Results 11 to 20 of about 35,778 (326)

Atovaquone-proguanil for treating uncomplicated Plasmodium falciparum malaria [PDF]

Cochrane Database of Systematic Reviews, 2021
The World Health Organization (WHO) in 2015 stated atovaquone-proguanil can be used in travellers, and is an option in malaria-endemic areas in combination with artesunate, as an alternative treatment where first-line artemisinin-based combination therapy (ACT) is not available or effective.
Blanshard, Andrew, Hine, Paul
openaire   +4 more sources

Azithromycin for treating uncomplicated malaria [PDF]

Cochrane Database of Systematic Reviews, 2007
To prevent the development of drug resistance, the World Health Organization (WHO) recommends treating malaria with combination therapy. Azithromycin, an antibiotic with antimalarial properties, may be a useful additional option for antimalarial therapy.To compare the use of azithromycin alone or in combination with other antimalarial drugs with the ...
Anna M, van Eijk, Dianne J, Terlouw
openaire   +2 more sources

Procalcitonin levels in children affected by severe malaria compared to those with uncomplicated malaria in the absence of bacterial infection: a cross-sectional study

Tropical Diseases, Travel Medicine and Vaccines, 2022
Background Procalcitonin is an inflammatory marker strongly associated with the presence of bacterial infection. It has been considered raised in severe malaria infection as opposed to uncomplicated malaria.
Jean-Claude Katte, Kiya Penanje, Batakeh B. Agoons, Eric Noel Djahmeni, Sharon Mbacham-Ngwafor, Vicky Jocelyne Ama Moor, Paul Koki, Wilfred Mbacham   +7 more
doaj   +1 more source

scRNA-seq reveals elevated interferon responses and TNF-α signaling via NFkB in monocytes in children with uncomplicated malaria. [PDF]

Exp Biol Med (Maywood)
Morang'a CM, Drake RS, Miao VN, Nyakoe NK, Amuzu DSY, Appiah V, Aniweh Y, Bediako Y, Bah SY, Shalek AK, Awandare GA, Otto TD, Amenga-Etego L.   +12 more
europepmc   +3 more sources

Chlorproguanil-dapsone for treating uncomplicated malaria [PDF]

Cochrane Database of Systematic Reviews, 2004
In Africa, malaria is often resistant to chloroquine and sulfadoxine-pyrimethamine. Chlorproguanil-dapsone is a potential alternative.To compare chlorproguanil-dapsone with other antimalarial drugs for treating uncomplicated falciparum malaria.We searched the Cochrane Infectious Diseases Group Specialized Register (May 2004), CENTRAL (The Cochrane ...
Bukirwa H, Garner P, Critchley J
openaire   +3 more sources

Elevation of serum interleukin-1β levels as a potential indicator for malarial infection and severe malaria: a meta-analysis

Malaria Journal, 2022
Background Interleukin (IL)-1β is a proinflammatory cytokine that has a role in disease-related inflammation, including malaria. However, reports on the effect of IL-1β on malaria severity are inconsistent. Therefore, meta-analyses to compare differences
Aongart Mahittikorn, Pattamaporn Kwankaew, Pongruj Rattaprasert, Kwuntida Uthaisar Kotepui, Frederick Ramirez Masangkay, Manas Kotepui   +5 more
doaj   +1 more source

Atovaquone-proguanil for treating uncomplicated malaria [PDF]

Cochrane Database of Systematic Reviews, 2003
Many conventional treatments for uncomplicated malaria are failing because malaria parasites develop resistance to them. One way to combat this resistance is to treat people with a combination of drugs, such as atovaquone-proguanil.To compare atovaquone-proguanil with other antimalarial drugs (alone or in combination) for treating children and adults ...
A, Osei-Akoto, L, Orton, S P O, Owusu-Ofori   +2 more
openaire   +2 more sources

Prescription patterns and compliance with World Health Organization recommendations for the management of uncomplicated and severe malaria: A prospective, real-world study in sub-Saharan Africa

Malaria Journal, 2023
Background This study aimed to evaluate the gap between guidelines and local clinical practice for diagnosis and treatment of uncomplicated and severe malaria, the patient characteristics, diagnostic approach, treatment, and compliance to standard ...
Vito Baraka, Abel Nhama, Pedro Aide, Quique Bassat, Agatha David, Samwel Gesase, Jonathan Gwasupika, Sebastian Hachizovu, Geofrey Makenga, Christian Ruchaho Ntizimira, Orikomaba Obunge, Kitoto Antoinette Tshefu, Marc Cousin, Nekoye Otsyula, Rashidkhan Pathan, Céline Risterucci, Guoqin Su, Christine Manyando   +17 more
doaj   +1 more source

Artemisinin derivatives for treating uncomplicated malaria [PDF]

Cochrane Database of Systematic Reviews, 1999
Artemisinin derivatives are a relatively new group of drugs with antimalarial properties. As resistance to other antimalarial drugs continues to increase, artemisinin drugs may be useful alternatives.The objective of this review was to assess the effects of artemisinin drugs for treating uncomplicated falciparum malaria.We searched the Cochrane ...
H M, McIntosh, P, Olliaro
openaire   +2 more sources

Increased circulating myeloid-derived suppressor cells in vivax malaria and severe falciparum malaria

Malaria Journal, 2022
Background Circulating myeloid-derived-suppressor-cells (MDSC) with immunosuppressive function are increased in human experimental Plasmodium falciparum infection, but have not been studied in clinical malaria.
Leo Leonardo, Enny Kenangalem, Jeanne R. Poespoprodjo, Rintis Noviyanti, Ric N. Price, Nicholas M. Anstey, Gabriela Minigo, Steven Kho   +7 more
doaj   +1 more source