Results 71 to 80 of about 406 (135)

1H-NMR metabolomic profile of healthy and osteoarthritic canine synovial fluid before and after UC-II supplementation

Scientific Reports, 2022
The aim of the study was to compare the metabolomic synovial fluid (SF) profile of dogs affected by spontaneous osteoarthritis (OA) and supplemented with undenatured type II collagen (UC-II), with that of healthy control dogs.
Marzia Stabile, Chiara Roberta Girelli, Luca Lacitignola, Rossella Samarelli, Antonio Crovace, Francesco Paolo Fanizzi, Francesco Staffieri   +6 more
doaj   +1 more source

Comparative Analysis of Collagen Supplementation Forms and Their Effects on Multiple Health Parameters

Journal of Education, Health and Sport
Collagen, a key structural protein, is essential for maintaining the integrity of connective tissues such as skin, cartilage, tendons, bones. As natural collagen production decreases with age and is further compromised by environmental factors such as ...
Robert Siemiątkowski, Mateusz Haber, Adrianna Czachor, Paula Kula, Adam Juśkiewicz, Olga Grelewicz, Natalia Kucy, Elwira Servaas, Alicja Kotula   +8 more
doaj   +1 more source

Undenatured Type II Collagen

Abstract Undenatured type II collagen (UC-II) represents a unique category of joint health intervention, mechanistically distinct from hydrolyzed collagen or amino acid supplementation. By retaining its native triple-helical epitopes, UC-II engages the mechanism of oral tolerance, wherein antigens presented through gut-associated lymphoid tissue ...
openaire   +1 more source

Experience with the use of undenatured type II collagen in patients with stage III knee osteoarthritis: a multicenter, prospective, double-blind, placebo-controlled, randomized trial

Терапевтический архив
Introduction. Current strategies for treating osteoarthritis (OA) are based on a multimodal approach that includes pharmacological and non-pharmacological methods.
Liudmila I. Alekseeva, Natalia G. Kashevarova, Elena A. Taskina, Ekaterina A. Strebkova, Tatiana A. Korotkova, Evgenia P. Sharapova, Natalya M. Savushkina, Aleksander M. Lila, Nadezhda A. Shostak, Irina I. Nesterovich, Viktoriia A. Dedkova, Vasiliy B. Vasilyuk, Natalia V. Egorova, Marina A. Leontyeva, Svetlana P. Yakupova, Irina B. Vinogradova, Valentina N. Sorotskaya, Larisa I. Shirokova, Alla V. Rudakova   +18 more
doaj   +1 more source

On the immunotropic effects of a new combined pharmaconutraceutical preparation in osteoarthritis

Современная ревматология
Osteoarthritis (OA) is one of the leading causes of disability in the world, but the efficacy and safety of its treatment remain extremely low.
I. V. Sarvilina, A. M. Lila, O. A. Gromova   +2 more
doaj   +1 more source

Impact of supplemented undenatured type II collagen on pain and mobility in healthy Labrador Retrievers during an exercise regimen. [PDF]

Transl Anim Sci, 2022
Varney JL, Fowler JW, Coon CN.
europepmc   +1 more source

Undenatured type II collagen mitigates inflammation and cartilage degeneration in healthy Labrador Retrievers during an exercise regimen. [PDF]

Transl Anim Sci, 2021
Varney JL, Fowler JW, Coon CN.
europepmc   +1 more source

Efficacy, safety and prospects of using a combination of native type II collagen, methylsulfonylmethane, boswellic acids, vitamin C and vitamin D₃ in knee osteoarthritis: a resolution of the Expert panel

Терапевтический архив
A meeting of the Expert Council on September 9, 2023 considered the last challenges in the treatment of osteoarthritis (OA) including OA in comorbid patients.
Vadim I. Mazurov, Liudmila I. Alekseeva, Irina B. Belyaeva, Igor G. Belenkiy, Artem L. Burulev, Inna Z. Gaydukova, Elena V. Zonova, Oleg V. Kalyuzhin, Olga B. Nesmeyanova, Elvira N. Otteva, Evgeniy A. Trofimov   +10 more
doaj   +1 more source

DMOADs and DMARDs in the treatment of patients with joint and spine diseases

Фармакоэкономика
The data on the classification of drugs, which are prescribed for the treatment of patients with joint and spine diseases, such as osteoarthritis (OA) and rheumatoid arthritis (RA), are presented.
O. A. Shavlovskaya
doaj   +1 more source

Generalized osteoarthritis: ways to search effective pharmacotherapy

Лечащий Врач
Background. Osteoarthritis is a heterogeneous disease characterized by lesions of one or more joints, diversity of clinical features, and a large palette of biochemical and molecular characteristics, which together suggests the existence of multiple ...
I. N. Sarvilina, A. G. Nazarenko, T. B. Minasov, O. A. Gromova   +3 more
doaj   +1 more source