Results 61 to 70 of about 491 (150)
International Journal of Research in Orthopaedics, 2021 <p class="abstract">Osteoarthritis (OA) is the most common joint disease affecting millions worldwide. Osteoarthritis typically affects the knees, hands, hips, and feet. It is characterized by complex pathologic changes in cartilage which haven’t been fully elucidated yet.
Karun Jain +4 more
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Pharmacotherapy of pain in musculoskeletal diseases: evolution and revolution of views
Неврология, нейропсихиатрия, психосоматика, 2022 The article presents new views on the treatment of pain syndromes in musculoskeletal diseases, in particular in osteoarthritis (OA) of various localizations (gonarthrosis, coxarthrosis).
O. A. Shavlovskaya +6 more
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Piroxicam‐Collagen‐Based Sponges for Medical Applications
International Journal of Polymer Science, Volume 2019, Issue 1, 2019., 2019 Depending on the concentration of the drug and/or the method of administration, drugs could be used in various ways. To take full advantage of the drug beneficial properties in oral medical interventions but also in other types of surgery, like plastic surgery, general surgery, or gynecological surgery, the drug concentration as well as the ...
Daniel-Cristian Ioan +7 more
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Disease-modifying osteoarthritis drugs (DMOADs): new trends in osteoarthritis therapy
Фармакоэкономика, 2023 The review examines pharmacological agents that can have potential disease-modifying osteoarthritis drugs (DMOADs) status. DMOADs prevent the progression and further structural joint damage (structure-modifying effect), leading to a decrease in symptoms ...
O. A. Shavlovskaya +5 more
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The FASEB Journal, Volume 32, Issue 12, Page 6771-6782, December 2018., 2018 ABSTRACT Matrix protease activity is fundamental to developmental tissue patterning and remains influential in adult homeostasis. In cartilage, the principal matrix proteoglycan is aggrecan, the protease‐mediated catabolism of which defines arthritis; however, the pathophysiologic mechanisms that drive aberrant aggrecanolytic activity remain unclear ...
Clarissa R. Coveney +5 more
wiley +1 more source
A Literature Review of Undenatured type II collagen (UC-II) in Joint Health and Disease
International Journal of Current Science Research and Review, 2022 Undenatured type II collagen (UC-II) is supplementary which is from chicken sternum cartilage. (Lugo, J. P., Saiyed,…,2015) UC-II has undenatured type II collagen componentand. The safety and capability of UC-II in adjusting joint discomfort in Osteoarthritis and Rheumatoid arthritis support by previous preclinical and clinical studies. (Lugo, J.
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Critical Public HealthCollagen has emerged as a potential pharmacotherapeutic intervention for knee osteoarthritis (OA). This study evaluates the effectiveness and safety of undenatured collagen type II among patients with knee OA and healthy subjects without joint-related ...
Cuiqing Chang, Yimin Zhao, Wei Liu
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Journal of Dietary Supplements, 2022 In 2021, an article was published comparing two commercial products containing undenatured type II collagen: b-2Cool® (Bioiberica, S.A.U., Barcelona, Spain; designated CII-X, X1, and X2) and UC-II (Lonza Consumer Health Inc, USA; designated CII-Y, Y1, and Y2). However, we feel certain concerns remain where clarification may be warranted.
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Comprehensive Reviews in Food Science and Food Safety, Volume 24, Issue 4, July 2025.ABSTRACT Packaging reduction, particularly in terms of single‐use plastic (SUP) packaging waste, as well as restrictions on specific packaging formats and regulatory requirements, are driving the demand for sustainable packaging solutions. Notably, within the category of SUP products, packaging accounts for the highest share at 40%. Therefore, advanced
Lokesh Kumar +3 more
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Advanced Science, Volume 12, Issue 21, June 5, 2025.Diallyl trisulfides (DATs) selectively induce cuproptosis in hepatic stellate cells (HSCs) by targeting Ras‐related protein Rab‐18 (RAB18) and regulating lipophagy. DATs promote RAB18 phase separation, enhance mitochondrial‐associated membrane structures (MAMs) formation, and increase succinylation of dihydrolipoamide dehydrogenase (DLD) at K320.
Haoyuan Tian +16 more
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