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Unconventional Immunotherapies in Cancer: Opportunities and Challenges. [PDF]
Pharmaceuticals (Basel)Alturki M +10 more
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The path to room-temperature superconductivity: A programmatic approach. [PDF]
Proc Natl Acad Sci U S APrasankumar RP +15 more
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Developmental & Comparative Immunology, 2022
Pigs are important domestic livestock and a comprehensive understanding of their immune system is critical to improve swine vaccine efficacy. Pig models represent an excellent animal model for immunological studies because of their anatomical and physiological similarities to humans.
Miaomiao Wu +4 more
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Pigs are important domestic livestock and a comprehensive understanding of their immune system is critical to improve swine vaccine efficacy. Pig models represent an excellent animal model for immunological studies because of their anatomical and physiological similarities to humans.
Miaomiao Wu +4 more
openaire +2 more sources
Unconventional T Cell Targets for Cancer Immunotherapy [PDF]
Immunity, 2018 Most studies on the immunotherapeutic potential of T cells have focused on CD8 and CD4 T cells that recognize peptide antigens (Ag) presented by polymorphic major histocompatibility complex (MHC) class I and MHC class II molecules, respectively. However, unconventional T cells, which interact with MHC class Ib and MHC-I like molecules, are also ...
Dale I Godfrey +2 more
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The burgeoning family of unconventional T cells
Nature Immunology, 2015While most studies of T lymphocytes have focused on T cells reactive to complexes of peptide and major histocompatibility complex (MHC) proteins, many other types of T cells do not fit this paradigm. These include CD1-restricted T cells, MR1-restricted mucosal associated invariant T cells (MAIT cells), MHC class Ib-reactive T cells, and γδ T cells ...
Dale I, Godfrey +4 more
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2010
1 Defining Unconventional T Cells 2 Subtypes of Unconventional T Cells: γδ T Cells 3 Subtypes of Unconventional T Cells: αβ T Cells Keywords: unconventional T cells; defining unconventional T cells; ‘professional’ antigen-presenting cells (APC); TCR gene cDNA (complementary DNA); murine dendritic epidermal T cells (DETC ...
Adrian Hayday, Carrie Steele
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1 Defining Unconventional T Cells 2 Subtypes of Unconventional T Cells: γδ T Cells 3 Subtypes of Unconventional T Cells: αβ T Cells Keywords: unconventional T cells; defining unconventional T cells; ‘professional’ antigen-presenting cells (APC); TCR gene cDNA (complementary DNA); murine dendritic epidermal T cells (DETC ...
Adrian Hayday, Carrie Steele
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Phenotypical and Functional Characterization of Cytotoxic Unconventional T-Cells
2021During the last two decades, the immunology field has been focused on the study of conventional T-cells, leading to important advances in identification of specific subsets involved in promoting and suppressing immune response in patients with cancer, autoimmune disease or transplanted patients.
Gigante M., Ranieri E.
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Unconventional recognition of peptides by T cells and the implications for autoimmunity
Nature Reviews Immunology, 2012The interaction of antigen-presenting cells with free peptides or a denatured protein can give rise to peptide-MHC class II complexes that are distinct from those generated after the processing of the whole protein. Such atypical peptide-MHC complexes can be recognized by unconventional 'type B' T cells that are not a component of the normal immune ...
James F, Mohan, Emil R, Unanue
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