Results 81 to 90 of about 184,541 (267)
Discrete Dynamics in Nature and Society, 2021 In this study, we present an unconditionally stable positivity-preserving numerical method for the Fisher–Kolmogorov–Petrovsky–Piskunov (Fisher–KPP) equation in the one-dimensional space. The Fisher–KPP equation is a reaction-diffusion system that can be
Sangkwon Kim +8 more
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
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Journal of Inequalities and Applications, 2018 A compact finite difference (CFD) scheme is presented for the nonlinear Schrödinger equation involving a quintic term. The two discrete conservative laws are obtained.
Hanqing Hu, Hanzhang Hu
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The flutter of towed rigid decelerators [PDF]
Flutter of towed rigid decelerators, and relationships between geometric and aerodynamic parameters defining unconditional stability ...
Mac Neal, R. H.
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Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
A New Numerical Approximation Method for Two-Dimensional Wave Equation with Neumann Damped Boundary
Complexity, 2020 In this paper, a fully discretized finite difference scheme is derived for two-dimensional wave equation with damped Neumann boundary condition. By discrete energy method, the proposed difference scheme is proven to be of second-order convergence and of ...
Jiankang Liu, Suying Zhang
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Solving a System of 2D Burger\'s Equations using Semi-Lagrangian Finite Difference Schemes
پژوهشهای ریاضی, 2020 Introduction Following and generalizing the excellent work of Wang et al. [26], we extract here some new schemes, based on the semi-Lagrangian discretization, the modified equation theory, and the local one-dimensional (LOD) scheme for ...
Reza Mokhtari, Elham Feizollahi
doaj
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source