Results 71 to 80 of about 28,738 (154)

Biologically active additives in the 21st century: undenatured type II collagen as an example of good medical practice

Современная ревматология, 2020
The paper deals with an update on biologically active additives (BAAs) and emphasizes their role in normalizing and/or improving the functional status of organs and systems, including the gastrointestinal tract microflora, in reducing the risk of ...
I. S. Dydykina, D. A. Dibrov, K. S. Nurbaeva, P. S. Kovalenko, A. A. Kovalenko   +4 more
doaj   +1 more source

Diallyl Trisulfide From Garlic Regulates RAB18 Phase Separation to Inhibit Lipophagy and Induce Cuproptosis in Hepatic Stellate Cells for Antifibrotic Effects

Advanced Science, Volume 12, Issue 21, June 5, 2025.
Diallyl trisulfides (DATs) selectively induce cuproptosis in hepatic stellate cells (HSCs) by targeting Ras‐related protein Rab‐18 (RAB18) and regulating lipophagy. DATs promote RAB18 phase separation, enhance mitochondrial‐associated membrane structures (MAMs) formation, and increase succinylation of dihydrolipoamide dehydrogenase (DLD) at K320.
Haoyuan Tian, Shujiang Sun, Xinran Qiu, Junrui Wang, Yuanyuan Gao, Jianmei Chen, Xiang Han, Zhengyang Bao, Xiaohan Guo, Yuqi Sun, Yuxin Lin, Mengru Hu, Feng Zhang, Zili Zhang, Feixia Wang, Shizhong Zheng, Jiangjuan Shao   +16 more
wiley   +1 more source

Preparation of Collagen Peptide Nanoliposomes From Sturgeon Fish Cartilage and Explore Their Anti‐Osteoarthritis Effects in Rats

Food Frontiers, Volume 6, Issue 2, Page 727-749, March 2025.
This study aims to extract pepsin soluble collagen from sturgeon cartilage, hydrolyze to collagen peptides and prepare SCCP nanoliposomes to explore the treatment effects of osteoarthritis in rats. ABSTRACT This study aims to extract pepsin soluble collagen (PSC) from sturgeon cartilage, hydrolyze to sturgeon cartilage collagen peptides (SCCP), and ...
Chia‐Chi Kung, Mei‐Zhen Lin, Bing‐Huei Chen   +2 more
wiley   +1 more source

Pengaruh Bauran Pemasaran Terhadap Keputusan Peresepan Undenatured Type II Collagen Dalam Penatalaksanaan Osteoartritis Lutut

Farmasains, 2019
Osteoartritis merupakan penyakit sendi yang paling sering dialami oleh manusia, terutama lutut. Osteoartritis lutut terjadi sekitar 15,5% pada pria dan 12,7% pada wanita di Indonesia.
Muhammad Yamin, D Henky Lesmana
doaj   +1 more source

A Literature Review of Undenatured type II collagen (UC-II) in Joint Health and Disease

International Journal of Current Science Research and Review, 2022
Undenatured type II collagen (UC-II) is supplementary which is from chicken sternum cartilage. (Lugo, J. P., Saiyed,…,2015) UC-II has undenatured type II collagen componentand. The safety and capability of UC-II in adjusting joint discomfort in Osteoarthritis and Rheumatoid arthritis support by previous preclinical and clinical studies. (Lugo, J.
openaire   +2 more sources

Influence of Cross‐Linking by Microbial Transglutaminase on Physicochemical Properties of Eggshell Membrane Collagen

Journal of Food Processing and Preservation, Volume 2025, Issue 1, 2025.
Collagen from eggshell membrane (EM) was stabilized via a cross‐linking procedure using microbial transglutaminase as an alternative, nontoxic cross‐linking reagent for its low stability and low mechanical strength. The physicochemical features of collagen solutions (5 mg/mL), which were cross‐linked by different concentrations of MTG (30, 40, 50, 60 ...
Elahe Kazemi Kheirabadi, Poorandokht Kheirandish, Seyed Hadi Razavi, Mohammad-Taghi Golmakani, Essam Hebishy   +4 more
wiley   +1 more source

Evidence base of pharmaconutraceuticals with chondroprotective action

Лечащий Врач
Background. Osteoarthritis is one of the most common chronic diseases of the musculoskeletal system worldwide, being a common cause of chronic pain syndrome and disability.
O. A. Shavlovskaya, I. D. Romanov, I. A. Bokova   +2 more
doaj   +1 more source

Significant Discrepancies in “Functional Characterization of Undenatured Type II Collagen Supplements: Are They Interchangeable?”: A Rejoinder

Journal of Dietary Supplements, 2022
In 2021, an article was published comparing two commercial products containing undenatured type II collagen: b-2Cool® (Bioiberica, S.A.U., Barcelona, Spain; designated CII-X, X1, and X2) and UC-II (Lonza Consumer Health Inc, USA; designated CII-Y, Y1, and Y2). However, we feel certain concerns remain where clarification may be warranted.
openaire   +2 more sources

Current evidence for non‐pharmaceutical, non‐surgical treatments of canine osteoarthritis

Journal of Small Animal Practice, Volume 65, Issue 1, Page 3-23, January 2024.
Osteoarthritis is a progressive degenerative disease process that affects a significant proportion of the canine population, impacting these animals' quality of life. Currently, there is no cure and treatment consists of managing the clinical signs of pain and reduced mobility.
C. Pye, N. Clark, N. Bruniges, M. Peffers, E. Comerford   +4 more
wiley   +1 more source

1H-NMR metabolomic profile of healthy and osteoarthritic canine synovial fluid before and after UC-II supplementation

Scientific Reports, 2022
The aim of the study was to compare the metabolomic synovial fluid (SF) profile of dogs affected by spontaneous osteoarthritis (OA) and supplemented with undenatured type II collagen (UC-II), with that of healthy control dogs.
Marzia Stabile, Chiara Roberta Girelli, Luca Lacitignola, Rossella Samarelli, Antonio Crovace, Francesco Paolo Fanizzi, Francesco Staffieri   +6 more
doaj   +1 more source