Results 51 to 60 of about 1,471,470 (312)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi +5 more
wiley +1 more source
Molecular Oncology, Volume 20, Issue 6, Page 1626-1642, June 2026.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, Volume 20, Issue 6, Page 1453-1472, June 2026.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
CORE: Cultivation of Collaboration Skills via Educational Robotics
KnowledgeCollaboration skills are an important component of 21st century skills and a critical skill for citizens of the future. In this work, we propose collaboration-oriented robotics education (CORE), a methodology aimed at fostering the development of ...
Emmanouil A. Demetroulis +4 more
doaj +1 more source
Entropy, 2008 We give a survey of the basic statistical ideas underlying the definition of entropy in information theory and their connections with the entropy in the theory of dynamical systems and in statistical mechanics.
openaire +3 more sources
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Differentiated Education Using Technology in Junior and High School Classrooms
EncyclopediaThis entry presents the findings of a bibliographic review in Differentiated Instruction (DI), emphasizing its importance in classrooms with diverse student abilities.
Elissavet Spyropoulou +2 more
doaj +1 more source
Uncertainty as Unavoidable Good
, 2023 Piotrowski M. Uncertainty as Unavoidable Good. Center for Uncertainty Studies Working Papers. Vol 5. Bielefeld: Universität Bielefeld, Center for Uncertainty Studies (CeUS); 2023.In digital history, uncertainty is generally regarded as an unavoidable ...
Piotrowski, Michael
core +1 more source
Fluctuations in Uncertainty [PDF]
SSRN Electronic Journal, 2013 In this essay, the author addresses four questions about uncertainty. First, what are some facts and patterns about economic uncertainty? Both macro and micro uncertainty appear to rise sharply in recessions and fall in booms. Uncertainty also varies heavily across countries - developing countries appear to have about one-third more macro uncertainty ...
openaire +5 more sources
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source