 to 60 of about 4,223,424 (298)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

A Data-Driven Approach to Revolutionize Children’s Vaccination with the Use of VR and a Novel Vaccination Protocol

open access: yesBioMedInformatics
Background: This study aims to revolutionize traditional pediatric vaccination protocols by integrating virtual reality (VR) technology. The purpose is to minimize discomfort in children, ages 2–12, during vaccinations by immersing them in a specially ...
Stavros Antonopoulos   +2 more
doaj   +1 more source

Uncertainty and Monetary Policy Rules in the United States [PDF]

open access: yes, 2005
This paper analyses the impact of uncertainty about the true state of the economy on monetary policy rules in the US since the early 1980s. Extending the Taylor rule to allow for this type of uncertainty, we find evidence that the predictions of the ...
Martin, C, Milas, C
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Optimal Uncertainty Quantification [PDF]

open access: yes, 2010
We propose a rigorous framework for Uncertainty Quantification (UQ) in which the UQ objectives and the assumptions/information set are brought to the forefront.
McKerns, M.   +4 more
core  

A Labelling Framework for Probabilistic Argumentation

open access: yes, 2018
The combination of argumentation and probability paves the way to new accounts of qualitative and quantitative uncertainty, thereby offering new theoretical and applicative opportunities.
Baroni, Pietro   +5 more
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

A Direct Eulerian GRP Scheme for the Prediction of Gas-Liquid Two-Phase Flow in HTHP Transient Wells

open access: yesAbstract and Applied Analysis, 2013
A coupled system model of partial differential equations is presented in this paper, which concerns the variation of the pressure and temperature, velocity, and density at different times and depths in high temperature-high pressure (HTHP) gas-liquid two-
Jiuping Xu   +5 more
doaj   +1 more source

Uncertain About Uncertainty: How Qualitative Expressions of Forecaster Confidence Impact Decision-Making With Uncertainty Visualizations

open access: yesFrontiers in Psychology, 2021
When forecasting events, multiple types of uncertainty are often inherently present in the modeling process. Various uncertainty typologies exist, and each type of uncertainty has different implications a scientist might want to convey.
Lace M. K. Padilla   +3 more
doaj   +1 more source

Uncertainty quantification (UQ) [PDF]

open access: yes, 2011
This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
3rd Micro and Nano Flows Conference (MNF2011)   +1 more
core  

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