Results 61 to 70 of about 35,778 (326)

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

Varying efficacy of artesunate+amodiaquine and artesunate+sulphadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in the Democratic Republic of Congo: a report of two in-vivo studies [PDF]

, 2009
BACKGROUND: Very few data on anti-malarial efficacy are available from the Democratic Republic of Congo (DRC). DRC changed its anti-malarial treatment policy to amodiaquine (AQ) and artesunate (AS) in 2005.
A Brockman, A Nahum, A Ndayiragije, AM Kabanywanyi, AO Talisuna, AP Alker, B Greenhouse, Chantal van Overmeir, CV Plowe, Célestin Nsibu Ndosimao, D Francis, Elizabeth Ashley, G Snounou, Ingrid van den Broek, Jean-Paul Guthmann, Jean-Paul Guthmann, JG Kublin, JG Kublin, JP Guthmann, Juliet Kyomuhendo, LC Ranford-Cartwright, M Ndounga, M Ndounga, Maryline Bonnet, Michel van Herp, MR Kamya, P Piola, Pedro Pablo Palma Urrutia, R Pearce, RN Price, S Cohuet, TB Swarthout, World Health Organization   +32 more
core   +2 more sources

“More” Artificial mRNAs: Beyond the Art of Nature

Advanced Science, EarlyView.
Inspired by nature yet transcending it, synthetic mRNA is being redesigned beyond the canonical architecture. This review highlights emerging forms—circular, branched, and self‐amplifying mRNAs—that expand stability, persistence, and functional control, illustrating how artificial mRNA is evolving into a new medium for programmable biological ...
Yuanzhe Cui, Minami Fukui, Hirohisa Ohno, Hirohide Saito   +3 more
wiley   +1 more source

Genetic diversity of Plasmodium falciparum isolates from patients with uncomplicated and severe malaria based on msp-1 and msp-2 genes in Gublak, North West Ethiopia

Malaria Journal, 2019
Background Malaria infection can present with a wide variety of symptoms, ranging from mild to severe. Plasmodium falciparum isolates in uncomplicated and severe malaria infections may have different parasite genetic profiles. This study was conducted to
Hussein Mohammed, Kedir Hassen, Ashenafi Assefa, Kalkidan Mekete, Gemechu Tadesse, Girum Taye, Robert J. Commons   +6 more
doaj   +1 more source

Peroxidase‐Mimicking Nanozymes for Rapid Detection of Infectious Diseases

Advanced Science, EarlyView.
Peroxidase‐mimicking nanozymes (PMNs) have emerged as robust and versatile materials for rapid infectious disease diagnostics. This review highlights the rational design and controlled synthesis of PMNs, summarizes key biomarkers relevant to infectious diseases, examines their integration into diverse rapid detection platforms, and highlights ...
Shikuan Shao, Victor Fernandez‐Gonzalez, Xiaochuan Wang, Blake Pylipow, Claudia Herrera, Xiaohu Xia   +5 more
wiley   +1 more source

Malaria trends in districts that were targeted and not-targeted for seasonal malaria chemoprevention in children under 5 years of age in Guinea, 2014–2021

BMJ Global Health
Background Seasonal malaria chemoprevention (SMC) is a main intervention to prevent and reduce childhood malaria. Since 2015, Guinea has implemented SMC targeting children aged 3–59 months (CU5) in districts with high and seasonal malaria transmission ...
Donal Bisanzio, Richard Reithinger, Thierno Diallo, Mamadou Sitan Keita, Alioune Camara, Timothée Guilavogui, Hamidou Barry, Adam Preston, Lamine Bangoura, Eliane Mbounga, Lia S Florey, Jean-Luc Taton, Aissata Fofana   +12 more
doaj   +1 more source

Possible treatment failure of artemether-lumefantrine in an Italian traveler with uncomplicated falciparum malaria.

Mediterranean Journal of Hematology and Infectious Diseases, 2011
Artemisinin-combination therapies (ACTs) are recommended for the treatment of uncomplicated malaria in endemic areas with multidrug resistant Plasmodium falciparum.
Ernestina Carla Repetto, Claudio Giacomazzi, Antonio Traverso   +2 more
doaj   +1 more source

Addressing the challenge of neonatal mortality.

, 2013
Reducing neonatal mortality remains a challenge with an estimated 3.0 million neonatal deaths in 2011, three-quarters of these in sub-Saharan Africa and Southern Asia.
Blencowe, H, Cousens, S
core   +1 more source

Adherence to the combination of sulphadoxine-pyrimethamine and artesunate in the Maheba refugee settlement, Zambia. [PDF]

, 2004
Artemisinin-based combination therapy (ACT) is one strategy recommended to increase cure rates in malaria and to contain resistance to Plasmodium falciparum. In the Maheba refugee settlement, children aged 5 years or younger with a confirmed diagnosis of
Balkan, S, Depoortere, E, Fermon, F, Guthmann, J P, Legros, D, Nkandu, E, Sipilanyambe, N   +6 more
core   +2 more sources

Modeling the public health impact of malaria vaccines for developers and policymakers [PDF]

, 2013
Efforts to develop malaria vaccines show promise. Mathematical model-based estimates of the potential demand, public health impact, and cost and financing requirements can be used to inform investment and adoption decisions by vaccine developers and ...
Brooks, Alan, Cárdenas, Vicky, Loucq, Christian, Maire, Nicolas, Måseide, Kårstein, Nunes, Julia K., Shaffer, Craig, Smith, Thomas   +7 more
core   +1 more source