Results 41 to 50 of about 85,519 (230)

Different antibiotic growth promoters induce specific changes in the cecal microbiota membership of broiler chicken.

PLoS ONE, 2017
Antimicrobials are sometimes given to food animals at low doses in order to promote faster growth. However, the mechanisms by which those drugs improve performance are not fully understood.
Marcio C Costa, Jose A Bessegatto, Amauri A Alfieri, J Scott Weese, João A B Filho, Alexandre Oba   +5 more
doaj   +1 more source

Update and elucidation of Plasmodium kinomes: Prioritization of kinases as potential drug targets for malaria

Computational and Structural Biotechnology Journal, 2022
Malaria is a tropical disease caused by Plasmodium spp. and transmitted by the bite of infected Anopheles mosquitoes. Protein kinases (PKs) play key roles in the life cycle of the etiological agent of malaria, turning these proteins attractive targets ...
Joyce Villa Verde Bastos Borba, Arthur de Carvalho e Silva, Marília Nunes do Nascimento, Letícia Tiburcio Ferreira, Aline Rimoldi, Luísa Starling, Pablo Ivan Pereira Ramos, Fabio Trindade Maranhão Costa, Carolina Horta Andrade   +8 more
doaj   +1 more source

Measuring antibiotic availability and use in 20 low- and middle-income countries [PDF]

, 2020
Objective To assess antibiotic availability and use in health facilities in low- and middle-income countries, using the service provision assessment and service availability and readiness assessment surveys.
Hsia, Y, Knowles, R, Magrini, N, Moja, L, Sharland, M, Siyam, A, Tayler, E   +6 more
core   +2 more sources

Marine Sponge and Octocoral-Associated Bacteria Show Versatile Secondary Metabolite Biosynthesis Potential and Antimicrobial Activities against Human Pathogens

Marine Drugs, 2022
Marine microbiomes are prolific sources of bioactive natural products of potential pharmaceutical value. This study inspected two culture collections comprising 919 host-associated marine bacteria belonging to 55 genera and several thus-far unclassified ...
João F. Almeida, Matilde Marques, Vanessa Oliveira, Conceição Egas, Dalila Mil-Homens, Romeu Viana, Daniel F. R. Cleary, Yusheng M. Huang, Arsénio M. Fialho, Miguel C. Teixeira, Newton C. M. Gomes, Rodrigo Costa, Tina Keller-Costa   +12 more
doaj   +1 more source

Analysis of the Effects of Dietary Pattern on the Oral Microbiome of Elite Endurance Athletes [PDF]

, 2019
Although the oral microbiota is known to play a crucial role in human health, there are few studies of diet x oral microbiota interactions, and none in elite athletes who may manipulate their intakes of macronutrients to achieve different metabolic ...
Burke, Louise M, Campbell, Katrina L, Charlesson, Bronwen, Krause, Lutz, Morrison, Mark, Murtaza, Nida, O'Neill, Hayley M, Ross, Megan L, Vlahovich, Nicole   +8 more
core   +3 more sources

Review: Comparing drug treatments in epilepsy

Therapeutic Advances in Neurological Disorders, 2009
The great majority of randomised controlled trials (RCTs) that compare antiepileptic drugs are industry sponsored and have the objective of obtaining a monotherapy license for a drug.
David Chadwick, Arif Shukralla, Tony Marson   +2 more
doaj   +1 more source

Metagenomic analysis of therapeutic PYO phage cocktails from 1997 to 2014 [PDF]

, 2017
Phage therapy has regained interest in recent years due to the alarming spread of antibiotic resistance. Whilst phage cocktails are commonly sold in pharmacies in countries such as Georgia and Russia, this is not the case in western countries due to ...
Kilstrup, Mogens, Larsen, Mette Voldby, Nielsen, Morten, Villarroel, Julia   +3 more
core   +3 more sources

Drug trends and harm related to new psychoactive substances (NPS) in Sweden from 2010 to 2016: Experiences from the STRIDA project.

PLoS ONE, 2020
BackgroundIn the past decade, hundreds of new psychoactive substances (NPS) have been introduced as unclassified alternatives to the illicit drugs.
Anders Helander, Matilda Bäckberg, Olof Beck   +2 more
doaj   +1 more source

Refractory Septic Shock due to Underlying Immunocompromised Disease: A Case of Fatal Peripheral T-Cell Lymphoma Not Otherwise Specified in a Young Hispanic Woman

Case Reports in Oncology, 2018
Peripheral T-cell lymphoma not otherwise specified (PTCL-NOS) is known as an unclassified group of non-Hodgkin lymphomas. PTCL-NOS is a subtype of peripheral T-cell lymphoma that accounts for 3% of all lymphomas in the United States.
Kishore Kumar, Muhammad Saad, Chukwunonso Chime, Kanthi Badipatla, Hassan Tariq, Sureshkumar Nayudu, Masooma Niazi, Sridhar Chilimuri   +7 more
doaj   +1 more source

(Re)Defining the Proline-Rich Antimicrobial Peptide Family and the Identification of Putative New Members

Frontiers in Chemistry, 2020
As we rapidly approach a post-antibiotic era in which multi-drug resistant bacteria are ever-pervasive, antimicrobial peptides (AMPs) represent a promising class of compounds to help address this global issue.
Nicholas G. Welch, Nicholas G. Welch, Wenyi Li, Wenyi Li, Mohammed Akhter Hossain, Mohammed Akhter Hossain, Frances Separovic, Frances Separovic, Neil M. O'Brien-Simpson, Neil M. O'Brien-Simpson, John D. Wade, John D. Wade   +11 more
doaj   +1 more source