Results 261 to 270 of about 127,036 (330)
Molecular bases of mitochondrial uncoupling protein 1 induced thermogenesis
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2018 Mathilde S. Piel +6 more
openaire +1 more source
Effects of Tributyltin Chloride on Human Neuronal Differentiation and Mice Brain Development
Environmental Toxicology, EarlyView.ABSTRACT According to the developmental origins of health and disease hypothesis, perinatal exposure to an environmental toxicant during the development of the nervous system could cause a permanent cellular modification that may promote the appearance of neurodegenerative diseases at an older age.
Ester López‐Gallardo +10 more
wiley +1 more source
VIEW, EarlyView.The limitations of conventional techniques hinder the identification of natural compounds with anticancer potential in terms of speed, throughput, sensitivity, and capability of continuous monitoring of relevant biological effects. Novel label‐free optical biosensors represent new opportunities in the discovery of drug candidates, eliminating these ...
Beatrix Péter +10 more
wiley +1 more source
VIEW, EarlyView.This study investigates the molecular alterations underlying angiotensin II (Ang II)‐induced vascular remodeling in cardiovascular diseases using a multi‐omics approach. Through data exploration and integrated multi‐omics analysis, our findings reveal that Ang II‐driven vascular injury in vascular smooth muscle cells is mediated by metabolic ...
Yiwei Hu +8 more
wiley +1 more source
Fibroblast growth factor 8b induces uncoupling protein 1 expression in epididymal white preadipocytes. [PDF]
Sci Rep, 2019 Westphal S +5 more
europepmc +1 more source
Blubber Thickening Driven by UCP1 Inactivation: Insights from a Cetacean‐Like Transgenic Mouse Model
Integrative Zoology, EarlyView.UCP1 inactivation of cetaceans in mice drives BAT whitening and iWAT hyperplasia, promoting fat accumulation for aquatic adaptation. Abstract Cetaceans possess thick blubber, a specialized adipose tissue essential for thermal insulation, a streamlined body form, energy storage, and buoyancy. However, the mechanisms that underpin this adaptation are not
Qian Zhang +5 more
wiley +1 more source
Allergy, EarlyView.This study examines the association between the rs1042713 (Arg16Gly) polymorphism of the β2‐adrenergic receptor and the risk of severe eosinophilic asthma, as well as its influence on mepolizumab long‐term effectiveness and clinical remission. The Arg16 allele is associated with increased risk of severe disease and potentially diminished long‐term ...
Santi Nolasco +38 more
wiley +1 more source