Results 11 to 20 of about 85,519 (230)

Unclassified drug overdose deaths in the opioid crisis: emerging patterns of inequity [PDF]

Journal of the American Medical Informatics Association, 2019
Abstract Objective Examine whether individual, geographic, and economic phenotypes predict missing data on specific drug involvement in overdose deaths, manifesting inequities in overdose mortality data, which is a key data source used in measuring the opioid epidemic.
Andrew J Boslett, Alina Denham, Elaine L Hill, Meredith C B Adams   +3 more
europepmc   +5 more sources

Using contributing causes of death improves prediction of opioid involvement in unclassified drug overdoses in US death records [PDF]

Addiction, 2020
AbstractBackground and AimsA substantial share of fatal drug overdoses is missing information on specific drug involvement, leading to under‐reporting of opioid‐related death rates and a misrepresentation of the extent of the opioid epidemic. We aimed to compare methodological approaches to predicting opioid involvement in unclassified drug overdoses ...
Andrew J. Boslett, Alina Denham, Elaine L. Hill   +2 more
openaire   +3 more sources

Coroner county systems are associated with a higher likelihood of unclassified drug overdoses compared to medical examiner county systems

The American Journal of Drug and Alcohol Abuse, 2022
Background: There is a striking geographic variation in drug overdose deaths without a specific drug recorded, many of which likely involve opioids. Knowledge of the reasons underlying this variation is limited. Objectives: We sought to understand the role of medicolegal death investigation (MDI) systems in unclassified drug overdose mortality. Methods:
Alina, Denham, Tarsha, Vasu, Paloma, Avendano, Andrew, Boslett, Michael, Mendoza, Elaine L, Hill   +5 more
openaire   +4 more sources

BRAF mutations and targeted therapy in unclassified pericytic tumors: insights from genetic analysis and clinical response [PDF]

BMC Cancer
Background Pericytic tumors are a group of soft tissue neoplasms characterized by a hemangiopericytoma (HPC)-like pattern. The underlying genetic lesion of pericytic neoplasms is still obscure; however, recent advances in molecular pathology have enabled
Hana Golan, Moshe Leitner, Marilena Vered, Gahl Greenberg, Rinat Yacobi, Hilla Tabibian-Keissar, Amos Toren, Bella Bielorai, Gideon Rechavi, Ninette Amariglio, Iris Barshack, Ran Yahalom, Ariel Hirschhorn, Michal Yalon   +13 more
doaj   +2 more sources

Labeled NSAID hypersensitivity and the risk of opioid prescribing; an observational study [PDF]

Frontiers in Allergy
BackgroundNSAIDs are widely used for pain management but are second only to antibiotics in causing drug hypersensitivity reactions. Misclassification of these reactions often leads to unnecessary avoidance of the entire drug class, potentially resulting ...
Laila Carolina Abu Esba, Laila Carolina Abu Esba, Laila Carolina Abu Esba, Reham Alhoraibi, Salem Abu Al-Burak, Husam I. Ardah   +5 more
doaj   +2 more sources

Forensic postmortem findings for sudden unexplained death in schizophrenia: case series and literature review [PDF]

Frontiers in Psychiatry
IntroductionThere are currently limited autopsy-based studies on sudden unexplained death in patients with schizophrenia (SDU-SCZ).MethodsWe summarized the demographic data, autopsy characteristics, and postmortem antipsychotics result for a total of 152
Yuanyuan Chen, Fengping Yan
doaj   +2 more sources

The zebrafish in toxicology: a bibliometric analysis reveals current trends and future avenues for predictive safety assessment [PDF]

Frontiers in Toxicology
The zebrafish (Danio rerio) has become an indispensable model in toxicological research, bridging environmental monitoring, disease modeling, and preclinical drug screening.
Carla Lima, Darlan Gusso, Geonildo Rodrigo Disner, Felipe Justiniano Pinto, Maria Alice Pimentel Falcão, João Gabriel Santos Rosa, Mônica Lopes-Ferreira   +6 more
doaj   +2 more sources

Progressive fibrotic interstitial lung disease [PDF]

Jornal Brasileiro de Pneumologia, 2023
Many interstitial lung diseases (ILDs) share mechanisms that result in a progressive fibrosing phenotype. In Brazil, the most common progressive fibrosing interstitial lung diseases (PF-ILDs) are chronic hypersensitivity pneumonitis, idiopathic pulmonary
Carlos A C Pereira, Soraya Cordero, Ana Carolina Resende   +2 more
doaj   +1 more source

Malignant testicular unclassified sex cord stromal tumor: a case report

Journal of Medical Case Reports, 2022
Background Most testicular tumors are germ cell tumors; sex cord stromal tumors are infrequent, accounting for only 3–5% of testicular tumors. Unclassified sex cord stromal tumors are extremely rare.
Shingo Morinaga, Shigeyuki Aoki, Toyonori Tsuzuki, Keiko Kanematsu, Naoki Kawai, Sayuri Sato, Kotomi Nakamizu, Kana Goto, Miho Niwa, Ikuko Nomura, Tomoko Sawada, Ruriko Futamachi, Fujio Morita, Yoshiaki Yamada   +13 more
doaj   +1 more source

Safety and efficacy of nivolumab plus ipilimumab in patients with advanced non-clear cell renal cell carcinoma: results from the phase 3b/4 CheckMate 920 trial

Journal for ImmunoTherapy of Cancer, 2022
Background CheckMate 920 (NCT02982954) is a multicohort, phase 3b/4 clinical trial of nivolumab plus ipilimumab treatment in predominantly US community-based patients with previously untreated advanced renal cell carcinoma (RCC) and clinical features ...
Thomas Hutson, Peter Van Veldhuizen, Michael R Harrison, Scott S Tykodi, Daniel J George, Lucio N Gordan, Robert S Alter, Edward Arrowsmith, Ivor Percent, Rakesh Singal, Joshua Zhang, Jesus Zoco, Jennifer L Johansen, Arash Rezazadeh Kalebasty   +13 more
doaj   +1 more source