Results 81 to 90 of about 29,659 (107)
Some of the next articles are maybe not open access.
Landscape of unconventional γδ T cell subsets in cancer
Molecular Biology ReportsT cells are broadly categorized into two groups, namely conventional and unconventional T cells. Conventional T cells are the most prevalent and well-studied subset of T cells. On the other hand, unconventional T cells exhibit diverse functions shared between innate and adaptive immune cells.
Parviz Azimnasab-Sorkhabi +2 more
exaly +3 more sources
Thymic development of unconventional T cells: how NKT cells, MAIT cells and γδ T cells emerge
Nature Reviews Immunology, 2020T cell lineages are defined by specialized functions and differential expression of surface antigens, cytokines and transcription factors. Conventional CD4+ and CD8+ T cells are the best studied of the T cell subsets, but 'unconventional' T cells have emerged as being more abundant and influential than has previously been appreciated.
Daniel G Pellicci +2 more
exaly +3 more sources
The unconventional role of LTαβ in T cell differentiation
Trends in Immunology, 2007Lymphotoxin (LT)αβ, a member of the tumor necrosis factor cytokine superfamily, and its receptor, the LTβ receptor (LTβR), have a well defined role in secondary lymphoid organogenesis but an unexpected function in T cell differentiation. Although earlier studies indicated that conventional T cell subsets were normal in mice deficient in the LTβR ...
Dirk Elewaut, Carl F. Ware
openaire +1 more source
Breaking the mold: Unconventional T cells in cancer therapy
Cancer CellUnconventional T cells, including invariant natural killer T (iNKT) cells, gamma delta (γδ) T cells, and mucosal-associated invariant T (MAIT) cells, play important roles in both innate and adaptive immunity. These cells respond to tumors rapidly and influence the tumor microenvironment (TME).
Yan-Ruide, Li +4 more
openaire +2 more sources
Unconventional T cells in colon adenocarcinomas
2023Many factors influence the initiation and growth of tumours. The infiltration and activity of immune cells in the tumour microenvironment are widely recognised as key factors affecting the clinical outcome of cancer. In this context, conventional T cells have been studied thoroughly but much less is known about the enigmatic populations of ...
openaire +1 more source
Activation and Function of Unconventional T Cells
2018Efferent innate immune responses include the function of unconventional T cells with partial innate properties. While most studies of T lymphocytes have focused on T cells involved in adaptive immune responses by reacting to complexes of peptide and major histocompatibility complex proteins, many other types of T cells do not match this paradigm.
openaire +1 more source
Introduction to the special issue on “unconventional T cells”
Seminars in Immunology, 2022Legoux, François, Lantz, Olivier
openaire +3 more sources
2005
This review builds on evidence that cell-mediated immune responses to bacteria, viruses, parasites, and tumors are an integration of conventional and unconventional T-cell activities. Whereas conventional T cells provide clonal antigen-specific responses, unconventional T cells profoundly regulate conventional T cells, often suppressing their ...
Pennington, Daniel +5 more
openaire +4 more sources
This review builds on evidence that cell-mediated immune responses to bacteria, viruses, parasites, and tumors are an integration of conventional and unconventional T-cell activities. Whereas conventional T cells provide clonal antigen-specific responses, unconventional T cells profoundly regulate conventional T cells, often suppressing their ...
Pennington, Daniel +5 more
openaire +4 more sources
IGSF4 expression by unconventional T cells: A role in T-T interaction? [PDF]
, 2007 info:eu-repo/semantics ...
Roberts, A +5 more
openaire
Unconventional T cells in chronic disease and as targets of therapy
Clinical and Experimental Immunology, 2023Samuel B, Shin, Kelly M, McNagny
openaire +2 more sources