Results 51 to 60 of about 35,778 (326)

Chlorproguanil‐dapsone (LAPDAP) for uncomplicated falciparum malaria [PDF]

Tropical Medicine & International Health, 2001
The synergistic antifolate combination of chlorproguanil with dapsone (CPG–DDS; LAPDAP) is being developed by a public–private partnership as a low‐cost treatment for uncomplicated falciparum malaria. LAPDAP is rapidly eliminated from the body, giving it low selection pressure for drug resistance.
openaire   +2 more sources

Long-term effect of uncomplicated Plasmodium berghei ANKA malaria on memory and anxiety-like behaviour in C57BL/6 mice

Parasites & Vectors, 2018
Background Cerebral malaria, the main complication of Plasmodium falciparum infection in humans, is associated with persistent neurocognitive sequels both in human disease and the murine experimental model.
Luciana Pereira de Sousa, Roberto Farina de Almeida, Flávia Lima Ribeiro-Gomes, Leonardo José de Moura Carvalho, Tadeu Mello e Souza, Diogo Onofre Gomes de Souza, Cláudio Tadeu Daniel-Ribeiro   +6 more
doaj   +1 more source

Detection of persistent Plasmodium spp. infections in Ugandan children after artemether-lumefantrine treatment [PDF]

, 2014
During a longitudinal study investigating the dynamics of malaria in Ugandan lakeshore communities, a consistently high malaria prevalence was observed in young children despite regular treatment.
AARON ATUHAIRE, COLIN J. SUTHERLAND, Dinko, Felger, Fogg, GERALD MWESIGWA, J. RUSSELL STOTHARD, JOSÉ C. SOUSA-FIGUEIREDO, JUMA NABONGE, Katz, MARTHA BETSON, MOSES ADRIKO, MOSES ARINAITWE, NARCIS B. KABATEREINE   +13 more
core   +5 more sources

Treatment of uncomplicated and severe malaria during pregnancy [PDF]

The Lancet Infectious Diseases, 2018
Over the past 10 years, the available evidence on the treatment of malaria during pregnancy has increased substantially. Owing to their relative ease of use, good sensitivity and specificity, histidine rich protein 2 based rapid diagnostic tests are appropriate for symptomatic pregnant women; however, such tests are less appropriate for systematic ...
D’Alessandro, U, Hill, J, Tarning, J, Pell, C, Webster, J, Gutman, J, Sevene, E   +6 more
openaire   +3 more sources

Plasma glutathione and oxidized glutathione level, glutathione/oxidized glutathione ratio, and albumin concentration in complicated and uncomplicated falciparum malaria

Asian Pacific Journal of Tropical Biomedicine, 2016
Objective: To compare the level of glutathione (GSH) and oxidized glutathione (GSSG), the ratio of GSH/GSSG and the concentration of albumin in plasma of patients with complicated and un-complicated falciparum malaria.
Loeki Enggar Fitri, Agustin Iskandar, Teguh Wahju Sardjono, Ummu Ditya Erliana, Widya Rahmawati, Didi Candradikusuma, Utama Budi Saputra, Eko Suhartono, Bambang Setiawan, Erma Sulistyaningsih   +9 more
doaj   +1 more source

Primacy of effective communication and its influence on adherence to artemether-lumefantrine treatment for children under five years of age: a qualitative study. [PDF]

, 2012
BACKGROUND\ud \ud Prompt access to artemesinin-combination therapy (ACT) is not adequate unless the drug is taken according to treatment guidelines. Adherence to the treatment schedule is important to preserve efficacy of the drug.
A Chinbuah, A Rowe, C Carpenter, C Falade, C Hoepfl, C Wongsrichanalai, D Ofori-Adjei, D Simba, D Simba, D Simba, D Zurovac, Daudi O Simba, Deodatus Kakoko, E Ashley, E Rutebemberwa, J Cresswell, J Nsungwa-Sabiiti, J Todd, L Conteh, M Denscombe, M DiMatteo, M DiMatteo, M George, M Gomes, M Thiede, MQ Patton, N Beer, N White, N White, P Choo, P Piola, P Piola, P Travis, R Bogdan, R Ruslami, S Kvåle, S McCombie, S Sirima, S Yeung   +38 more
core   +5 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Might procalcitonin help predict imported falciparum malaria in children?

Travel Medicine and Infectious Disease
Background: Procalcitonin (PCT) has been proposed as a marker for malaria severity in adults, with a threshold of 10 ng/ml for severe falciparum disease. Whether PCT is useful in children is debated.
Alexandra Tielli, Rachidou Ouorou, Lauren Pull, Karamo Souare, Olivier Bouchaud, Laurent Brutus, Frédérick Gay, Jean-Yves Siriez   +7 more
doaj   +1 more source

The economic burden of malaria on households and the health system in a high transmission district of Mozambique

Malaria Journal, 2019
Background Malaria remains a leading cause of morbidity and mortality in Mozambique. Increased investments in malaria control have reduced the burden, but few studies have estimated the costs of malaria in the country.
Sergi Alonso, Carlos J. Chaccour, Eldo Elobolobo, Amilcar Nacima, Baltazar Candrinho, Abuchahama Saifodine, Francisco Saute, Molly Robertson, Rose Zulliger   +8 more
doaj   +1 more source

Thiamin deficiency and uncomplicated falciparum malaria in Laos [PDF]

Tropical Medicine & International Health, 2007
SummaryObjective  Thiamin deficiency complicates severe Plasmodium falciparum malaria in Thailand and may contribute to acidosis. We therefore estimated the frequency of biochemical thiamin deficiency in patients presenting with uncomplicated falciparum malaria in southern Laos.Methods  Red cell transketolase activation coefficients (α) were measured ...
Mayxay, M, Taylor, A, Khanthavong, M, Keola, S, Pongvongsa, T, Phompida, S, Phetsouvanh, R, White, N, Newton, P   +8 more
openaire   +2 more sources