Results 21 to 30 of about 85,519 (230)
Genomic profiling and directed ex vivo drug analysis of an unclassifiable myelodysplastic/myeloproliferative neoplasm progressing into acute myeloid leukemia [PDF]
Genes, Chromosomes and Cancer, 2016 Myelodysplastic/myeloproliferative neoplasms, unclassifiable (MDS/MPN‐U) are rare genetically heterogeneous hematologic diseases associated with older age and a poor prognosis. If the disease progresses into acute myeloid leukemia (AML), it is often refractory to treatment.
Hyrenius-Wittsten, Axel +7 more
openaire +3 more sources
The potential negative impact of antibiotic pack on antibiotic stewardship in primary care in Switzerland: a modelling study. [PDF]
, 2020 BACKGROUND: In Switzerland, oral antibiotics are dispensed in packs rather than by exact pill-count. We investigated whether available packs support compliance with recommended primary care treatment regimens for common infections in children and adults.
Berger, C +5 more
core +3 more sources
Pharmaceuticals, 2021 Brivaracetam (BRV) is the latest approved antiepileptic drug. The aim of the study was to evaluate the efficacy and tolerability of BRV in everyday clinical practice.
Maria Stefanatou +11 more
doaj +1 more source
npj Breast Cancer, 2021 Breast cancer is heterogeneous in prognoses and drug responses. To organize breast cancers by gene expression independent of statistical methodology, we identified the Breast Cancer Consensus Subtypes (BCCS) as the consensus groupings of six different ...
Christina Horr, Steven A. Buechler
doaj +1 more source
PLoS ONE, 2020 IntroductionAntimicrobial use is associated with emergence of antimicrobial resistance. We report hospital antimicrobial procurement, as a surrogate for consumption in humans, expenditure and prices in public hospitals in Vietnam, a lower middle-income ...
Vu Quoc Dat +4 more
doaj +1 more source
Neuropharmacology of Antiseizure Drugs
Neuropsychopharmacology Reports, 2021 Background Antiseizure drugs (ASDs) are the primary therapy for epilepsy, with more than 20 drugs introduced into clinical practice to date. These drugs are typically grouped by their mechanisms of action and therapeutic spectrum.
Tahir Hakami
doaj +1 more source
The microbial community in the feces of the white rhinoceros (Ceratotherium simum) as determined by barcoded pyrosequencing analysis. [PDF]
PLoS ONE, 2013 As a non-ruminant herbivore, the white rhinoceros has the ability to utilize fibrous plant matter through microbial fermentation in the hindgut. So far, there has been no report using molecular techniques to study the gut microbiota of the white ...
Gaorui Bian, Li Ma, Yong Su, Weiyun Zhu
doaj +1 more source
Reflections on the US FDA's Warning on Direct-to-Consumer Genetic Testing [PDF]
Genomics & Informatics, 2014 In November 2013, the US Food and Drug Administration (FDA) sent a warning letter to 23andMe, Inc. and ordered the company to discontinue marketing of the 23andMe Personal Genome Service (PGS) until it receives FDA marketing authorization for the device.
Seon-Hee Yim, Yeun-Jun Chung
doaj +1 more source
BMC Research Notes, 2012 Background Diagnosis of amoebic liver abscess (ALA) in patients on anti-amoebic drugs is difficult. There is scanty data on this issue using Entamoeba histolytica (E. histolytica) lectin antigen and polymerase chain reaction (PCR).
Jaiswal Virendra +5 more
doaj +1 more source
Discovery of IL-18 as a novel secreted protein contributing to doxorubicin resistance by comparative secretome analysis of MCF-7 and MCF-7/Dox. [PDF]
PLoS ONE, 2011 BACKGROUND: Resistance to chemotherapy is the major cause of failure in breast cancer treatment. Recent studies suggest that secreted proteins may play important roles in chemoresistance.
Ling Yao +4 more
doaj +1 more source