Results 21 to 30 of about 491 (150)

Efficacy and Safety of Undenatured Type II Collagen in The Treatment of Osteoarthritis of The Knee: A Randomized, Double-blind, Placebo-controlled Trial

Indonesian Biomedical Journal, 2023
BACKGROUND: Available medication for pain and joint stiffness release in osteoarthritis (OA) often gives considerable side effects. Undenatured type II collagen (UC-II) has been considered as a treatment for OA for its ability to prevent the progress of ...
Oentarini Tjandra, Shirly Gunawan, Johan Johan, Fia Fia Lie, Marcella Erwina Rumawas, Agus Limarta   +5 more
doaj   +4 more sources

Undenatured collagen type II for the treatment of osteoarthritis: a review

International Journal of Research in Orthopaedics, 2018
<p class="abstract">Osteoarthritis is a prevalent musculoskeletal condition worldwide with rising rates in elderly people. Both mechanical and immunological factors are implicated in the pathogenesis of osteoarthritis resulting in destruction of the articular cartilage.
Ram Prabhoo, Gauri Billa
openaire   +3 more sources

Correction: Fan et al. Native Collagen II Relieves Bone Impairment through Improving Inflammation and Oxidative Stress in Ageing db/db Mice. Molecules 2021, 26, 4942

Molecules, 2022
The authors would like to correct spelling mistakes (undenatured type II collagen) in the title, as well as in the main manuscript including the tables and figures in the title paper [...]
Rui Fan, Yuntao Hao, Xinran Liu, Jiawei Kang, Jiani Hu, Ruixue Mao, Rui Liu, Na Zhu, Meihong Xu, Yong Li   +9 more
doaj   +2 more sources

Efficacy and safety of native type II collagen in modulating knee osteoarthritis symptoms: a randomised, double‐blind, placebo‐controlled trial

Journal of Experimental Orthopaedics, 2022
Purpose Knee osteoarthritis (OA) is the most common form of clinical arthritis in middle‐aged and older individuals. Undenatured or native type II (TII) collagen derived from the chicken sternum has a good therapeutic effect on relieving severe pain of ...
Cheng Luo, Weike Su, Ying Song, Shalini Srivastava   +3 more
doaj   +2 more sources

Efficacy and tolerability of native (undenatured) type II collagen supplementation for joint health in healthy volunteers: a randomized double-blind placebo-controlled study [PDF]

Nutrition Journal
Background In non-osteoarthritic individuals, the appearance of joint discomfort with physical activity is a potential indicator of initial joint degeneration. The present study aimed to evaluate the efficacy and tolerability of native (undenatured) type-
Ingrid Möller, Kirsten Martínez, Andrea Terradillos-Guillén, Ester Costa-Larrión, Daniel Martínez-Puig, Javier Velasco-Álvarez   +5 more
doaj   +2 more sources

Pain reduction and tolerance of type II undenatured collagen in patients with knee osteoarthritis

International Journal of Research in Orthopaedics, 2023
Background: Osteoarthritis (OA) is the most common cause of pain and disability in adults. Dietary supplements such as undenatured type II collagen (UC-II) have shown to have some benefits in OA treatment. This study aimed to assess changes in pain levels among knee OA patients treated with UC-II for 6 months.
Tomás F. Fernández-Jaén, Carlos González de Vega, Paula Saiz, Per Björk, Elena Rodríguez-Iñigo, Juan Manuel Lopez-Alcorocho, Franchek Drobnic, Pedro Guillén-García   +7 more
openaire   +3 more sources

Biologically active additives in the 21st century: undenatured type II collagen as an example of good medical practice

Современная ревматология, 2020
The paper deals with an update on biologically active additives (BAAs) and emphasizes their role in normalizing and/or improving the functional status of organs and systems, including the gastrointestinal tract microflora, in reducing the risk of ...
I. S. Dydykina, D. A. Dibrov, K. S. Nurbaeva, P. S. Kovalenko, A. A. Kovalenko   +4 more
doaj   +3 more sources

Novel formulations ameliorate osteoarthritis in rats by inhibiting inflammation and oxidative stress. [PDF]

Food Sci Nutr
Treatments F1 (curcuminoids + gingerols + AKBA) to F4 (curcuminoids + AKBA) improved joint diameter, stride length, and paw area in OA rats. They significantly reduced MDA levels and increased antioxidant enzyme activities by lowering inflammatory markers such as IL‐1β, IL‐6, MMP‐8, TNF‐α, CRP, COMP, and LOX‐5, while increase the anti‐inflammatory ...
Erten F, Ozdemir O, Tokmak M, Durmus AS, Ozercan IH, Morde A, Padigaru M, Sahin K.   +7 more
europepmc   +2 more sources

Modeling treatment of osteoarthritis with standard therapy and senolytic drugs. [PDF]

PLoS ONE
Osteoarthritis (OA), the most common form of joint disease, involves the progressive degradation of articular cartilage and is a major cause of chronic disability in aging populations.
Nourridine Siewe, Avner Friedman
doaj   +2 more sources

Efficacy of oral nutrition supplementation enriched with hydroxymethylbutyrate (HMB) and undenatured type-II collagen (UC-II) combined with exercise training on osteoarthritis-related outcomes among adults with knee osteoarthritis in Klang Valley of Malaysia: study protocol for a randomised controlled trial [PDF]

BMJ Open
Introduction Knee osteoarthritis (OA) is a serious public health problem since it is linked to loss of muscular function and independence, especially in older adults. In this study, the researchers have proposed a randomised controlled trial with a three-
Suzana Shahar, Yee Xing You, Sumaiyah Mat, Munirah Ismail, Anastasia Xin Wei Yap, Devinder Kaur Ajit Singh, Ching Phang Chong, Nor Hamdan Mohamad Yahaya, Juliana Fairuz Maktar, Rizal Abdul Rani, Theng Choon Ooi, Wan Chien Han, Lee Kuan Kwan, Centhyea Centhyea   +13 more
doaj   +2 more sources